Patent US5855578A successfully refreshed from Google Patents.
US5855578A
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US
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Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
Assignee: University of California
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Filing: 1997-02-14
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Granted: 1999-01-05
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Expires: 2017-02-14
Abstract
Abstract An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.
Inventors
- 👤 Guido Guglielmi
- 👤 Ivan Sepetka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:47
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/09; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12113; A61B17/12131; A61B17/1214; A61B17/12145; A61B17/1215; A61B17/12168; A61B17/12172; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B17/00234; A61B2017/00292; A61B2017/1205; A61B2017/12054; A61B2017/12063; A61B2017/12095; A61B17/22; A61B2017/22038; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00761; A61B2018/00773; A61B2018/00875; A61B2018/00886; A61B18/1206; A61B2018/1226; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1435; A61B2018/1495; A61B90/00; A61B90/39; A61B2090/3966; A61M2025/09175
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
68 words
An apparatus for forming an occlusion within a body cavity having an ionic fluid therein comprising: a wire adapted to be disposed near an opening into said body cavity; a separable distal tip of said wire adapted for disposition into said body cavity to form said occlusion within said body cavity about said distal tip; and an electrolytically detachable connecting segment coupling said distal tip and said wire.
Claim 2
Independent Claim
68 words
An apparatus for forming an occlusion within a body cavity having an ionic fluid therein comprising: a wire adapted to be disposed near an opening into said body cavity; a separable distal tip of said wire adapted for disposition into said body cavity to form said occlusion within said body cavity about said distal tip; and an electrolytically detachable connecting segment coupling said distal tip and said wire.
Claim 3
Dependent Claim
40 words
The apparatus of claim 1 where said distal tip has a length and flexibility to allow said distal tip sufficiently to impede flow of said fluid in said body cavity when said distal tip is disposed in said body cavity.
Claim 4
Dependent Claim
36 words
The apparatus of claim 2 where said distal tip is comprised of a radio-opaque material and has a long and pliable length sufficient to cause said cavity to appear substantially opaque as determined by fluoroscopic examination.
Claim 5
Dependent Claim
30 words
The apparatus of claim 2 where said distal tip is comprised of a plurality of segments which collectively cause said cavity to appear substantially opaque as determined by fluoroscopic examination.
Claim 6
Dependent Claim
36 words
The apparatus of claim 1 where said connecting segment electrolytically detaches said distal tip from said wire by electrolytically disintegrating at least one portion of said connecting segment extending between said wire and said distal tip.
Claim 7
Dependent Claim
20 words
The apparatus of claim 4 where said connecting segment is a coil segment which is electrolytically disintegrated to effect detachment.
Claim 8
Dependent Claim
70 words
The apparatus of claim 1 further comprising a catheter into which said wire, distal tip and connecting segment are disposed, and where said connecting segment is retained with said catheter and not at first exposed to said fluid to allow formation of said occlusion about said distal tip, and is then subsequently extended out of said catheter and exposed to said fluid to separate said distal tip from said wire.
Claim 9
Independent Claim
137 words
An apparatus for use in formation of an occlusion used in combination with a catheter comprising: an electrolyzable core wire having a distal portion; and a separable elongate tip portion extending said core wire and coupled to said distal portion of said core wire, said separable elongate tip portion for insertion within a body cavity, said separable elongate tip portion not resistant to electrolytic disintegration in fluid as compared to said electrolyzable core wire, and said separable elongate tip portion being detachable from said core wire by electrolysis, wherein said separable elongate tip portion is a long and substantially flexible segment and is comprised of a metal not as susceptible to electrolytic disintegration within fluid as said core wire, and wherein said long and flexible segment is prebiased to form a helix when extended from said catheter.
Claim 10
Independent Claim
137 words
An apparatus for use in formation of an occlusion used in combination with a catheter comprising: an electrolyzable core wire having a distal portion; and a separable elongate tip portion extending said core wire and coupled to said distal portion of said core wire, said separable elongate tip portion for insertion within a body cavity, said separable elongate tip portion not resistant to electrolytic disintegration in fluid as compared to said electrolyzable core wire, and said separable elongate tip portion being detachable from said core wire by electrolysis, wherein said separable elongate tip portion is a long and substantially flexible segment and is comprised of a metal not as susceptible to electrolytic disintegration within fluid as said core wire, and wherein said long and flexible segment is prebiased to form a helix when extended from said catheter.
Claim 11
Dependent Claim
12 words
The apparatus of claim 8 wherein said helix has a conical envelope.
Claim 12
Dependent Claim
12 words
The apparatus of claim 8 wherein said helix has a cylindrical envelope.
Claim 13
Independent Claim
70 words
A method for forming an occlusion within a body cavity having an ionic fluid therein comprising the steps of: disposing a separable distal tip of a wire into said body cavity to form said occlusion within said body cavity about said distal tip; and electrolytically detaching said distal tip from said wire to leave said distal tip within said body cavity with said occlusion being formed within said body cavity.
Claim 14
Independent Claim
70 words
A method for forming an occlusion within a body cavity having an ionic fluid therein comprising the steps of: disposing a separable distal tip of a wire into said body cavity to form said occlusion within said body cavity about said distal tip; and electrolytically detaching said distal tip from said wire to leave said distal tip within said body cavity with said occlusion being formed within said body cavity.
