Device and method for multi-phase radio-frequency ablation

Claim 2

A radio-frequency ablation apparatus for biological tissues, comprising: an electrode catheter having an array of electrodes; and means for supplying individual phased RF voltages to each of said plurality of electrodes, such that, over a predetermined period of time, substantial potential difference exists between substantially any two electrodes of said array of electrodes and to effect RF heating therebetween in order to achieve uniform ablation of biological tissues adjacent to said array of electrodes.

Claim 3

A radio-frequency ablation apparatus for biological tissues as in claim 1, wherein: the diameter of a smaller electrode is greater than 0.7 times that of a larger electrode in the array.

Claim 4

A radio-frequency ablation apparatus for biological tissues as in claim 1, wherein: an array coverage area is defined by the span of said array of electrodes, and an electrode contact area is defined by the contact area said electrode made with a biological tissue; and the sum of all electrodes' contact areas is greater than 0.2 times that of the array coverage area.

Claim 5

A radio-frequency ablation apparatus for biological tissues as in claim 1, wherein: the average distance between the electrodes in the array is less than 2.5 times the average diameter of the electrodes in the array.

Claim 6

A radio-frequency ablation apparatus for biological tissues as in claim 1, further comprising: a temperature sensor in said array of electrodes for sensing temperature of ablation; and means for regulating said individual phased RF voltages in response to said temperature sensing in order to maintain a predetermined temperature of ablation.

Claim 7

A radio-frequency ablation apparatus for biological tissues, comprising: an electrode catheter having an array of electrodes; a plurality of adjacent electrode pairs among said array of electrodes, each formed by an electrode and one of its immediate neighboring electrodes; and means for supplying phased RF voltages to each of said plurality of adjacent electrode pairs, such that, over a predetermined period of time, substantial potential differences exist between each adjacent electrode pair to effect RF heating therebetween in order to achieve uniform ablation of biological tissues adjacent to said array of electrodes.

Claim 8

A radio-frequency ablation apparatus for biological tissues, comprising: an electrode catheter having an array of electrodes; a plurality of adjacent electrode pairs among said array of electrodes, each formed by an electrode and one of its immediate neighboring electrodes; and means for supplying phased RF voltages to each of said plurality of adjacent electrode pairs, such that, over a predetermined period of time, substantial potential differences exist between each adjacent electrode pair to effect RF heating therebetween in order to achieve uniform ablation of biological tissues adjacent to said array of electrodes.

Claim 9

A radio-frequency ablation apparatus for biological tissues as in claim 6, wherein: the diameter of a smaller electrode is greater than 0.7 times that of a larger electrode in the array.

Claim 10

A radio-frequency ablation apparatus for biological tissues as in claim 6, wherein: an array coverage area is defined by the span of said array of electrodes, and an electrode contact area is defined by the contact area said electrode made with a biological tissue; and the sum of all electrodes' contact areas is greater than 0.2 times that of the array coverage area.

Claim 11

A radio-frequency ablation apparatus for biological tissues as in claim 6, wherein: the average distance between the electrodes in the array is less than 2.5 times the average diameter of the electrodes in the array.

Claim 12

A radio-frequency ablation apparatus for biological tissues as in claim 6, further comprising: a temperature sensor in said array of electrodes for sensing temperature of ablation; and means for regulating said individual phased RF voltages in response to said temperature sensing in order to maintain a predetermined temperature of ablation.

Claim 13

A radio-frequency ablation apparatus for biological tissues, comprising: an electrode catheter having an array of five electrodes constituting first and second pairs of spaced-apart electrodes and an odd electrode, said first and second pairs of electrodes being disposed in substantially a cross configuration, and the odd electrode being disposed centrally at the cross configuration; a radio-frequency energy source for providing two-phase voltages over a first pole, a second pole and a common pole; means for connecting said first pole to said first pair of electrodes, and connecting said second pole to said second pair of electrodes, and connecting said common pole to said odd electrode; and means for regulating said radio-frequency power source to provide said two-phase voltages with a predetermined frequency, voltage and phase difference such that, over a predetermined period of time, substantial potential differences exist between said odd central electrode and said first and second pairs of electrodes as well as between said first and second pairs of electrodes to effect RF heating therebetween in order to achieve uniform ablation of biological tissues adjacent said array of five electrodes.

Claim 14

A radio-frequency ablation apparatus for biological tissues, comprising: an electrode catheter having an array of five electrodes constituting first and second pairs of spaced-apart electrodes and an odd electrode, said first and second pairs of electrodes being disposed in substantially a cross configuration, and the odd electrode being disposed centrally at the cross configuration; a radio-frequency energy source for providing two-phase voltages over a first pole, a second pole and a common pole; means for connecting said first pole to said first pair of electrodes, and connecting said second pole to said second pair of electrodes, and connecting said common pole to said odd electrode; and means for regulating said radio-frequency power source to provide said two-phase voltages with a predetermined frequency, voltage and phase difference such that, over a predetermined period of time, substantial potential differences exist between said odd central electrode and said first and second pairs of electrodes as well as between said first and second pairs of electrodes to effect RF heating therebetween in order to achieve uniform ablation of biological tissues adjacent said array of five electrodes.

Claim 15

A radio-frequency ablation apparatus for biological tissues as in claim 11, wherein: the phase difference between said two-phase voltages is in the range of 70° to 110 degrees.

Claim 16

A radio-frequency ablation apparatus for biological tissues as in claim 11, wherein: the diameter of a smaller electrode is greater than 0.7 times that of a larger electrode in the array.

Claim 17

A radio-frequency ablation apparatus for biological tissues as in claim 11, wherein: an array coverage area is defined by the span of said array of five electrodes, and an electrode contact area is defined by the contact area said electrode made with a biological tissue; and the sum of all electrodes' contact areas is greater than 0.2 times that of the array coverage area.

Claim 18

A radio-frequency ablation apparatus for biological tissues as in claim 11, wherein: the average distance between the electrodes in the array is less than 2.5 times the average diameter of the electrodes in the array.

Claim 19

A radio-frequency ablation apparatus for biological tissues as in claim 11, further comprising: a temperature sensor in said array of five electrodes for sensing temperature of ablation; and means for regulating said individual phased RF voltages in response to said temperature sensing in order to maintain a predetermined temperature of ablation.

Claim 22

A method of ablating biological tissues as in claim 17, wherein: the diameter of a smaller electrode is greater than 0.7 times that of a larger electrode in the array.

Claim 23

A method of ablating biological tissues as in claim 17, wherein: an array coverage area is defined by the span of the deployed electrode array, and an electrode contact area is defined by the contact area said electrode made with a biological tissue; and the sum of all electrodes' contact areas is greater than 0.2 times that of the array coverage area.

Claim 24

A method of ablating biological tissues as in claim 17, wherein: the average distance between the electrodes in the array is less than 2.5 times the average diameter of the electrodes in the array.

Claim 25

A method of ablating biological tissues as in claim 17, further comprising the steps of: sensing the temperature during ablation by one or more temperature sensors among the electrode array; and regulating said individual phased RF voltages in response to said temperature sensing in order to maintain a predetermined temperature of ablation.

Claim 26

A method of ablating biological tissues as in claim 17, further comprising the steps of: successively ablating adjacent areas in the biological tissues by the method thereof until a lesion of predetermined size is created.