US4931053A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for enhanced vascular or other growth
Assignee: L'ESPERANCE MEDICAL TECHNOLOGIES Inc
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Filing: 1988-01-27
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Granted: 1990-06-05
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Expires: 2008-01-27
Abstract
Abstract The invention comtemplates promotion or enhanced promotion of vascular or other growth in living body tissue through effectively concurrent in-vivo delivery of at least two beams of laser irradiation at an affected area of body tissue, wherein the irradiation (a) is of low intensity at tissue impingement and (b) is also of spectral wavelength that is preferably in the visible red or in the infrared. Perturbations result in affected cells either directly by reason of differences in the physical properties of the respective beams or indirectly by reason of interaction between the two beams at or near the situs of delivery to the affected body tissue.
Inventors
- 👤 Francis A. L'Esperance, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:04
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0601; A61F; A61F9/00; A61F9/007; A61F9/008; A61N5/0613; A61N5/062; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/203; A61B2018/00315; A61B2018/00452; A61B2018/00476; A61F2009/00861; A61F2009/00863; A61F9/009; A61N2005/0635; A61N2005/0643; A61N2005/0644; A61N5/067
Claims Analysis
Total Claims: 65
Claim 1
Independent Claim
129 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of beam delivery to said area being in the range up to 150 microwatts/cm 2 and at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 2
Dependent Claim
129 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of beam delivery to said area being in the range up to 150 microwatts/cm 2 and at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 3
Dependent Claim
120 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a polarization shift of one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 4
Dependent Claim
120 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a polarization shift of one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 5
Dependent Claim
120 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining an intensity difference at one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 6
Dependent Claim
120 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining an intensity difference at one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 7
Dependent Claim
112 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means including a chopper operative upon at least one of said beams prior to incidence with said beam splitter, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 8
Dependent Claim
112 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means including a chopper operative upon at least one of said beams prior to incidence with said beam splitter, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 9
Dependent Claim
112 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beam of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means including synchronized first and second choppers operative upon said respective beams prior to incidence with said beam splitter, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 10
Dependent Claim
112 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beam of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means including synchronized first and second choppers operative upon said respective beams prior to incidence with said beam splitter, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 11
Dependent Claim
112 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a first laser producing a first output beam at a first wavelength, a second laser producing a second output beam at a second wavelength, and means including a rotatable chopper having a mirror surface for combining said beams for coordinated interlace of their delivery to and interaction with tissue at said area, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 12
Dependent Claim
112 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a first laser producing a first output beam at a first wavelength, a second laser producing a second output beam at a second wavelength, and means including a rotatable chopper having a mirror surface for combining said beams for coordinated interlace of their delivery to and interaction with tissue at said area, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 13
Dependent Claim
31 words
Apparatus according to any one of claims 2, 3, 4, or 5 the intensity of beam energy deliverable to said area is in the range up to 150 microwatts/cm 2 .
Claim 14
Dependent Claim
22 words
Apparatus according to any one of claims 2, 3, 4, 5 or 6 in which said wavelength is at least 600 nanometers.
Claim 15
Dependent Claim
45 words
Apparatus according to any one of claims 2, 3, 4 or 5, in which said laser means comprises a laser producing a single output, and means including a beam splitter exposed to said output for dividing the same into said first and second output beams.
Claim 16
Dependent Claim
55 words
Apparatus according to any one of claims 2, 3, 4, or 5, in which said laser means comprises a laser producing a single output, and means including a beam splitter exposed to said output for dividing the same into said first and second output beams, and in which said laser means is a helium-neon laser.
Claim 17
Dependent Claim
55 words
Apparatus according to any one of claims 2, 3, 4, or 5, in which said laser means comprises a laser producing a single output, and means including a beam splitter exposed to said output for dividing the same into said first and second output beams, and in which said laser means is a krypton laser.
Claim 18
Dependent Claim
55 words
Apparatus according to any one of claims 2, 3, 4, or 5, in which said laser means comprises a laser producing a single output, and means including a beam splitter exposed to said output for dividing the same into said first and second output beams, and in which said laser means is a diode laser.
Claim 19
Dependent Claim
32 words
Apparatus, according to any one of claims 2, 3, 4, 5, or 6, in which delivery of the energy of at least one of said beams is with spatial and temporal coherence.
Claim 20
Dependent Claim
30 words
Apparatus according to any one of claims 2, 3, 4, 5, or 6, in which delivery of the energy of each of said beams is with spatial and temporal coherence.
