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US5334698A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for producing polyesters by fermentation: a process for producing optically active carboxylic acids and esters: articles of manufacture comprising polyester

Assignee: University of Groningen
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Filing: 1991-10-02
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Granted: 1994-08-02
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Expires: 2011-10-02
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Abstract

Abstract This invention relates to a process for producing polyester biopolymers by culturing Pseudomonas oleovorans bacteria on substrates comprising certain nutrients. The nature of the polyesters can be varied by varying the nature of the carbon source used. In this way polyesters with unsaturated double bonds can be produced, too. From the polyesters, optically active carboxylic acids or esters are produced. The polymers can be used for making articles of manufacture, such as sutures, films, skin and bone grafts.

Inventors

  • 👤 Bernard Witholt
  • 👤 Roland G. Lageveen

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:04
CPC Classifications
C; C12; C12P; C12P7/00; C12P7/62; C12P7/625; C08; C08G; C08G63/00; C08G63/02; C08G63/06; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/874

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 83 words
An optically active polyester compound isolated from Pseudomonas oleovorans cells cultured in a nutrient medium in the presence of a carbon source and at least one nutrient essential for growth, said carbon source comprising at least one paraffin product containing 6-7 or 9-12 carbon atoms or at least one paraffin oxidation product containing 6-12 carbon atoms, said polyester compound comprising units other than exclusively 3-hydroxyoctanoate units or 3-hydroxyoctanoate and 3-hydroxyhectanoate units having the structural formula: ##STR4## wherein m represents an integer of 2-8.
Claim 2
Dependent Claim 83 words
An optically active polyester compound isolated from Pseudomonas oleovorans cells cultured in a nutrient medium in the presence of a carbon source and at least one nutrient essential for growth, said carbon source comprising at least one paraffin product containing 6-7 or 9-12 carbon atoms or at least one paraffin oxidation product containing 6-12 carbon atoms, said polyester compound comprising units other than exclusively 3-hydroxyoctanoate units or 3-hydroxyoctanoate and 3-hydroxyhectanoate units having the structural formula: ##STR4## wherein m represents an integer of 2-8.
Claim 3
Dependent Claim 15 words
An article of manufacture made from an optically active polyester compound according to claim 1.
Claim 4
Dependent Claim 21 words
The article according to claim 2 wherein said article is a suture, a film, a skin graft or a bone graft,
Claim 5
Dependent Claim 87 words
An optically active polyester compound isolated from Pseudomonas oleovorans cells cultured in a nutrient medium in the presence of a carbon source and at least one nutrient essential for growth, said carbon source comprising at least one compound selected from unbranched 1-olefins containing 7-12 carbon atoms and optionally one or more non-branched paraffins or paraffin oxidation products containing 6-12 carbon atoms, said polyester compound comprising units having the structural formula (1): ##STR5## and units having the structural formula (2): ##STR6## wherein m represents an integer of 2-8.
Claim 6
Dependent Claim 87 words
An optically active polyester compound isolated from Pseudomonas oleovorans cells cultured in a nutrient medium in the presence of a carbon source and at least one nutrient essential for growth, said carbon source comprising at least one compound selected from unbranched 1-olefins containing 7-12 carbon atoms and optionally one or more non-branched paraffins or paraffin oxidation products containing 6-12 carbon atoms, said polyester compound comprising units having the structural formula (1): ##STR5## and units having the structural formula (2): ##STR6## wherein m represents an integer of 2-8.
Claim 7
Dependent Claim 15 words
An article of manufacture made from an optically active polyester compound according to claim 4.
Claim 8
Dependent Claim 21 words
The article according to claim 5 wherein said article is a suture, a film, a skin graft or a bone graft.

References Cited (Backward Citations)

US4477654A Cited
US5023316A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-08-01 1998-01-31 1998-08-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-08-01 2002-01-31 2002-08-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-08-01 2006-01-31 2006-08-02 $7700.00 Window Closed / Lapsed

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