US5545222A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method using human tissue
Assignee: Bonutti Skeletal Innovations LLC
•
Filing: 1994-07-08
•
Granted: 1996-08-13
•
Expires: 2014-07-08
Abstract
Abstract A tissue press for shaping or compressing a piece of tissue comprises first and second members movable relative to each other. Tissue removed from a human body is placed in the press. The press is operated to apply pressure against the human tissue. The human tissue is maintained in a viable living condition during operation of the press. Means are preferably provided for monitoring and controlling the amount of pressure applied to the piece of tissue, in order to maintain the tissue in a viable living condition. Means may also be provided for draining off fluid from compressed tissue, so that the tissue can be implanted in a compressed state and imbibe fluid from the host site. A retainer, which may be expandable, can be used to maintain the tissue graft in a compressed condition.
Inventors
- 👤 Peter M. Bonutti
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:31
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/32; A61F2/36; A61F2/3662; A61B; A61B17/00; A61B17/16; A61B17/1604; A61B17/1606; A61B17/56; A61B17/58; A61B17/88; A61B17/885; A61F2/08; A61F2/28; A61F2/46; A61F2/4644; B; B30; B30B; B30B1/00; B30B1/02; B30B1/04; B30B11/00; B30B11/02; A61B17/04; A61B17/06; A61B17/06166; A61B17/68; A61B17/84; A61B17/86; A61B2017/00004; A61B2017/00535; A61B2017/00539; A61B2017/00544; A61B2017/00969; A61F2/0811; A61F2/3094; A61F2002/2835; A61F2002/2839; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/30062; A61F2002/30075; A61F2002/30108; A61F2002/30199; A61F2002/30224; A61F2002/30316; A61F2002/30535; A61F2002/30537; A61F2002/30545; A61F2002/30579; A61F2210/00; A61F2210/0004; A61F2210/0061; A61F2230/00; A61F2230/0063; A61F2230/0069; A61F2240/00; A61F2240/001; A61F2250/00; A61F2250/0004; A61F2250/001; Y; Y10; Y10S; Y10S623/00; Y10S623/901; Y10S623/902; Y10S623/908; Y10S623/915; Y10S623/919; Y10S623/92
Claims Analysis
Total Claims: 47
Claim 1
Independent Claim
94 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, thereafter, removing the human tissue from the press and, inserting the human tissue removed from the press into a human body, the tissue removed from a human body being maintained in a viable living condition during performance of said steps of operating the press and inserting the tissue into a human body.
Claim 2
Independent Claim
94 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, thereafter, removing the human tissue from the press and, inserting the human tissue removed from the press into a human body, the tissue removed from a human body being maintained in a viable living condition during performance of said steps of operating the press and inserting the tissue into a human body.
Claim 3
Dependent Claim
28 words
A method as set forth in claim 1 further including the step of conducting fluid from the human tissue during performance of said step of operating the press.
Claim 4
Dependent Claim
77 words
A method as set forth in claim 1 wherein said step of operating the press includes shaping the human tissue in the press to a predetermined configuration, said step of inserting the human tissue removed from the press into a human body includes inserting the human tissue removed from the press into an opening in the human body having a configuration which corresponds to the predetermined configuration to which the human tissue is shaped in the press.
Claim 5
Dependent Claim
61 words
A method as set forth in claim 1 wherein said step of removing tissue from a human body includes removing tendon tissue from the human body, said step of placing the tissue removed from the human body in a press includes placing the tendon tissue in the press, said step of operating the press includes applying pressure against the tendon tissue.
Claim 6
Dependent Claim
44 words
A method as set forth in claim 1 wherein said step of removing tissue from the human body includes removing bone tissue and tendon tissue, said step of operating the press includes compressing bone tissue around at least a portion of the tendon tissue.
Claim 7
Dependent Claim
78 words
A method as set forth in claim 1 wherein said step of removing tissue from a human body includes removing skin tissue from the human body, said step of placing the tissue removed from the human body in a press includes supporting the skin tissue with a support surface in the press, said step of operating the press includes applying pressure against the skin tissue while the skin tissue is at least partially supported by the support surface.