Claim 15
Dependent Claim
42 words
The method of claim 11 where said step of disposing said distal tip of said wire disposes said distal tip into said body cavity to occupy said cavity to a degree sufficient to impede flow of a fluid in said body cavity.
Claim 16
Dependent Claim
26 words
The method of claim 12 where said step of disposing said distal tip of said wire disposes a distal tip having a long and pliable length.
Claim 17
Dependent Claim
32 words
The method of claim 11 where said step of electrolytically detaching said distal tip of said wire electrolytically disintegrates a connecting coupling between said wire and said distal tip to effect separation.
Claim 18
Dependent Claim
56 words
The method of claim 14 further comprising the step of shielding said coupling between said wire and distal tip from said fluid by disposing said coupling in a catheter to allow formation of said occlusion about said distal tip, and then exposing said coupling to said fluid to electrolytically separate said distal tip from said wire.
Claim 19
Dependent Claim
52 words
The method of claim 11 further comprising the step of repeating said steps of disposing a separable distal tip of a wire, and electrolytically detaching said distal tip, wherein a plurality of said distal tips are separated and disposed in said body cavity to collectively form an occlusion in said body cavity.
Claim 20
Independent Claim
93 words
A method of using a catheter to form an occlusion comprising: disposing an electrolyzable core wire near the situs of said occlusion; disposing a separable elongate tip portion extending from said catheter and coupled to said core wire at said situs of said occlusion, said separable elongate tip portion being more resistant to electrolytic disintegration in fluid than said electrolyzable core wire, and being a long and substantially flexible segment prebiased to form a helix when extended from said catheter; and detaching said separable elongate tip portion from said core wire by electrolysis.
Claim 21
Independent Claim
93 words
A method of using a catheter to form an occlusion comprising: disposing an electrolyzable core wire near the situs of said occlusion; disposing a separable elongate tip portion extending from said catheter and coupled to said core wire at said situs of said occlusion, said separable elongate tip portion being more resistant to electrolytic disintegration in fluid than said electrolyzable core wire, and being a long and substantially flexible segment prebiased to form a helix when extended from said catheter; and detaching said separable elongate tip portion from said core wire by electrolysis.
Claim 22
Dependent Claim
22 words
The method of claim 17 where said step of disposing said separable elongate tip portion disposes said helix with a cylindrical envelope.
Claim 23
Dependent Claim
22 words
The method of claim 17 where said step of disposing said separable elongate tip portion disposes said helix with a conical envelope.
Claim 24
Independent Claim
99 words
An apparatus for use in formation of an occlusion within a body cavity comprising: a core wire having at least a electrolyzable distal portion; and a separable elongate tip portion of said core wire coupled to and extending from said core wire, said separable elongate tip portion adapted to form said occlusion in said body cavity and being adapted for insertion within said body cavity, said separable elongate tip portion being resistant to electrolysis compared to said distal portion of said core wire, said separable elongate tip portion being coupled to said core wire by said electrolyzable distal portion.
Claim 25
Independent Claim
99 words
An apparatus for use in formation of an occlusion within a body cavity comprising: a core wire having at least a electrolyzable distal portion; and a separable elongate tip portion of said core wire coupled to and extending from said core wire, said separable elongate tip portion adapted to form said occlusion in said body cavity and being adapted for insertion within said body cavity, said separable elongate tip portion being resistant to electrolysis compared to said distal portion of said core wire, said separable elongate tip portion being coupled to said core wire by said electrolyzable distal portion.
Claim 26
Dependent Claim
48 words
The apparatus of claim 20 further comprising a stainless steel segment, said stainless steel segment comprising a coil having a proximate and distal end and connected at its proximate end to said core wire and connected at its distal end to said elongate tip portion of said apparatus.
Claim 27
Dependent Claim
19 words
The apparatus of claim 21 wherein said coil defines an interior space, said interior space being free and unreinforced.
Claim 28
Dependent Claim
34 words
The apparatus of claim 20 wherein said separable elongate tip portion is a long and substantially flexible segment and is comprised of a metal not as susceptible to electrolytic disintegration as said core wire.
Claim 29
Dependent Claim
41 words
The apparatus of claim 23 wherein said long and flexible segment of said elongate tip portion has a length such that when disposed in said body cavity it assumes a form which substantially impedes flow of fluid in said body cavity.
References Cited (Backward Citations)
US4346712A
Cited
US4522205A
Cited
DE3203410A1
Cited
US4512338A
Cited
WO1984004686A1
Cited
US4748986A
Cited
US4735201A
Cited
US4739768B1
Cited
US4739768A
Cited
US4739768B2
Cited
US4820298A
Cited
US4884579A
Cited
US4994069A
Cited
WO1991013592A1
Cited
US5122136A
Cited
US5108407A
Cited
WO1992001425A1
Cited
WO1993011825A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-01-04 | 2002-07-06 | 2003-01-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-01-04 | 2006-07-06 | 2007-01-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-01-04 | 2010-07-06 | 2011-01-05 | $7700.00 | Window Closed / Lapsed |