Claim 21
Dependent Claim
37 words
Apparatus according to any of claims 2, 3, 4, 5, or 6, in which delivery of the energy of the respective beams is on separate alignments which are convergent for substantial intersecting overlap at said local area.
Claim 22
Dependent Claim
26 words
Apparatus according to claim 2 or claim 3 in which said means operable upon one with respect to the other of said beams is selectively variable.
Claim 23
Dependent Claim
12 words
Apparatus according to claim 5 in which said choppers are electro-optical choppers.
Claim 24
Dependent Claim
17 words
Apparatus according to claim 5, in which said choppers are operative upon said beams in phase-interlaced relation.
Claim 25
Dependent Claim
17 words
Apparatus according to claim 5, in which said choppers are operative upon said beams in phase coincidence.
Claim 26
Dependent Claim
22 words
Apparatus according to claim 5, in which said choppers are operative upon said beams in phase-offset but at least partially overlapping relation.
Claim 27
Dependent Claim
94 words
Apparatus according to any one of claims 2, 3, 4, 5, or 6, in which the intensity of beam energy deliverable to said area is in the range of 100 to 150 microwatts/cm 2 and the wavelength of each of said beams is at least 600 nanometers, and in which, in addition to said beam splitter, said means for coordinated delivery includes a dichroic mirror which is of reflectance conforming substantially to beam-wavelength limitation, thereby establishing an axis of viewing said area through said dichroic mirror, and a viewing optical system on said axis.
Claim 28
Dependent Claim
35 words
Apparatus according to any one of claims 2, 3, 4, 5, or 6, in which the intensity of beam energy deliverable to said area is in the range of 100 to 150 microwatts/cm 2 .
Claim 29
Dependent Claim
16 words
Apparatus according to claim 6, in which each of said wavelength is at least 600 nanometers.
Claim 30
Dependent Claim
35 words
Apparatus according to any one of claims 2, 3, 4, 5, or 6, in which the range of intensity of beam energy deliverable to said area includes the range 100 to 150 microwatts/cm 2 .
Claim 31
Dependent Claim
22 words
Apparatus according to any one of claims 4, 5, or claim 6, in which the chopping rate exceeds substantially 15 per second.
Claim 32
Dependent Claim
24 words
Apparatus according to any one of claims 4, 5, or claim 6, in which the chopping rate is less than substantially 15 per second.
Claim 33
Dependent Claim
115 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a first laser producing a first output beam at a first wavelength, a second laser producing a second output beam at a second wavelength, and means including a beam splitter for combining said beams for coordinate delivery to and interaction with tissue at said local area, the combined intensity of beam delivery to said area being in the range up to 150 microwatts/cm 2 and at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 34
Dependent Claim
115 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a first laser producing a first output beam at a first wavelength, a second laser producing a second output beam at a second wavelength, and means including a beam splitter for combining said beams for coordinate delivery to and interaction with tissue at said local area, the combined intensity of beam delivery to said area being in the range up to 150 microwatts/cm 2 and at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 35
Dependent Claim
17 words
Apparatus according to claim 27, in which at least one of said lasers is a diode laser.
Claim 36
Dependent Claim
16 words
Apparatus according to claim 27, in which each of said wavelengths is at least 600 nanometers.
Claim 37
Dependent Claim
108 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for generating two low-power beams of laser radiation, and laser beam delivery means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams differing physically in at least one respect and having a combined intensity which is in the range up to 150 microwatts/cm 2 and at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 38
Dependent Claim
108 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for generating two low-power beams of laser radiation, and laser beam delivery means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams differing physically in at least one respect and having a combined intensity which is in the range up to 150 microwatts/cm 2 and at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 39
Dependent Claim
13 words
Apparatus according to claim 30, in which said beams are of different wavelength.