Claim 8
Dependent Claim
85 words
A method as set forth in claim 1 wherein said step of removing tissue from a human body includes removing tissue from a plurality of locations in the human body, said step of placing the tissue removed from the human body in a press including the step of placing a plurality of pieces of tissue removed from a plurality of locations in a human body in the press, said step of operating the press includes pressing the plurality of pieces of tissue against each other.
Claim 9
Dependent Claim
57 words
A method as set forth in claim 1 further including placing at least one additional material from a group which consists of antibiotics, bone growth enhancers, tricalcium phosphate, fibrin, allograft material and autograft material in the press with the human tissue, said step of operating the press including pressing the human tissue and the added material together.
Claim 10
Dependent Claim
48 words
A method as set forth in claim 1 wherein said step of operating the press includes forcing fluid out of the human tissue, said step of inserting the human tissue removed from the press into a human body is performed with the human tissue in a defluidized condition.
Claim 11
Dependent Claim
74 words
A method as set forth in claim 1 wherein said step of placing the tissue removed from the human body in a press includes placing the tissue from the human body on a first forming element, said step of operating the press to apply pressure against the human tissue in the press includes moving a second forming element toward the first forming element with the human tissue between the first and second forming elements.
Claim 12
Dependent Claim
37 words
A method as set forth in claim 1 wherein said step of applying pressure against the human tissue by operating the press includes reshaping the exterior configuration of the human tissue without significantly compressing the human tissue.
Claim 13
Dependent Claim
43 words
A method as set forth in claim 1 wherein the human tissue has a first volume when the human tissue is placed in the press and has a volume equal to the first volume when the human tissue is removed from the press.
Claim 14
Dependent Claim
36 words
A method as set forth in claim 1 wherein said step of operating the press includes limiting the maximum pressure which is applied to the human tissue during operation of the press to a predetermined pressure.
Claim 15
Dependent Claim
30 words
A method as set forth in claim 1 further including the step of cutting of excess human tissue from the human tissue while the human tissue is in the press.
Claim 16
Dependent Claim
49 words
A method as set forth in claim 1 wherein said step of removing tissue from a human body includes removing bone tissue from one site and removing tendon tissue from another site, said step of operating the press includes compressing bone tissue around a portion of the tendon tissue.
Claim 17
Dependent Claim
25 words
A method as set forth in claim 1 further including the step of cooling the human tissue while the human tissue is in the press.
Claim 18
Dependent Claim
25 words
A method as set forth in claim 1 further including the step of heating the human tissue while the human tissue is in the press.
Claim 19
Dependent Claim
57 words
A method as set forth in claim 1 further including the step of at least partially enclosing the human tissue with a retainer, said step of inserting the human tissue removed from the press into a human body includes inserting the human tissue into the body with the human tissue at least partially enclosed by the retainer.
Claim 20
Dependent Claim
47 words
A method as set forth in claim 18 further including providing openings in the retainer to enable human tissue to grow through the openings after performing said step of inserting the human tissue into the body with the human tissue at least partially enclosed by the retainer.
Claim 21
Dependent Claim
83 words
A method as set forth in claim 1 further including the step of at least partially enclosing the human tissue with a retainer prior to performing said step of placing the tissue in the press, said step of operating the press to apply pressure against the human tissue includes applying pressure against the human tissue while the human tissue is in the retainer, said step of inserting the human tissue into a human body being performed with the human tissue in the retainer.
Claim 22
Dependent Claim
47 words
A method as set forth in claim 20 further including the step of expanding the retainer and the human tissue in the retainer after performing said step of inserting the human tissue into a human body with the human tissue at least partially enclosed by the retainer.
Claim 23
Dependent Claim
60 words
A method as set forth in claim 1 further including at least partially enclosing the human tissue with a retainer after having performed said step of operating the press to apply pressure against the human tissue, said step of inserting the human tissue into a human body being performed with the human tissue at least partially enclosed by the retainer.
Claim 24
Dependent Claim
47 words
A method as set forth in claim 22 further including the step of expanding the retainer and the human tissue in the retainer after performing said step of inserting the human tissue into a human body with the human tissue at least partially enclosed by the retainer.
