Human IL-2 receptor γ chain molecule

Claim 2

Isolated and purified DNA having a nucleotide sequence coding for human interleukin-2 receptor γ-chain, selected from the group consisting of: (a) sequence Id Nos. 1, 2, 3, 5, 6, 8 and 10; and (b) altered nucleotide sequences of (a) due to degeneracy in the genetic code.

Claim 3

Isolated and purified DNA having a nucleotide sequence according to claim 1, which is represented by the following nucleotide sequence: (Seq. Id. No. 10) __________________________________________________________________________ CTG AAC ACG ACA ATT CTG ACG CCC AAT GGG AAT GAA GAC ACC ACA 48T GAT TTC TTC CTG ACC ACT ATG CCC ACT GAC TCC CTC AGC GTT TCC 96T CTG CCC CTC CCA GAG GTT CAG TGT TTT GTG TTC AAT GTC GAG TAC 144 AAT TGC ACT TGG AAC AGC AGC TCT GAG CCC CAG CCT ACC AAC CTC 192 CTG CAT TAT TGG TAC AAG AAC TCG GAT AAT GAT AAA GTC CAG AAG 240 AGC CAC TAT CTA TTC TCT GAA GAA ATC ACT TCT GGC TGT CAG TTG 288 AAA AAG GAG ATC CAC CTC TAC CAA ACA TTT GTT GTT CAG CTC CAG 336 CCA CGG GAA CCC AGG AGA CAG GCC ACA CAG ATG CTA AAA CTG CAG 384 CTG GTG ATC CCC TGG GCT CCA GAG AAC CTA ACA CTT CAC AAA CTG 432 GAA TCC CAG CTA GAA CTG AAC TGG AAC AAC AGA TTC TTG AAC CAC 480 TTG GAG CAC TTG GTG CAG TAC CGG ACT GAC TGG GAC CAC AGC TGG 528 GAA CAA TCA GTG GAT TAT AGA CAT AAG TTC TCC TTG CCT AGT GTG 576 GGG CAG AAA CGC TAC ACG TTT CGT GTT CGG AGC CGC TTT AAC CCA 624 TGT GGA AGT GCT CAG CAT TGG AGT GAA TGG AGC CAC CCA ATC CAC 672 GGG AGC AAT ACT TCA AAA TAG 693 __________________________________________________________________________

Claim 4

Isolated and purified DNA having a nucleotide sequence according to claim 1, which is represented by the following nucleotide sequence: (Seq. Id. No. 8) __________________________________________________________________________ ATG TTG AAG CCA TCA TTA CCA TTC ACA TCC CTC TTA TTC CTG CAG 48G CCC CTG CTG GGA GTG GGG CTG AAC ACG ACG ATT CTG ACG CCC AAT 96G AAT GAA GAC ACC ACA GCT GAT TTC TTC CTG ACC ACT ATG CCC ACT 144 TCC CTC AGC GTT TCC ACT CTG CCC CTC CCA GAG GTT CAG TGT TTT 192 TTC AAT GTC GAG TAC ATG AAT TGC ACT TGG AAC AGC AGC TCT GAG 240 CAG CCT ACC AAC CTC ACT CTG CAT TAT TGG TAC AAG AAC TCG GAT 288 GAT AAA GTC CAG AAG TGC AGC CAC TAT CTA TTC TCT GAA GAA ATC 336 TCT GGC TGT CAG TTG CAA AAA AAG GAG ATC CAC CTC TAC CAA ACA 384 GTT GTT CAG CTC CAG GAC CCA CGG GAA CCC AGG AGA CAG GCC ACA 432 ATG CTA AAA CTG CAG AAT CTG CTG ATC CCC TGG GCT CCA GAG AAC 480 ACA CTT CAC AAA CTG AGT GAA TCC CAG CTA GAA CTG AAC TGG AAC 528 AGA TTC TTG AAC CAC TGT TTG GAG CAC TTG GTG CAG TAC CGG ACT 576 TGG GAC CAC AGC TGG ACT GAA CAA TCA GTG GAT TAT AGA CAT AAG 624 TCC TTG CCT AGT GTG GAT GGG CAG AAA CGC TAC ACG TTT CGT GTT 672 AGC CGC TTT AAC CCA CTC TGT GGA AGT GCT CAG CAT TGG AGT GAA 720 AGC CAC CCA ATC CAC TGG GGG AGC AAT ACT TCA AAA TAG 759 __________________________________________________________________________

