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US4981483A
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US
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Biocompatible material for treatment of tissular or organic defects
Assignee: Moskovsky Nauchno-Issledovatelsky Onkologichesky Institut Imeni Pa Gertsena
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Filing: 1987-01-14
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Granted: 1991-01-01
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Expires: 2007-01-14
Abstract
Abstract A biocompatible material for treatment of tissular or organic defects is composed of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular weight of 200,000 to 600,000, obtained by interaction of alpha-cyanacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows: ______________________________________ alpha-cyanacrylate 14 to 34 polyacrylic acid having a molecular weight of 200,000 to 600,000 15 to 43 cross-linking agent 71 to 23 ______________________________________ .
Inventors
- 👤 Alla Y. Akimova
- 👤 Anatoly B. Davydov
- 👤 Valery N. Egiev
- 👤 Anna I. Iliina
- 👤 Jury P. Kapustin
- 👤 Anesty K. Orfanidi
- 👤 Alexei N. Smirnov
- 👤 Eduard A. Stepanov
- 👤 Valeria I. Timokhina
- 👤 Anatoly Nikolaevich Chigir
- 👤 Kirill G. Schitkov
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:21
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/04; A61L24/06; A61L26/00; A61L26/0009; A61L26/0014; A61P; A61P17/00; A61P43/00; Y; Y10; Y10S; Y10S623/00; Y10S623/92
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
92 words
A biocompatible material for treatment of tissular or organic defects in a patient, said material comprised of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular weight of 200,000 to 600,000, obtained by interaction of alpha-cyanoacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows: ______________________________________
alpha-cyanoacrylate 14 to 34
polyacrylic acid having a molecular weight
of 200,000 to 600,000 15 to 43
cross-linking agent 71 to 23
______________________________________ and wherein said material is resorbable by said patient.
Claim 2
Dependent Claim
92 words
A biocompatible material for treatment of tissular or organic defects in a patient, said material comprised of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular weight of 200,000 to 600,000, obtained by interaction of alpha-cyanoacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows: ______________________________________
alpha-cyanoacrylate 14 to 34
polyacrylic acid having a molecular weight
of 200,000 to 600,000 15 to 43
cross-linking agent 71 to 23
______________________________________ and wherein said material is resorbable by said patient.
Claim 3
Dependent Claim
19 words
A biocompatible material as claimed in claim 1, which comprises, as said alpha-cyanoacrylate, ethyl-alpha-cyanoacrylate, ethoxyethyl-alpha-cyanoacrylate, butyl-alpha-cyanoacrylate, or mixtures thereof.
Claim 4
Dependent Claim
31 words
A biocompatible material as claimed in claims 1 or 2, wherein said cross-linking agent is polyvinyl alcohol having a molecular weight of 500,000 to 600,000, glycerol or a mixture of both.
Claim 5
Dependent Claim
24 words
A biocompatible material as claimed in claims 1 or 2, which comprises additionally an antiseptic in an amount of 9 to 50 weight percent.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-12-31 | 1994-07-02 | 1995-01-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-12-31 | 1998-07-02 | 1999-01-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-12-31 | 2002-07-02 | 2003-01-01 | $7700.00 | Window Closed / Lapsed |