Patent US2247057A successfully refreshed from Google Patents.
US5152964A
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US
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Membrane blood oxygenator
Assignee: Terumo Cardiovascular Systems Corp
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Filing: 1991-02-15
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Granted: 1992-10-06
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Expires: 2011-02-15
Abstract
Abstract A membrane blood oxygenator having a mechanism for automatically maintaining the total pressure of the oxygenating gas near yet below that of the blood across the membrane is described. This includes a valve for restricting the flow of oxygenating gas exiting the oxygenator with the pressure of the blood exiting the oxygenator. A tubing communicates the pressure of the exiting blood to the valve to activate the valve.
Inventors
- 👤 Ronald J. Leonard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:41
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; A61M1/1621; A61M1/1623; A61M1/1625; A61M1/1629; A61M1/36; A61M1/3621; A61M1/3623; A61M39/00; A61M39/22; A61M39/227; A61M39/228; Y; Y10; Y10S; Y10S128/00; Y10S128/03; Y10S261/00; Y10S261/28
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
278 words
A membrane oxygenator comprising: a housing having means defining a hollow portion communicating with first and second inlet means and first and second outlet means, said first inlet means for providing an incoming flow of blood into the oxygenator, said first outlet means for providing an outgoing flow of blood from the oxygenator, said second inlet means for providing an incoming flow of oxygenating gas to the oxygenator and said second outlet means for providing an outgoing flow of oxygenating gas from the oxygenator; transfer membrane means comprising a hollow fiber bundle disposed within the hollow portion of the housing and defining oxygenating gas flow paths disposed between the first inlet means and the first outlet means and through individual fibers in said hollow fiber bundle, and defining blood flow paths disposed between the second inlet means and the second outlet means and around individual fibers in said hollow fiber bundle; and means for automatically maintaining the total pressure of the oxygenating gas at each point within the gas flow paths near yet below the total pressure of the blood on the other side of the transfer membrane means throughout the oxygenator, said automatic maintaining means being connected to said first and said second outlet means and comprising means for restricting the flow of oxygenating gas exiting the oxygenator through said first outlet means with the pressure of blood exiting the oxygenator through said second outlet means by providing a fluid with approximately the pressure of the blood exiting the oxygenator to exert pressure on the oxygenating gas exiting the oxygenator to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 2
Dependent Claim
278 words
A membrane oxygenator comprising: a housing having means defining a hollow portion communicating with first and second inlet means and first and second outlet means, said first inlet means for providing an incoming flow of blood into the oxygenator, said first outlet means for providing an outgoing flow of blood from the oxygenator, said second inlet means for providing an incoming flow of oxygenating gas to the oxygenator and said second outlet means for providing an outgoing flow of oxygenating gas from the oxygenator; transfer membrane means comprising a hollow fiber bundle disposed within the hollow portion of the housing and defining oxygenating gas flow paths disposed between the first inlet means and the first outlet means and through individual fibers in said hollow fiber bundle, and defining blood flow paths disposed between the second inlet means and the second outlet means and around individual fibers in said hollow fiber bundle; and means for automatically maintaining the total pressure of the oxygenating gas at each point within the gas flow paths near yet below the total pressure of the blood on the other side of the transfer membrane means throughout the oxygenator, said automatic maintaining means being connected to said first and said second outlet means and comprising means for restricting the flow of oxygenating gas exiting the oxygenator through said first outlet means with the pressure of blood exiting the oxygenator through said second outlet means by providing a fluid with approximately the pressure of the blood exiting the oxygenator to exert pressure on the oxygenating gas exiting the oxygenator to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 3
Dependent Claim
97 words
The membrane oxygenator according to claim 1 wherein the restricting means comprises: a valve member comprising an inner tube having an inlet and an outlet in fluid communication with the first outlet means of the housing of the oxygenator; a housing receiving the inner tube; an inlet portion connecting the housing to the inner tube adjacent the inlet of the inner tube; and an outlet portion connecting the housing to the inner tube adjacent the outlet of the inner tube; and means for maintaining an above-ambient pressure in the area between the housing and the inner tube.
