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US4950699A Expired / Lapsed US ⏱️ 0.0 years remaining

Wound dressing incorporating collagen in adhesive layer

Assignee: Genetic Laboratories Wound Care Inc
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Filing: 1989-05-11
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Granted: 1990-08-21
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Expires: 2009-05-11
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Abstract

Abstract A composition and formulation for use in covering and healing of wounds to the body, the formulation consisting of a mixture of a tissue compatible, water-based acrylic adhesive and collagen. The formulation comprises from between about 0.1% and 10% of collagen (dry basis), with the adhesive component preferably containing about 50% solids, balance water.

Inventors

  • 👤 Daniel G. Holman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 10:16
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/58; A61L15/585; A61L26/00; A61L26/0009; A61L26/0028; A61L26/0033; A61L26/0052

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 118 words
A wound dressing composition to be applied to a wound to reduce bleeding and aid healing consisting substantially of: an amount of bodily tissue compatible, water based acrylic adhesive material consisting of a blend of copolymers of N-butyl acrylate and acrylamide and a copolymer of N-butyl acrylate and methyl methacrylate adapted to removably adhere to the tissue surface of the body adjacent a wound; an amount of collagen in homogeneous admixture with said formulation in an amount ranging between about 0.1% and 10% by weight of collagen on a dry basis in said adhesive; and wherein said adhesive establishes and maintains contact between the collagen and the tissue at said wound site when the admixture is applied thereto.
Claim 2
Dependent Claim 118 words
A wound dressing composition to be applied to a wound to reduce bleeding and aid healing consisting substantially of: an amount of bodily tissue compatible, water based acrylic adhesive material consisting of a blend of copolymers of N-butyl acrylate and acrylamide and a copolymer of N-butyl acrylate and methyl methacrylate adapted to removably adhere to the tissue surface of the body adjacent a wound; an amount of collagen in homogeneous admixture with said formulation in an amount ranging between about 0.1% and 10% by weight of collagen on a dry basis in said adhesive; and wherein said adhesive establishes and maintains contact between the collagen and the tissue at said wound site when the admixture is applied thereto.
Claim 3
Dependent Claim 23 words
The composition of claim 1 particularly characterized in that said collagen is added in the form of a water insoluble hydrochloric acid salt.
Claim 4
Dependent Claim 36 words
The composition of claim 1 particularly characterized in that said water based acrylic adhesive is incorporated in the composition in the form of a gel containing approximately 50% acrylic adhesive solids, and the balance is water.
Claim 5
Dependent Claim 36 words
The composition of claim 2 particularly characterized in that said water based acrylic adhesive is incorporated in the composition in the form of a gel containing approximately 50% acrylic adhesive solids, and the balance is water.
Claim 6
Dependent Claim 14 words
The composition of claim 2 particularly characterized in that said collagen is bovine collagen.
Claim 7
Dependent Claim 213 words
A covering for aiding healing of a wound of interest in a tissue surface of the body which consisting substantially of: a backing material, said backing material being at least large enough to cover the wound of interest and overlap a portion of the tissue surface adjacent thereto and in the form of a microscopically fibrous and porous film; and a wound dressing composition for adhering said backing to the tissue surface of the body and to be applied directly to the wound to reduce bleeding and aid healing, said dressing composition further comprising; an amount of body tissue compatible water based acrylic adhesive material consisting of a blend of copolymers of N-butyl acrylate and acrylamide and a copolymer of N-butyl acrylate and methyl methacrylate on said backing adapted to adhere to said backing material and removably adhere to the tissue surface of the body adjacent a wound; and an amount of collagen in homogeneous admixture with said adhesive wherein said collagen is contained in said formulation in an amount ranging between 0.1% and 10% by weight of collagen on a dry basis in said adhesive; and wherein said adhesive establishes and maintains contact between said collagen and the tissue at said wound site upon application of said covering to said tissue surface.
Claim 8
Dependent Claim 213 words
A covering for aiding healing of a wound of interest in a tissue surface of the body which consisting substantially of: a backing material, said backing material being at least large enough to cover the wound of interest and overlap a portion of the tissue surface adjacent thereto and in the form of a microscopically fibrous and porous film; and a wound dressing composition for adhering said backing to the tissue surface of the body and to be applied directly to the wound to reduce bleeding and aid healing, said dressing composition further comprising; an amount of body tissue compatible water based acrylic adhesive material consisting of a blend of copolymers of N-butyl acrylate and acrylamide and a copolymer of N-butyl acrylate and methyl methacrylate on said backing adapted to adhere to said backing material and removably adhere to the tissue surface of the body adjacent a wound; and an amount of collagen in homogeneous admixture with said adhesive wherein said collagen is contained in said formulation in an amount ranging between 0.1% and 10% by weight of collagen on a dry basis in said adhesive; and wherein said adhesive establishes and maintains contact between said collagen and the tissue at said wound site upon application of said covering to said tissue surface.
Claim 9
Dependent Claim 23 words
The covering of claim 6 particularly characterized in that said collagen is added in the form of a water insoluble hydrochloric acid salt.
Claim 10
Dependent Claim 34 words
The covering of claim 5 particularly characterized in that said water based acrylic adhesive is incorporated in the composition in the form of a gel containing approximately 50% acrylic adhesive solids, the balance water.
Claim 11
Dependent Claim 23 words
The covering of claim 8 particularly characterized in that said collagen is added in the form of a water insoluble hydrochloric acid salt.
Claim 12
Dependent Claim 31 words
The covering as defined in claim 6 being particularly characterized in that said microscopically fibrous, porous film is semitransparent and consists essentially of a loosely woven sheet of water stabilized collagen.
Claim 13
Dependent Claim 29 words
The covering as defined in claim 6 being particularly characterized in that said microscopically fibrous, porous film is semitransparent and consists essentially of a combination of polyurethane fibrous collagen.

References Cited (Backward Citations)

US4746514A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-08-20 1994-02-19 1994-08-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-08-20 1998-02-19 1998-08-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-08-20 2002-02-19 2002-08-21 $7700.00 Window Closed / Lapsed

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