Claim 5

Isolated and purified DNA having a nucleotide sequence according to claim 1, which is represented by the following nucleotide sequence: (Seq. Id. No. 6) __________________________________________________________________________ CTG AAC ACG ACA ATT CTG ACG CCC AAT GTG AAT GAA GAC ACC ACA 48T GAT TTC TTC CTG ACC ACT ATG CCC ACT GAC TCC CTC AGC GTT TCC 96T CTG CCC CTC CCA GAG GTT CAG TGT TTT GTG TTC AAT GTC GAG TAC 144 AAT TGC ACT TGG AAC AGC AGC TCT GAG CCC CAG CCT ACC AAC CTC 192 AAT TGC ACT TGG AAC AGC AGC TCT GAG CCC CAG CCT ACC AAC CTC 192 CTG CAT TAT TGG TAC AAG AAC TCT GAT AAT GAT AAA GTC CAG AAG 240 AGC CAC TAT CTA TTC TCT GAA GAA ATC ACT TCT GGC TGT CAG TTG 288 AAA AAG GAG ATC CAC CTC TAC CAA ACA TTT GTT GTT CAG CTC CAG 336 CCA CGG GAA CCC AGG AGA CAG GCC ACA CAG ATG CTA AAA CTG CAG 384 CTG GTG ATC CCC TGG GCT CCA GAG AAC CTA ACA CTT CAC AAA CTG 432 GAA TCC CAG CTA GAA CTG AAC TGG AAC AAC AGA TTC TTG AAC CAC 480 TTG GAG CAC TTG GTG CAG TAC CGG ACT GAC TGG GAC CAC AGC TGG 528 GAA CAA TCA GTG GAT TAT AGA CAT AAG TTC TCC TTT CCT AGT GTG 576 GGG CAG AAA CGC TAC ACG TTT CCT GTT CGG AGC CGC TTT AAC CCA 624 TGT GGA AGT GCT CAG CAT TGG AGT GAA TGG AGC CAC CCA ATC CAC 672 GGG AGC AAT ACT TCA AAA GAG AAT CCT TTC CTG TTT GCA TTG GAA 720 GTG GTT ATC TCT GTT GGC TCC ATG GGA TTG ATT ATC AGC CTT CTC 768 GTG TAT TTC TGG CTG GAA CGG ACG ATG CCC CGA ATT CCC ACC CTG 816 AAC CTA GAG GAT CTT GTT ACT GAA TAC CAC GGG AAC TTT TCG GCC 864 AGT GGT GTG TCT AAG GGA CTG GCT GAG AGT CTG CAG CCA GAC TAC 912 GAA CGA CTC TGC CTC GTC AGT GAG ATT CCC CCA AAA GGA GGG GCC 960 GGG GAG GGG CCT GGG GCC TCC CCA TGC AAC CAG CAT AGC CCC TAC 1008 GCC CCC CCA TGT TAC ACC CTA AAG CCT GAA ACC TGA 1044 __________________________________________________________________________

Claim 6

Isolated and purified DNA having a nucleotide sequence according to claim 1, which is represented by the following nucleotide sequence: (Seq. Id. No. 5) __________________________________________________________________________ ATG TTG AAG CCA TCA TTA CCA TTC ACA TCC CTC TTA TTC CTG CAG 48G CCC CTG CTG GGA GTG GGG CTG AAC ACG ACA ATT CTG ACG CCC AAT 96G AAT GAA GAC ACC ACA GCT GAT TTC TTC CTG ACC ACT ATG CCC ACT 144 TCC CTC AGC GTT TCC ACT CTG CCC CTC CCA GAG GTT CAG TGT TTT 192 TTC AAT GTC GAG TAC ATG AAT TGC ACT TGG AAC AGC AGC TCT GAG 240 CAG CCT ACC AAC CTC ACT CTG CAT TAT TGG TAC AAG AAC TCG GAT 288 GAT AAA GTC CAG AAG TGC AGC CAC TAT CTA TTC TCT GAA GAA ATC 336 TCT GGC TGT CAG TTG CAA AAA AAG GAG ATC CAC CTC TAC CAA ACA 384 GTT GTT CAG CTC CAG GAC CCA CGG GAA CCC AGG AGA CAG GCC ACA 432 ATG CTA AAA CTG CAG AAT CTG GTG ATC CCC TGG GCT CCA GAG AAC 480 ACA CTT CAC AAA CTG AGT GAA TCC CAG CTA GAA CTG AAC TGG AAC 528 AGA TTC TTG AAC CAC TGT TTG GAG CAC TTG GTG CAG TAC CGG ACT 576 TGG GAC CAC AGC TGG ACT GAA CAA TCA GTG GAT TAT AGA CAT AAG 624 TCC TTG CCT AGT GTG GAT GGG CAG AAA CGC TAC ACG TTT CGT GTT 672 AGC CGC TTT AAC CCT CTC TCT GGA AGT GCT CAG CAT TGG AGT GAA 720 AGC CAC CCA ATC CAC TGG GGG AGC AAT ACT TCA AAA GAG AAT CCT 768 CTG TTT GCA TTG GAA GCC GTG GTT ATC TCT GTT GGC TCC ATG GGA 816 ATT ATC AGC CTT CTC TGT GTG TAT TTC TGG CTG GAA CGG ACG ATG 864 CGA ATT CCC ACC CTG AAG AAC CTA GAG GAT CTT GTT ACT GAA TAC 912 GGG AAC TTT TCG GCC TGG AGT GGT GTG TCT AAG GGA CTG GCT GAG 960 CTG CAG CCA GAC TAC AGT GAA CGA CTC TGC CTC GTC AGT GAG ATT 1008 CCA AAA GGA GGG GCC CTT GGG GAG GGG CCT GGG GCC TCC CCA TGC 1056 CAG CAT AGC CCC TAC TGG GCC CCC CCA TGT TAC ACC CTA AAG CCT 1104 ACC TGA 1110 __________________________________________________________________________

Claim 7

A vector comprising DNA according to claim 1.

Claim 8

A vector according to claim 6, which is an expression vector.

Claim 9

A vector according to claim 6, which can be propagated in an eucaryotic cell.

Claim 10

A vector according to claim 6, which can be propagated in an procaryotic cell.

Claim 11

A cell transformed with a vector according to claim 6.

Claim 12

A cell according to claim 10, which is FERM BP-4199.

Claim 13

A cell according to claim 10, which is FERM BP-4200.

Claim 14

A cell transformed with DNA according to claim 1.

Claim 15

A cell according to claim 13, which is an eucaryotic cell.

Claim 16

A cell according to claim 13, which is an procaryotic cell.

Claim 17

A cell according to claim 14, which is a CHO cell.

Claim 18

A cell according to claim 14, which is a mouse L929 cell.

Claim 19

A cell according to claim 15, which is of the genus E. coli.