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Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients

Assignee: Cytogen Corp
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Filing: 1988-06-03
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Granted: 1992-11-10
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Expires: 2008-06-03
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Abstract

Abstract Monoclonal antibodies to prostatic cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies show specificity for a non-soluble, membrane associated, organ specific antigenic determinant limited in its distribution to normal and neoplastic, human prostate epithelial cells. The monoclonal antibodies, specifically 7E11-C5 monoclonal antibodies, may be suitable for diagnostic uses.

Inventors

  • 👤 Julius S. Horoszewicz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:38
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/18; C07K16/28; C07K16/30; C07K16/3069; A; A61; A61K; A61K38/00

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 48 words
A monoclonal antibody produced by hybridoma cell line 7E11-C5, ATCC Designation HB 10494, which monoclonal antibody binds specifically to an epitope present on a membrane associated antigen of human prostatic cancer epithelium and normal prostatic epithelium and which does not bind to non-prostatic antigens present in other tissues.
Claim 2
Dependent Claim 48 words
A monoclonal antibody produced by hybridoma cell line 7E11-C5, ATCC Designation HB 10494, which monoclonal antibody binds specifically to an epitope present on a membrane associated antigen of human prostatic cancer epithelium and normal prostatic epithelium and which does not bind to non-prostatic antigens present in other tissues.
Claim 3
Dependent Claim 8 words
Hybridoma cell line 7E11-C5, ATCC Designation HB 10494.
Claim 4
Dependent Claim 8 words
Hybridoma cell line 7E11-C5, ATCC Designation HB 10494.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-11-10 1996-05-11 1996-11-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-11-10 2000-05-11 2000-11-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-11-10 2004-05-11 2004-11-10 $7700.00 Window Closed / Lapsed

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