US5464439A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction
Assignee: GENDLER EL AND GENDLER SIMONA TRUSTEES OF GENDLER LIVING TRUST ESTABLISHED DECEMBER 24 1992
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Filing: 1993-11-12
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Granted: 1995-11-07
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Expires: 2013-11-12
Abstract
Abstract A flexible, organic bone matrix which is adapted for use during the in vivo repair, replacement or reformation of preselected portions of a mammalian or animal skeletal system comprising a continuous sheet of completely or partially demineralized natural bone, wherein the thickness of said sheet is such that the sheet has sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The matrix is ultimately resorbed by the body thereby eliminating the need for supplemental surgery to remove the matrix, as is presently necessary when other exogenous, membrane materials are used. A method for the in vivo repair or replacement of a preselected section of a mammalian or animal skeletal system utilizing said matrix is also disclosed.
Inventors
- 👤 El Gendler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:33
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3608; A61F; A61F2/00; A61F2/02; A61F2/28; A61L27/3641; A61L27/3645; A61L27/365; A61L27/3683; A61L27/3695; A61F2/30; A61F2002/30001; A61F2002/30003; A61F2002/30004; A61F2002/30059; A61F2002/3006; A61F2002/30062; A61F2210/00; A61F2210/0004; Y; Y10; Y10S; Y10S623/00; Y10S623/902; Y10S623/908; Y10S623/915; Y10S623/919
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
89 words
A method for the in vivo repair or replacement of a preselected section of an animal skeletal system comprising affixing demineralized natural bone formed into a continuous sheet to the section, wherein the thickness of said sheet is such that the sheet has sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet, said thickness being less than about 1.5 millimeters.
Claim 2
Independent Claim
89 words
A method for the in vivo repair or replacement of a preselected section of an animal skeletal system comprising affixing demineralized natural bone formed into a continuous sheet to the section, wherein the thickness of said sheet is such that the sheet has sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet, said thickness being less than about 1.5 millimeters.
Claim 3
Dependent Claim
25 words
The method of in vivo repair and replacement of claim 1, wherein the thickness of said sheet ranges from about 0.05 to about 1.5 millimeters.
Claim 4
Dependent Claim
25 words
The method of in vivo repair and replacement of claim 1, wherein the thickness of said sheet ranges from about 0.7 to about 1.2 millimeters.
Claim 5
Independent Claim
83 words
A method for the in vivo reformation of a mammalian skeletal system comprising inserting demineralized natural bone formed into a continuous sheet into said mammal, wherein the thickness of said sheet is such that the sheet has sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet, said thickness being less than about 1.5 millimeters.
Claim 6
Independent Claim
83 words
A method for the in vivo reformation of a mammalian skeletal system comprising inserting demineralized natural bone formed into a continuous sheet into said mammal, wherein the thickness of said sheet is such that the sheet has sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet, said thickness being less than about 1.5 millimeters.
Claim 7
Dependent Claim
23 words
The method of in vivo reformation of claim 4, wherein the thickness of said sheet ranges from about 0.05 to about 1.5 millimeters.
Claim 8
Dependent Claim
23 words
The method of in vivo reformation of claim 4, wherein the thickness of said sheet ranges from about 0.7 to about 1.2 millimeters.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-11-06 | 1999-05-08 | 1999-11-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-11-06 | 2003-05-08 | 2003-11-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-11-06 | 2007-05-08 | 2007-11-07 | $7700.00 | Window Closed / Lapsed |