US5282857A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Gel-filled implants
Assignee: Allergan Inc
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Filing: 1992-04-13
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Granted: 1994-02-01
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Expires: 2012-04-13
Abstract
Abstract This invention relates to a medical implant, which comprises an outer envelope and a gel filler material, wherein the gel comprises water and a cellulose gelling agent. The gel in the implant may further contain a lubricating agent. The components of the gel are a biocompatible and do not adversely affect human beings. Implants containing the lubricating agent have a decreased tendency of failure caused by internal friction on the envelope. The implants of the present invention have similar characteristics of the human breast.
Inventors
- 👤 Larry C. Perry
- 👤 G. Patrick Maxwell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:26
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/20
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
83 words
A sealed implantable prosthesis for implantation into soft tissue for replacing or augmenting the tissues, comprising an outer envelope forming a hollow sealed shell defining an enclosed volume, said hollow shell being filled with a gel filler with predetermined density which is a mixture of water and of a cellulose derivative selected from the group consisting of methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl, ethylcellulose, sodium caroboxymethylcellulose, and sodium carboxymethyl, hydroxyethylcellulose and which is retained in said sealed shell to maintain constant its predetermined density.
Claim 2
Dependent Claim
83 words
A sealed implantable prosthesis for implantation into soft tissue for replacing or augmenting the tissues, comprising an outer envelope forming a hollow sealed shell defining an enclosed volume, said hollow shell being filled with a gel filler with predetermined density which is a mixture of water and of a cellulose derivative selected from the group consisting of methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl, ethylcellulose, sodium caroboxymethylcellulose, and sodium carboxymethyl, hydroxyethylcellulose and which is retained in said sealed shell to maintain constant its predetermined density.
Claim 3
Dependent Claim
26 words
An implantable prosthesis according to claim 1, wherein said water is present in the gel in an amount greater than 70% by weight of the gel.
Claim 4
Dependent Claim
25 words
An implantable prosthesis according to claim 2, wherein the water is present in an amount of 75% to about 95% by weight of the gel.
Claim 5
Dependent Claim
26 words
An implantable prosthesis according to claim 2, wherein said cellulose derivative is present in an amount of 0.5% to about 15% by weight of the gel.
Claim 6
Dependent Claim
35 words
An implantable prosthesis according to claim 1, wherein the water is present in the gel in a major amount so that the volume of the gel is determined substantially by the volume of the water.
Claim 7
Dependent Claim
22 words
An implantable prosthesis according to claim 1, wherein the gel essentially consists of a mixture of water and of the cellulose derivative.
Claim 8
Dependent Claim
26 words
An implantable prosthesis according to claim 2, wherein the cellulose derivative is present in an amount from about 0.5% to about 8% by weight of gel.
Claim 9
Dependent Claim
22 words
An implantable prosthesis according to claim 1, wherein the gel has a density from about 0.8 to about 1.5 g/cm 3 .
Claim 10
Dependent Claim
15 words
The implant of claim 1 wherein the cellulose cellulose derivative is hydroxyethylcellulose, hydroxypropylcellulose or methylcellulose.
Claim 11
Dependent Claim
12 words
The implant of claim 1 wherein the envelope is a medical-grade elastomer.
Claim 12
Dependent Claim
12 words
The implant of claim 1 wherein the envelope is a medical-grade silicon.
Claim 13
Dependent Claim
10 words
The implant of claim 1 further comprising a lubricating agent.
Claim 14
Dependent Claim
14 words
The implant of claim 12 wherein the lubricating agent is a polyol lubricating agent.
Claim 15
Dependent Claim
13 words
The implant of claim 12 wherein the lubricating agent is propyleneglycol or glycerol.
Claim 16
Independent Claim
101 words
A method of augmenting or reconstructing a human breast, comprising the steps of subcutaneously implanting a sealed medical prosthesis into a human being, wherein the prosthesis comprises an outer envelope forming a hollow sealed shell defining an enclosed volume and a gel filler with predetermined density in said outer envelope, wherein the gel is a mixture of water and a cellulose gelling agent selected from the group consisting of methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl, ethylcellulose, sodium caroboxymethylcellulose, and sodium carboxymethyl, hydroxyethylcellulose, and wherein said shell is sealed to contain the gel within the medical prostheses and maintain constant said predetermined density.
Claim 17
Independent Claim
101 words
A method of augmenting or reconstructing a human breast, comprising the steps of subcutaneously implanting a sealed medical prosthesis into a human being, wherein the prosthesis comprises an outer envelope forming a hollow sealed shell defining an enclosed volume and a gel filler with predetermined density in said outer envelope, wherein the gel is a mixture of water and a cellulose gelling agent selected from the group consisting of methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl, ethylcellulose, sodium caroboxymethylcellulose, and sodium carboxymethyl, hydroxyethylcellulose, and wherein said shell is sealed to contain the gel within the medical prostheses and maintain constant said predetermined density.
Claim 18
Independent Claim
108 words
A method of preparing medical implantable completely sealed prostheses, comprising the steps of mixing water and a cellulose derivative selected from the group consisting of methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl, ethylcellulose, sodium caroboxymethylcellulose, and sodium carboxymethyl, hydroxyethylcellulose to form a gel filler with predetermined density in which water is present in a major amount, filling with said gel filler an outer envelope of a medical-grade elastomer forming a hollow shell providing a substantially sealed internal surface to the gel, and sealing the outer envelope to form a medical implantable prosthesis in which the gel filter is retained and its predetermined density is maintained constant within the sealed envelope.
Claim 19
Independent Claim
108 words
A method of preparing medical implantable completely sealed prostheses, comprising the steps of mixing water and a cellulose derivative selected from the group consisting of methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl, ethylcellulose, sodium caroboxymethylcellulose, and sodium carboxymethyl, hydroxyethylcellulose to form a gel filler with predetermined density in which water is present in a major amount, filling with said gel filler an outer envelope of a medical-grade elastomer forming a hollow shell providing a substantially sealed internal surface to the gel, and sealing the outer envelope to form a medical implantable prosthesis in which the gel filter is retained and its predetermined density is maintained constant within the sealed envelope.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-01-31 | 1997-08-02 | 1998-02-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-01-31 | 2001-08-02 | 2002-02-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-01-31 | 2005-08-02 | 2006-02-01 | $7700.00 | Window Closed / Lapsed |