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US5207705A Expired / Lapsed US ⏱️ 0.0 years remaining

Prosthesis of foam polyurethane and collagen and uses thereof

Assignee: The Brigham and Women's Hospital Inc
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Filing: 1989-12-08
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Granted: 1993-05-04
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Expires: 2009-12-08
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Abstract

Abstract An implantable medical prosthesis is provided having a uniform mixture of foam polyurethane and collagen. The prosthesis can be shaped into an elongated hollow body tube useful for implantation in an animal. Alternatively, the prosthesis can be shaped into biocompatible units useful as soft-tissue replacements or as matrices for sustained-release vehicles.

Inventors

  • 👤 Leonard A. Trudell
  • 👤 Anthony D. Whittemore

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 01:42
CPC Classifications
C; C08; C08L; C08L89/00; C08L89/04; C08L89/06; A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L; A61L27/00; A61L27/14; A61L27/26; A61L27/50; A61L27/56; A61F2/24; A61F2002/041; A61F2002/047; A61F2002/048; A61F2/28; A61F2002/2835; A61F2/30; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/30069; A61F2002/3007; A61F2002/30667; A61F2002/30677; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2310/00; A61F2310/00005; A61F2310/00365; Y; Y10; Y10S; Y10S521/00; Y10S521/905

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 49 words
A prosthesis useful for implantation in an animal, wherein said prosthesis comprises: at least one layer of a uniform mixture of closed-cell foam polyurethane and collagen in the shape of an elongated hollow body tube, said hollow body tube being open at both ends and defining a confined-flow passageway.
Claim 2
Dependent Claim 49 words
A prosthesis useful for implantation in an animal, wherein said prosthesis comprises: at least one layer of a uniform mixture of closed-cell foam polyurethane and collagen in the shape of an elongated hollow body tube, said hollow body tube being open at both ends and defining a confined-flow passageway.
Claim 3
Dependent Claim 23 words
The prosthesis of claim 1, wherein said prosthesis further comprises two or more layers of a uniform mixture of foam polyurethane and collagen.
Claim 4
Dependent Claim 18 words
The prosthesis of claim 1, wherein said prosthesis further comprises an outer layer which contains a silicone elastomer.
Claim 5
Dependent Claim 18 words
The prosthesis of claim 1, wherein the confined-flow passageway has an inner diameter of 10 mm or less.
Claim 6
Dependent Claim 18 words
The prosthesis of claim 1, wherein the confined-flow passageway has an inner diameter of 5 m or less.
Claim 7
Dependent Claim 14 words
The prosthesis of any one of claims 2-5, wherein said prosthesis contains an antibiotic.
Claim 8
Dependent Claim 14 words
The prosthesis of any one of claims 2-5, wherein said prosthesis contains a hormone.
Claim 9
Dependent Claim 15 words
The prosthesis of any one of claims 2-5, wherein said prosthesis contains an immunosuppressant agent.
Claim 10
Independent Claim 34 words
A method for implanting a vascular prosthesis which comprises suturing a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen into a blood vessel, tissue or other organ.
Claim 11
Independent Claim 34 words
A method for implanting a vascular prosthesis which comprises suturing a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen into a blood vessel, tissue or other organ.
Claim 12
Independent Claim 33 words
A method for implanting a ureteral prosthesis which comprises replacing the ureter, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Claim 13
Independent Claim 33 words
A method for implanting a ureteral prosthesis which comprises replacing the ureter, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Claim 14
Independent Claim 33 words
A method for implanting a urethral prosthesis which comprises replacing the urethra, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Claim 15
Independent Claim 33 words
A method for implanting a urethral prosthesis which comprises replacing the urethra, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Claim 16
Independent Claim 34 words
A method for implanting a biliary prosthesis which comprises replacing the bile duct, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Claim 17
Independent Claim 34 words
A method for implanting a biliary prosthesis which comprises replacing the bile duct, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Claim 18
Independent Claim 26 words
The method of any one of claims 9-12, wherein said prosthesis further comprises two or more layers of a uniform mixture of foam polyurethane and collagen.
Claim 19
Independent Claim 21 words
The method of any one of claims 9-12, wherein said prosthesis further comprises an outer layer which contains a silicone elastomer.
Claim 20
Independent Claim 16 words
The method of any one of claims 9-12, wherein said prosthesis further comprises closed-cell foam polyurethane.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-05-03 1996-11-02 1997-05-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-05-03 2000-11-02 2001-05-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-05-03 2004-11-02 2005-05-04 $7700.00 Window Closed / Lapsed

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