Claim 25
Dependent Claim
106 words
A method as set forth in claim 1 further including at least partially enclosing the human tissue with a retainer, said step of inserting the human tissue into a human body includes inserting the human tissue into a human body with the human tissue at least partially enclosed by a retainer, said method further including the step of expanding the retainer outward to engage tissue in the human body and expanding the retainer inward to grip the human tissue in the retainer after performing said step of inserting the human tissue into a human body with the human tissue at least partially enclosed by the retainer.
Claim 26
Independent Claim
125 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body; said step of removing tissue from a human body includes removing skin tissue from the human body; placing the tissue removed from the human body in a press; said step of placing the tissue removed from a human body in a press includes placing the skin tissue and a retaining mesh on a support surface of said press; operating the press to apply pressure against the human tissue in the press; said step of operating the press includes pressing the skin tissue and retaining mesh together; thereafter, removing the human tissue from the press, and inserting the human tissue removed from the press into a human body.
Claim 27
Independent Claim
125 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body; said step of removing tissue from a human body includes removing skin tissue from the human body; placing the tissue removed from the human body in a press; said step of placing the tissue removed from a human body in a press includes placing the skin tissue and a retaining mesh on a support surface of said press; operating the press to apply pressure against the human tissue in the press; said step of operating the press includes pressing the skin tissue and retaining mesh together; thereafter, removing the human tissue from the press, and inserting the human tissue removed from the press into a human body.
Claim 28
Independent Claim
146 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body; said step of removing tissue from a human body includes removing tissue from a plurality of locations in the human body; placing the tissue removed from the human body in a press; said step of placing the tissue removed from the human body in a press including the step of placing a plurality of pieces of tissue removed from a plurality of locations in a human body in the press; operating the press to apply pressure against the human tissue in the press; said step of operating the press including interconnecting the plurality of pieces of tissue by applying pressure against the plurality of pieces of tissue; thereafter, removing the human tissue from the press, and inserting the human tissue removed from the press into a human body.
Claim 29
Independent Claim
146 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body; said step of removing tissue from a human body includes removing tissue from a plurality of locations in the human body; placing the tissue removed from the human body in a press; said step of placing the tissue removed from the human body in a press including the step of placing a plurality of pieces of tissue removed from a plurality of locations in a human body in the press; operating the press to apply pressure against the human tissue in the press; said step of operating the press including interconnecting the plurality of pieces of tissue by applying pressure against the plurality of pieces of tissue; thereafter, removing the human tissue from the press, and inserting the human tissue removed from the press into a human body.
Claim 30
Independent Claim
105 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, thereafter, removing the human tissue from the press, enclosing the human tissue with a retainer, and inserting the human tissue removed from the press into a human body, said step of inserting the human tissue removed from the press into a human body includes inserting the human tissue into the human body with the human tissue at least partially enclosed by the retainer.
Claim 31
Independent Claim
105 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, thereafter, removing the human tissue from the press, enclosing the human tissue with a retainer, and inserting the human tissue removed from the press into a human body, said step of inserting the human tissue removed from the press into a human body includes inserting the human tissue into the human body with the human tissue at least partially enclosed by the retainer.
Claim 32
Dependent Claim
28 words
A method as set forth in claim 27 further including the step of conducting fluid from the human tissue during performance of said step of operating the press.
Claim 33
Dependent Claim
77 words
A method as set forth in claim 27 wherein said step of operating the press includes shaping the human tissue in the press to a predetermined configuration, said step of inserting the human tissue removed from the press into a human body includes inserting the human tissue removed from the press into an opening in the human body having a configuration which corresponds to the predetermined configuration to which the human tissue is shaped in the press.
Claim 34
Dependent Claim
84 words
A method as set forth in claim 27 wherein said step of removing tissue from a human body includes removing tissue from a plurality of locations in the human body, said step of placing the tissue removed from the human body in a press including the step of placing a plurality of pieces of tissue removed from a plurality of locations in a human body in the press, said step of operating the press includes applying pressure against the plurality of pieces of tissue.
Claim 35
Dependent Claim
57 words
A method as set forth in claim 27 further including placing at least one additional material from a group which consists of antibiotics, bone growth enhancers, tricalcium phosphate, fibrin, allograft material and autograft material in the press with the human tissue, said step of operating the press including pressing the human tissue and the added material together.
