US5782797A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Therapeutic infusion device
Assignee: Boston Scientific Scimed Inc
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Filing: 1996-06-06
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Granted: 1998-07-21
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Expires: 2016-06-06
Abstract
Abstract A method of treating an acute occlusion of the human vasculature as in stroke. The method includes providing a device flexible enough to be steered within the tortuous anatomy and still have the ability to be pushed across a thrombic occlusion. The device further provides two distinct sets of infusion lumens. The method includes advancing the device through the vasculature such that one infusion lumen is located distal to the thrombic occlusion and the other infusion lumen is located proximal to the occlusion. A neuroprotective drug is then infused through an opening distal to the occlusion and a thrombolytic agent infused through an opening proximal to the occlusion thereby dissolving the occlusion while minimizing damage to tissues distal to the occlusion.
Inventors
- 👤 Cyril J. Schweich, Jr.
- 👤 Julie A. Brunner
- 👤 Todd J. Mortier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 00:10
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/0021; A61M25/0023; A61M25/0026; A61M2025/0039; A61M25/0067; A61M25/0074; A61M2025/0079; A61M25/0068; A61M25/007
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
174 words
A method of treating thrombus that is lodged in a human vasculature, comprising the steps of: i. providing a device having: (a) an elongate body with a distal and a first and a second lumen therethrough; (b) a first at least one opening near the distal end of the elongate body, the first at least one opening in fluid communication with the first lumen; and (c) a second at least one opening proximal to the first at least one opening, the second at least one opening in fluid communication with the second lumen; ii. advancing the device through the vasculature such that the first at least one opening is distal to the thrombus and the second at least one opening is proximal to the thrombus; iii. infusing a first fluid through the first lumen, out the first at least one opening and into the vasculature distal of the thrombus; and iv. infusing a second fluid through the second lumen, out the second at least one opening and into the vasculature proximal of the thrombus.
Claim 2
Independent Claim
174 words
A method of treating thrombus that is lodged in a human vasculature, comprising the steps of: i. providing a device having: (a) an elongate body with a distal and a first and a second lumen therethrough; (b) a first at least one opening near the distal end of the elongate body, the first at least one opening in fluid communication with the first lumen; and (c) a second at least one opening proximal to the first at least one opening, the second at least one opening in fluid communication with the second lumen; ii. advancing the device through the vasculature such that the first at least one opening is distal to the thrombus and the second at least one opening is proximal to the thrombus; iii. infusing a first fluid through the first lumen, out the first at least one opening and into the vasculature distal of the thrombus; and iv. infusing a second fluid through the second lumen, out the second at least one opening and into the vasculature proximal of the thrombus.
Claim 3
Dependent Claim
61 words
The method of treating thrombus as in claim 1 wherein the device includes a core wire having a proximal end and a distal end, the proximal end of the core wire affixed to the elongate body within the first lumen and the distal end of the core wire affixed to the elongate body within a distal end of the first lumen.
Claim 4
Dependent Claim
21 words
The method of treating thrombus as in claim 2 wherein the distal end of the core wire includes an atraumatic tip.
Claim 5
Dependent Claim
77 words
The method of treating thrombus as in claim 2 wherein the first lumen has a proximal portion, a distal portion and an axis and the second lumen has a proximal portion, a distal portion and an axis, the proximal portion of the first lumen disposed coaxial to the proximal portion of the second lumen and the axis of the distal portion of the first lumen disposed adjacent the axis of the distal portion of the second lumen.
Claim 6
Independent Claim
140 words
A method of diagnosing and treating thrombus that is lodged in a human vasculature comprising the steps of: i. providing a device having: (a) an elongate body with a distal end and a first and second lumen therethrough; (b) a first at least one opening near the distal end of the elongate body, the first at least one opening in fluid communication with the first lumen; and (c) a second at least one opening proximal to the first at least one opening, the second at least one opening in fluid communication with the second lumen; ii. advancing the device through the vasculature such that the first at least one opening is embedded in the thrombus; and iii. infusing a thrombolytic agent out of the first at least one opening such that the thrombus is dissolved or broken into small pieces.
Claim 7
Independent Claim
140 words
A method of diagnosing and treating thrombus that is lodged in a human vasculature comprising the steps of: i. providing a device having: (a) an elongate body with a distal end and a first and second lumen therethrough; (b) a first at least one opening near the distal end of the elongate body, the first at least one opening in fluid communication with the first lumen; and (c) a second at least one opening proximal to the first at least one opening, the second at least one opening in fluid communication with the second lumen; ii. advancing the device through the vasculature such that the first at least one opening is embedded in the thrombus; and iii. infusing a thrombolytic agent out of the first at least one opening such that the thrombus is dissolved or broken into small pieces.
Claim 8
Dependent Claim
35 words
The method of diagnosing and treating thrombus as in claim 5 further comprising the step of: infusing a fluid out of the second at least one opening and into the vasculature proximal to the thrombus.
Claim 9
Dependent Claim
18 words
The method of diagnosing and treating thrombus as in claim 6 wherein the fluid is a contrast agent.
Claim 10
Dependent Claim
18 words
The method of diagnosing and treating thrombus as in claim 6 wherein the fluid is a thrombolytic agent.
Claim 11
Dependent Claim
18 words
The method of diagnosing and treating thrombus as in claim 6 wherein the fluid is a neuroprotective agent.
Claim 12
Independent Claim
154 words
A method of diagnosing and treating thrombus that is lodged in a human vasculature comprising the steps of: i. providing a device having; (a) an elongate body with a distal end and a first and second lumen therethrough; (b) a first at least one opening located near the distal end of the elongate body, the first at least one opening in fluid communication with the first lumen; and (c) a second at least one opening located proximal to the first at least one opening, the second at least one opening in fluid communication with the second lumen; ii. advancing the device through the vasculature such that the second at least one opening is embedded in the thrombus and the first at least one opening is distal to the thrombus; and iii. infusing a thrombolytic agent out of the second at least one opening such that the thrombus is dissolved or broken into small pieces.
Claim 13
Independent Claim
154 words
A method of diagnosing and treating thrombus that is lodged in a human vasculature comprising the steps of: i. providing a device having; (a) an elongate body with a distal end and a first and second lumen therethrough; (b) a first at least one opening located near the distal end of the elongate body, the first at least one opening in fluid communication with the first lumen; and (c) a second at least one opening located proximal to the first at least one opening, the second at least one opening in fluid communication with the second lumen; ii. advancing the device through the vasculature such that the second at least one opening is embedded in the thrombus and the first at least one opening is distal to the thrombus; and iii. infusing a thrombolytic agent out of the second at least one opening such that the thrombus is dissolved or broken into small pieces.
Claim 14
Dependent Claim
38 words
The method of diagnosing and treating thrombus as in claim 10 further comprising the step of: infusing a fluid through the first lumen, out the first at least one opening and into the vasculature distal to the thrombus.
Claim 15
Dependent Claim
18 words
The method of diagnosing and treating thrombus as in claim 11 wherein the fluid is a contrast agent.
Claim 16
Dependent Claim
18 words
The method of diagnosing and treating thrombus as in claim 11 wherein the fluid is a thrombolytic agent.
Claim 17
Dependent Claim
18 words
The method of diagnosing and treating thrombus as in claim 11 wherein the fluid is a neuroprotective agent.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-07-20 | 2002-01-19 | 2002-07-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-07-20 | 2006-01-19 | 2006-07-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-07-20 | 2010-01-19 | 2010-07-21 | $7700.00 | Window Closed / Lapsed |