Claim 4
Dependent Claim
26 words
The membrane oxygenator according to claim 2 wherein the inner tube comprises a relatively soft and flexible material that offers negligible resistance to externally applied forces.
Claim 5
Dependent Claim
32 words
The membrane oxygenator according to claim 3 wherein the maintaining means comprises a tubing communicating the pressure of the exiting blood to the area between the valve housing and the inner tube.
Claim 6
Dependent Claim
79 words
The membrane oxygenator according to claim 4 further comprising a portion of the valve housing having means defining an aperture therethrough and wherein the tubing has an inlet in fluid communication with the second outlet means of the housing oxygenator and the tubing has an outlet in fluid communication with the aperture through the valve housing to provide means whereby the pressure in the area between the valve housing and the inner tube approaches that of the exiting blood.
Claim 7
Dependent Claim
45 words
The membrane oxygenator according to claim 5 further comprising a fluid transducer between the inlet and the outlet of the tubing to provide means whereby a fluid other than the blood exiting the oxygenator pressurizes the area between the valve housing and the inner tube.
Claim 8
Dependent Claim
182 words
A membrane oxygenator comprising: a housing having inner surfaces defining a hollow portion, portions defining oxygenating gas inlet and outlet means for providing flow of oxygenating gas through the housing, and portions defining blood inlet and outlet means for providing flow of blood through the housing, transfer membrane means comprising a hollow fiber bundle disposed within the hollow portion of the housing for transfer of oxygen from oxygenating gas to the blood defining oxygenating gas flow paths through individual fibers in said hollow fiber bundle and defining blood flow paths around individual fibers in said hollow fiber bundle; and means, connected between said oxygenating gas outlet means and said blood outlet means, for restricting the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet means with the pressure of blood exiting the oxygenator through said blood outlet means by providing a fluid with approximately the pressure of the blood exiting the oxygenator to exert pressure on the oxygenating gas exiting the oxygenator to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 9
Dependent Claim
182 words
A membrane oxygenator comprising: a housing having inner surfaces defining a hollow portion, portions defining oxygenating gas inlet and outlet means for providing flow of oxygenating gas through the housing, and portions defining blood inlet and outlet means for providing flow of blood through the housing, transfer membrane means comprising a hollow fiber bundle disposed within the hollow portion of the housing for transfer of oxygen from oxygenating gas to the blood defining oxygenating gas flow paths through individual fibers in said hollow fiber bundle and defining blood flow paths around individual fibers in said hollow fiber bundle; and means, connected between said oxygenating gas outlet means and said blood outlet means, for restricting the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet means with the pressure of blood exiting the oxygenator through said blood outlet means by providing a fluid with approximately the pressure of the blood exiting the oxygenator to exert pressure on the oxygenating gas exiting the oxygenator to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 10
Dependent Claim
107 words
A membrane oxygenator according to claim 7, wherein said restricting means comprises a valve member including an inner tube having inner surface portions and an outer periphery, an inlet and an outlet in fluid communication with the oxygenating gas outlet means of the housing of the oxygenator; a valve housing receiving the inner tube, and means for communicating the pressure of the flow of blood exiting the oxygenator through said blood outlet means to the outer periphery of the inner tube so that the pressure of blood exiting the oxygenator may raise the pressure of the oxygenating bas within the oxygenator near that of the exiting blood.