Claim 36
Dependent Claim
67 words
A method as set forth in claim 27 wherein said step of operating the press includes forcing fluid out of the body tissue, said step of inserting the human tissue removed from the press into a human body is performed with the human tissue in a defluidized condition, said method further including absorbing fluid into the human tissue after it has been inserted into a human body.
Claim 37
Dependent Claim
74 words
A method as set forth in claim 27 wherein said step of placing the tissue removed from the human body in a press includes placing the tissue from the human body on a first forming element, said step of operating the press to apply pressure against the human tissue in the press includes moving a second forming element toward the first forming element with the human tissue between the first and second forming elements.
Claim 38
Dependent Claim
37 words
A method as set forth in claim 27 wherein said step of applying pressure against the human tissue by operating the press includes reshaping the exterior configuration of the human tissue without significantly compressing the human tissue.
Claim 39
Dependent Claim
43 words
A method as set forth in claim 219 wherein the human tissue has a first volume when the human tissue is placed in the press and has a volume equal to the first volume when the human tissue is removed from the press.
Claim 40
Dependent Claim
47 words
A method as set forth in claim 27 further including providing openings in the retainer to enable human tissue to grow through the openings after performing said step of inserting the human tissue into the body with the human tissue at least partially enclosed by the retainer.
Claim 41
Dependent Claim
44 words
A method as set forth in claim 27 further including the step of expanding the human tissue and the retainer after performing said step of inserting the human tissue into a human body with the human tissue at least partially enclosed by the retainer.
Claim 42
Dependent Claim
47 words
A method as set forth in claim 27 further including the step of expanding the retainer and the human tissue in the retainer after performing said step of inserting the human tissue into a human body with the human tissue at least partially enclosed by the retainer.
Claim 43
Independent Claim
89 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, thereafter, at least partially enclosing the human tissue with a retainer after having performed said step of operating the press to apply pressure against the human tissue, removing the human tissue from the press, and inserting the human tissue removed from the press into a human body.
Claim 44
Independent Claim
89 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, thereafter, at least partially enclosing the human tissue with a retainer after having performed said step of operating the press to apply pressure against the human tissue, removing the human tissue from the press, and inserting the human tissue removed from the press into a human body.
Claim 45
Independent Claim
126 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, shaping the human tissue in the press to a predetermined configuration under the influence of the pressure applied against the human tissue by the press during operation of the press, thereafter, removing the human tissue from the press after the human tissue has been shaped to the predetermined configuration in the press by the pressure applied against the human tissue by the press, and inserting the human tissue removed from the press into a human body while the human tissue has the predetermined configuration.
Claim 46
Independent Claim
126 words
A method of using human tissue, said method comprising the steps of removing tissue from a human body, placing the tissue removed from the human body in a press, operating the press to apply pressure against the human tissue in the press, shaping the human tissue in the press to a predetermined configuration under the influence of the pressure applied against the human tissue by the press during operation of the press, thereafter, removing the human tissue from the press after the human tissue has been shaped to the predetermined configuration in the press by the pressure applied against the human tissue by the press, and inserting the human tissue removed from the press into a human body while the human tissue has the predetermined configuration.
Claim 47
Dependent Claim
53 words
A method as set forth in claim 26 wherein said step of removing tissue from a plurality of locations in the human body includes removing bone tissue and tendon tissue, said step of interconnecting the plurality of pieces of tissue includes compressing bone tissue around at least a portion of the tendon tissue.
References Cited (Backward Citations)
DE337437C
Cited
CH117960A
Cited
US1959615A
Cited
US2433815A
Cited
US2724326A
Cited
FR1111677A
Cited
US3048522A
Cited
US2955530A
Cited
US3514791A
Cited
US4304178A
Cited
US4453421A
Cited
US4678470A
Cited
US4863472A
Cited
US4794854A
Cited
US4950296A
Cited
US5101720A
Cited
US5329846A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-08-13 | 2000-02-12 | 2000-08-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-08-13 | 2004-02-12 | 2004-08-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-08-13 | 2008-02-12 | 2008-08-13 | $7700.00 | Window Closed / Lapsed |