US4994298A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of making a biocompatible prosthesis
Assignee: Biogold Inc
•
Filing: 1990-04-18
•
Granted: 1991-02-19
•
Expires: 2010-04-18
Abstract
Abstract A method of making a biocompatible hollow artifact with perforated walls made from a substrate of electro-conductive material whose surface is exposed to a biological environment, such as living animal tissue or blood, to impart to said material biocompatibility at the site of exposure, comprising: subjecting said exposed surface of the substrate to exposure to a plasma gas discharge in a plasma zone containing a plasma polymerizable monomeric gas to form a thin flexible coating on said substrate, said exposure being performed for a sufficient period of time and under relative movement between said plasma zone and said substrate, the volume of said plasma zone being capable of complete immersion of the substrate and being of such a magnitude in relation to the volume of the substrate as to enable the substrate to travel in or through the plasma zone under plasma polymerization without disturbing the plasma generation.
Inventors
- 👤 Hirotsugu K. Yasuda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:09
CPC Classifications
B; B05; B05D; B05D1/00; B05D1/62; A; A61; A61L; A61L33/00; A61L33/0076; A61L33/0088; Y; Y10; Y10S; Y10S623/00; Y10S623/901
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
119 words
A method of making a biocompatible hollow artifact having perforated walls from a substrate of electro-conductive material which has a surface exposed to a biological environment including living animal tissue or blood, to impart to said material biocompatibility at the site of exposure, comprising: subjecting said exposed surface of the substrate of said electro-conductive material to exposure to a plasma gas discharge in a plasma zone containing a plasma polymerizable monomeric gas to form a thin flexible coating on said substrate, said exposure being performed for a predetermined period of time and during relative movement between said plasma zone and said substrate, said substrate traveling in and out of the plasma zone under plasma polymerization without disturbing plasma generation.
Claim 2
Independent Claim
119 words
A method of making a biocompatible hollow artifact having perforated walls from a substrate of electro-conductive material which has a surface exposed to a biological environment including living animal tissue or blood, to impart to said material biocompatibility at the site of exposure, comprising: subjecting said exposed surface of the substrate of said electro-conductive material to exposure to a plasma gas discharge in a plasma zone containing a plasma polymerizable monomeric gas to form a thin flexible coating on said substrate, said exposure being performed for a predetermined period of time and during relative movement between said plasma zone and said substrate, said substrate traveling in and out of the plasma zone under plasma polymerization without disturbing plasma generation.
Claim 3
Dependent Claim
26 words
A method according to claim 1, wherein the volume of said plasma zone is at least about ten (10) times larger than that of said substrate.
Claim 4
Dependent Claim
15 words
A method according to claim 1, wherein the substrate is moved in a circular path.
Claim 5
Dependent Claim
20 words
A method according to claim 1, where the substrate travels within said plasma zone for a predetermined period of time.
Claim 6
Dependent Claim
23 words
A method according to claim 1, wherein said substrate is subjected to both translational and rotational movement to ensure even deposition of polymer.
Claim 7
Dependent Claim
14 words
A method according to claim 1, wherein said substrate is an expandable tubular stent.
Claim 8
Dependent Claim
97 words
A method according to claim 6, wherein said stent is composed of a plurality of individual rigid but flexible and elastic thread elements each of which extends in helix configuration along and around the centerline of said stent as a common axis, said stent being provided with a first number of thread elements having a common direction of winding and being axially displaced relative to each other, and with a second number of thread elements also axially displaced relative to each other but having an opposite direction of winding thus crossing said first number of thread elements.
Claim 9
Dependent Claim
25 words
A method according to claim 7, wherein the crossing thread elements are arranged in a braid-like configuration so as to impart stability to the stent.
Claim 10
Dependent Claim
33 words
A method according to claim 1, wherein said monomeric gas contains monomers selected from hydrocarbons and halogenated hydrocarbons, optionally together with hydrogen, to deposit onto the substrate a thin and flexible carbonaceous layer.
Claim 11
Dependent Claim
22 words
A method according to claim 9, wherein said monomers are selected from fluorinated hydrocarbons and hydrocarbons having 1 to 6 carbon atoms.
Claim 12
Dependent Claim
12 words
A method according to claim 10, wherein said monomeric gas contains tetrafluoroethylene.
Claim 13
Dependent Claim
20 words
A method according to claim 2, where the substrate travels within said plasma zone for a predetermined period of time.
Claim 14
Dependent Claim
23 words
A method according to claim 3, wherein said substrate is subjected to both translational and rotational movement to ensure even deposition of polymer.
Claim 15
Dependent Claim
23 words
A method according to claim 4, wherein said substrate is subjected to both translational and rotational movement to ensure even deposition of polymer.
Claim 16
Dependent Claim
23 words
A method according to claim 12, wherein said substrate is subjected to both translational and rotational movement to ensure even deposition of polymer.
Claim 17
Dependent Claim
33 words
A method according to claim 7, wherein said monomeric gas contains monomers selected from hydrocarbons and halogenated hydrocarbons, optionally together with hydrogen, to deposit onto the substrate a thin and flexible carbonaceous layer.
References Cited (Backward Citations)
US3839743A
Cited
US4164794A
Cited
US4188426A
Cited
JPS5712032A
Cited
US4444805A
Cited
US4655771B1
Cited
US4655771A
Cited
JPS58208326A
Cited
US4656083A
Cited
US4673588A
Cited
US4690097A
Cited
US4636435A
Cited
US4718907A
Cited
US4776337A
Cited
US4776337B1
Cited
GB2189150A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-02-18 | 1994-08-20 | 1995-02-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-02-18 | 1998-08-20 | 1999-02-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-02-18 | 2002-08-20 | 2003-02-19 | $7700.00 | Window Closed / Lapsed |