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US5061281A Expired / Lapsed US ⏱️ 0.0 years remaining

Bioresorbable polymers and implantation devices thereof

Assignee: United States Surgical Corp
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Filing: 1986-12-17
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Granted: 1991-10-29
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Expires: 2006-12-17
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Abstract

Abstract This invention relates to an implantable medical device capable of encouraging cellular growth and regeneration of function fabricated totally or in part from one or more bioresorbable polymers, as for example bioresorbable homopolymers derived from the polymerization of alpha-hydroxy carboxylic acids, where at least one of the polymers has an average molecular weight of from about 234,000 to about 320,000 as measured by gel permeation chromatography.

Inventors

  • 👤 Frank Mares
  • 👤 Reginald T. Tang
  • 👤 Tin-Ho Chiu
  • 👤 Theodore Largman
  • 👤 Emery Nyilas, deceased

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 04:04
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/58; A61B; A61B17/00; A61B17/11; A61B17/1128; A61L27/14; A61L27/18; A61L27/28; A61L27/34; A61B2017/00004; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30224; A61F2002/30235; A61F2230/00; A61F2230/0063; A61F2230/0069; A61L2430/00; A61L2430/32

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 156 words
In an improved device suitable for implantation into a living organism said device capable of encouraging cellular growth and regeneration of function, the improvement which comprises all or a portion of said device comprised of a mixture of one or more bioresorbable polymers selected from the group consisting of a mixture of two or more bioresorbable homopolymers derived from the polymerization of alpha-hydroxy carboxylic acids, and a mixture of one or more bioresorbable terpolymers derived from the condensation of a dicarboxylic acid, an alpha hydroxy carboxylic acid and an aliphatic diol and one or more homopolymers derived from the polymerization of alpha-hydroxy carboxylic acids, said homopolymers and said terpolymers having an average molecular weight equal to or greater than about 150,000 as measured by gel permeation chromatography and wherein at least one of said homopolymers and said terpolymers has an average molecular weight of from about 234,000 to about 320,000 as measured by gel permeation chromatography.
Claim 2
Dependent Claim 156 words
In an improved device suitable for implantation into a living organism said device capable of encouraging cellular growth and regeneration of function, the improvement which comprises all or a portion of said device comprised of a mixture of one or more bioresorbable polymers selected from the group consisting of a mixture of two or more bioresorbable homopolymers derived from the polymerization of alpha-hydroxy carboxylic acids, and a mixture of one or more bioresorbable terpolymers derived from the condensation of a dicarboxylic acid, an alpha hydroxy carboxylic acid and an aliphatic diol and one or more homopolymers derived from the polymerization of alpha-hydroxy carboxylic acids, said homopolymers and said terpolymers having an average molecular weight equal to or greater than about 150,000 as measured by gel permeation chromatography and wherein at least one of said homopolymers and said terpolymers has an average molecular weight of from about 234,000 to about 320,000 as measured by gel permeation chromatography.
Claim 3
Dependent Claim 14 words
The device of claim 1 wherein at least one of said polymers is poly(lactide).
Claim 4
Dependent Claim 10 words
The device of claim 2 wherein said poly(lactide) is poly(DL-lactide).
Claim 5
Dependent Claim 23 words
The device of claim 3 wherein said mixture comprises two polymers one of which is poly(DL-lactide and the other of which is poly(l-lactide).
Claim 6
Dependent Claim 15 words
The device of claim 1 which is a nerve channel which comprises a tubular body.
Claim 7
Dependent Claim 24 words
The nerve channel of claim 5 wherein the mixture of bioresorbable polymers is in a form of a thin coating over a biodurable material.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1994-10-28 1995-04-29 1995-10-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1998-10-28 1999-04-29 1999-10-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2002-10-28 2003-04-29 2003-10-29 $7700.00 Window Closed / Lapsed

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