Claim 11
Dependent Claim
220 words
A membrane oxygenator comprising: a housing having inner surfaces defining a hollow portion, portions defining oxygenating gas inlet and outlet means for providing flow of oxygenating gas through the housing, and portions defining blood inlet and outlet means for providing flow of blood through the housing, transfer membrane means comprising a hollow fiber bundle disposed within the hollow portion of the housing for transfer of oxygen from oxygenating gas to the blood defining oxygenating gas flow paths through individual fibers in said hollow fiber bundle and defining blood flow paths around individual fibers in said hollow fiber bundle; and a valve connected between said oxygenating gas outlet port and said blood outlet port, said valve including a tube for communicating the pressure of the flow of blood exiting the oxygenator through said blood outlet port to the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet port, said valve restricting the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet port with the pressure of blood exiting the oxygenator through said blood outlet port by providing fluid with approximately the pressure of the blood exiting the oxygenator to exert pressure on the oxygenating gas exiting the oxygenator to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 12
Dependent Claim
220 words
A membrane oxygenator comprising: a housing having inner surfaces defining a hollow portion, portions defining oxygenating gas inlet and outlet means for providing flow of oxygenating gas through the housing, and portions defining blood inlet and outlet means for providing flow of blood through the housing, transfer membrane means comprising a hollow fiber bundle disposed within the hollow portion of the housing for transfer of oxygen from oxygenating gas to the blood defining oxygenating gas flow paths through individual fibers in said hollow fiber bundle and defining blood flow paths around individual fibers in said hollow fiber bundle; and a valve connected between said oxygenating gas outlet port and said blood outlet port, said valve including a tube for communicating the pressure of the flow of blood exiting the oxygenator through said blood outlet port to the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet port, said valve restricting the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet port with the pressure of blood exiting the oxygenator through said blood outlet port by providing fluid with approximately the pressure of the blood exiting the oxygenator to exert pressure on the oxygenating gas exiting the oxygenator to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 13
Dependent Claim
15 words
A membrane oxygenator according to claim 9 wherein said valve includes an elastomeric inner tube.
Claim 14
Independent Claim
165 words
A method of oxygenating blood comprising: providing a membrane oxygenator comprising a housing having inner surfaces defining a hollow portion, transfer membrane means within the hollow portion, portions defining oxygenating gas inlet and outlet means, and portions defining blood inlet and outlet means, flowing oxygenating gas into the oxygenating gas inlet means, through the housing, and out through the oxygenating gas outlet means, flowing oxygen reduced blood into the blood inlet means, transferring oxygen from the oxygenating gas to the blood via the transfer membrane means within the housing and then flowing the blood out of the housing through the blood outlet means; providing pressure approximately the same as the pressure of the blood flowing through the blood outlet means on the flow of oxygenating gas exiting the oxygenating gas outlet means to restrict the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet means to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 15
Independent Claim
165 words
A method of oxygenating blood comprising: providing a membrane oxygenator comprising a housing having inner surfaces defining a hollow portion, transfer membrane means within the hollow portion, portions defining oxygenating gas inlet and outlet means, and portions defining blood inlet and outlet means, flowing oxygenating gas into the oxygenating gas inlet means, through the housing, and out through the oxygenating gas outlet means, flowing oxygen reduced blood into the blood inlet means, transferring oxygen from the oxygenating gas to the blood via the transfer membrane means within the housing and then flowing the blood out of the housing through the blood outlet means; providing pressure approximately the same as the pressure of the blood flowing through the blood outlet means on the flow of oxygenating gas exiting the oxygenating gas outlet means to restrict the flow of oxygenating gas exiting the oxygenator through said oxygenating gas outlet means to raise the pressure of the oxygenating gas within the oxygenator near that of the exiting blood.
Claim 16
Dependent Claim
81 words
A method according to claim 11 wherein the step of providing pressure approximately the same as the pressure of the blood flowing through the blood outlet means to the flow of oxygenating gas exiting the oxygenating gas outlet means comprises the step of: connecting a valve member between the oxygenating gas outlet means and the blood outlet means such that a change in blood pressure exiting the oxygenator changes the pressure of the oxygenating gas exiting the oxygenating gas outlet means.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-10-06 | 1996-04-06 | 1996-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-06 | 2000-04-06 | 2000-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-06 | 2004-04-06 | 2004-10-06 | $7700.00 | Window Closed / Lapsed |