Patent US5441491A successfully refreshed from Google Patents.
US5441491A
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Method and composition for treating biopsy wounds
Assignee: Individual
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Filing: 1994-02-04
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Granted: 1995-08-15
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Expires: 2014-02-04
Abstract
Abstract A method and composition for treating biopsy wounds in human patients is provided. The process involves filling the wound with a disc of collagenous material coated with elastine, with the disc of material being of a size to substantially fill the biopsy wound. The collagenous material is preferably derived from the skin of hoofed animals such as calves, sheep and pigs. The disc is combined with a microporous top layer, preferably polyether urethane. This combination is easy to apply and leads to hemostasis, improved wound healing and less wound contraction and scarring.
Inventors
- 👤 Jacob Verschoor
- 👤 Wiete Westerhof
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:17
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/32; A61L15/325; A61L15/26; A61L15/42; A61L15/425
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
46 words
A method of treating a biopsy wound in a human patient comprising: filling said wound with a disc of fibrous collaqenous tissue material from which non-fibrous tissue proteins and glycoproteins as well as lipids and lipid residues have been removed and which has been crosslinked chemically.
Claim 2
Independent Claim
46 words
A method of treating a biopsy wound in a human patient comprising: filling said wound with a disc of fibrous collaqenous tissue material from which non-fibrous tissue proteins and glycoproteins as well as lipids and lipid residues have been removed and which has been crosslinked chemically.
Claim 3
Dependent Claim
25 words
The method of claim 1 wherein the collagenous material contains from about 1% to about 20 wt. % of elastine, based on the collagenous material.
Claim 4
Dependent Claim
25 words
The method of claim 1 wherein the collagenous material contains from about 1% to about 5% by weight of elastine, based on the collagenous material.
Claim 5
Dependent Claim
38 words
The method of claim 1 wherein said disc is first punched from a sheet of collagenous material with the aid of a same-dimension needle which has been used for taking the biopsy punch in creating the biopsy wound.
Claim 6
Dependent Claim
30 words
The method of claim 1 wherein the exterior surface of the disc opposite the wound contact side is covered with a porous membrane to prevent microorganisms from infecting the wound.
Claim 7
Dependent Claim
23 words
The method of claim 1 wherein the disc of collagen material is derived from the skin of calves not older than six months.
Claim 8
Dependent Claim
23 words
The method of claim 6 wherein substantially all of the telopeptides responsible for the antigenicity of collagen are removed by mild chemical treatment.
Claim 9
Dependent Claim
16 words
The method of claim 6 wherein the collagen discs achieve hemostasis in less than 4 minutes.
Claim 10
Dependent Claim
20 words
Discs for treating biopsy wounds comprised of: collagenous material of which the collagen fibers are coated with alpha hydrolysate elastine.
Claim 11
Dependent Claim
20 words
Discs for treating biopsy wounds comprised of: collagenous material of which the collagen fibers are coated with alpha hydrolysate elastine.
Claim 12
Dependent Claim
22 words
The discs of claim 9 which centain from about 1% to about 5% by weight of elastine based on the collagenous material.
Claim 13
Dependent Claim
24 words
The discs of claim 10 which contain from about 1% by weight to about 3% by weight of elastine based on the collagenous material.
Claim 14
Dependent Claim
44 words
Packaged collagen discs comprising: a plurality of discs for treating biopsy wounds, each of said discs being comprised of a collagenous material coated with alpha hydrolysate form of elastine, said plurality of discs having a microporous top layer and packaged in a sterile way.
Claim 15
Dependent Claim
44 words
Packaged collagen discs comprising: a plurality of discs for treating biopsy wounds, each of said discs being comprised of a collagenous material coated with alpha hydrolysate form of elastine, said plurality of discs having a microporous top layer and packaged in a sterile way.
Claim 16
Dependent Claim
20 words
The packaged discs of claim 12 wherein said discs are combined with a 0.3 to 1.0 micron microporous top layer.
Claim 17
Dependent Claim
18 words
The packaged discs of claim 13 wherein the microporous top layer is a membrane made of polyether urethane.
Claim 18
Dependent Claim
22 words
The packaged discs of claim 14 wherein the discs contain from about 1% by weight to about 5% by weight of elastine.
Claim 19
Dependent Claim
28 words
The packaged discs of claim 15 wherein the top layer membrane is shaped in the form of a disc, overlapping the collagen disc with at least one millimeter.
Claim 20
Dependent Claim
25 words
The packaged discs of claim 16 wherein the discs are combined with an adhesive material in order to fixate the combination into the wound bed.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-08-14 | 1999-02-13 | 1999-08-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-08-14 | 2003-02-13 | 2003-08-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-08-14 | 2007-02-13 | 2007-08-15 | $7700.00 | Window Closed / Lapsed |