Claim 40
Dependent Claim
150 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, said laser means comprising a laser producing a single output, and means including beam-splitter means exposed to said output for dividing the same into said first and second output beams; means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area; and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 41
Dependent Claim
150 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, said laser means comprising a laser producing a single output, and means including beam-splitter means exposed to said output for dividing the same into said first and second output beams; means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area; and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 42
Dependent Claim
122 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising helium-neon laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of said beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 43
Dependent Claim
122 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising helium-neon laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of said beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 44
Dependent Claim
121 words
Apparatus for enchancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising krypton laser means producing first and second output beams of identical wavelength, means including beam-splitter means for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of said beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 45
Dependent Claim
121 words
Apparatus for enchancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising krypton laser means producing first and second output beams of identical wavelength, means including beam-splitter means for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the combined intensity of said beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 46
Dependent Claim
106 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a helium-neon laser producing a first output beam at a first wavelength, a krypton laser producing a second output beam at a second wavelength, and means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 47
Dependent Claim
106 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a helium-neon laser producing a first output beam at a first wavelength, a krypton laser producing a second output beam at a second wavelength, and means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 48
Dependent Claim
145 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the delivery of the energy of the respective beams being on separate alignments which are convergent for substantial intersecting overlap at said local area, and the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 49
Dependent Claim
145 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, and means operable upon one with respect to the other of said beams for determining a phase shift of one with respect to the other of said beams, the delivery of the energy of the respective beams being on separate alignments which are convergent for substantial intersecting overlap at said local area, and the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 50
Dependent Claim
130 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a first laser producing a first output beam at a first wavelength, a second laser producing a second output beam at a second wavelength, and means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, the delivery of the energy of the respective beams being on separate alignments which are convergent for substantial intersecting overlap at said local area, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 51
Dependent Claim
130 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising a first laser producing a first output beam at a first wavelength, a second laser producing a second output beam at a second wavelength, and means including a beam splitter for combining said beams for coordinated delivery to and interaction with tissue at said local area, the delivery of the energy of the respective beams being on separate alignments which are convergent for substantial intersecting overlap at said local area, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 52
Dependent Claim
97 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams being of the same wavelength and being directed to impact said area from different convergent aspects, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient ti induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 53
Dependent Claim
97 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams being of the same wavelength and being directed to impact said area from different convergent aspects, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient ti induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 54
Dependent Claim
83 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams being of the same wavelength but in phase-offset relation to each other, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 55
Dependent Claim
83 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams being of the same wavelength but in phase-offset relation to each other, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 56
Dependent Claim
87 words
Apparatus for enchancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams being polarized in mutually offset planes, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 57
Dependent Claim
87 words
Apparatus for enchancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams being polarized in mutually offset planes, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 58
Dependent Claim
114 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, one of said beams being directed to impact body tissue over an area greater than but fully overlapping the area of impact by the other of said beams, said beams differing physically in at least one respect and having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 59
Dependent Claim
114 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, one of said beams being directed to impact body tissue over an area greater than but fully overlapping the area of impact by the other of said beams, said beams differing physically in at least one respect and having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 60
Dependent Claim
89 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beam of laser radiation to a single local area of impact and interaction with body tissue, said beams being of different wavelength and in chopped interlace, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 61
Dependent Claim
89 words
Apparatus for enhancing or promoting vascular or other tissue growth in a living body, said apparatus comprising laser means for delivering two low-power beam of laser radiation to a single local area of impact and interaction with body tissue, said beams being of different wavelength and in chopped interlace, and said beams having a combined intensity which is at least sufficient to therapeutically affect beam-impacted body tissue and/or cells and which is less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 62
Dependent Claim
121 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to an interaction with tissue at said local area, and selectively variable means operable upon one with respect to the other of said beams for determining a phase of one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 63
Dependent Claim
121 words
Apparatus for enhancement of vascular or other tissue growth by laser irradiation of a local area of living body tissue, comprising laser means producing first and second output beams of identical wavelength, means including a beam splitter for combining said beams for coordinated delivery to an interaction with tissue at said local area, and selectively variable means operable upon one with respect to the other of said beams for determining a phase of one with respect to the other of said beams, the combined intensity of beam delivery to said area being at least sufficient to therapeutically affect beam-impacted body tissue and/or cells but less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 64
Independent Claim
96 words
The method of enhancing or promoting vascular or other tissue growth in a living body, which method comprises delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams differing physically in at least one respect, and adjusting said beams for a combined intensity which is (a) in the range up to 150 microwatts/cm 2 , (b) at least sufficient to therapeutically affect beam-impacted tissue and/or cells and (c) less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
Claim 65
Independent Claim
96 words
The method of enhancing or promoting vascular or other tissue growth in a living body, which method comprises delivering two low-power beams of laser radiation to a single local area of impact and interaction with body tissue, said beams differing physically in at least one respect, and adjusting said beams for a combined intensity which is (a) in the range up to 150 microwatts/cm 2 , (b) at least sufficient to therapeutically affect beam-impacted tissue and/or cells and (c) less than sufficient to induce photocoagulation, photovaporization, photonoptical-tissue breakdown, or photoablative decomposition of living tissue and/or cells.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-06-04 | 1993-12-04 | 1994-06-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-06-04 | 1997-12-04 | 1998-06-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-06-04 | 2001-12-04 | 2002-06-05 | $7700.00 | Window Closed / Lapsed |