US4902511A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fibrous and cartilaginous tissue replacement
Assignee: Individual
•
Filing: 1989-07-24
•
Granted: 1990-02-20
•
Expires: 2009-07-24
Abstract
Abstract Disclosed is new type of implantable material for replacement of cartilaginous or fibrous tissue. The material has controlled porosity and is biocompatible. A method for making this material is also disclosed.
Inventors
- 👤 Joseph H. Kronman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:50
CPC Classifications
C; C08; C08J; C08J9/00; C08J9/26; A; A61; A61L; A61L27/00; A61L27/14; A61L27/16; A61L27/50; A61L27/56; A61M; A61M25/00; A61M25/01; A61M25/09; A61M2025/09058; A61M2025/09066; A61M2025/09191; Y; Y10; Y10S; Y10S521/00; Y10S521/905; Y10S521/915; Y10S521/918
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
163 words
A biocompatible implant for replacement of fibrous connective tissue comprising a hydrophilic polymeric material having pores of a single controlled pore size randomly distributed throughout the body of said implant, substantially all of said pores comprising a single pore size in a selected range of about 300 to about 450μ in diameter, said pores being formed in said polymeric material by: A. dispersing water-dissolvable salt crystals of a size corresponding to said single pore size of about 300 to 450μ in diameter in an unpolymerized monomer of a hydrophilic polymerizable material; B. polymerizing said monomer with said salt crystals dispersed therein to form a polymeric material with said salt crystals randomly dispersed throughout substantially all of said implant; C. subjecting said polymeric material with salt crystals dispersed therein to an aqueous solution whereby said salt crystals are dissolved, and form said pores in said polymerical material at locations previously occupied by said salt crystals; and D. shaping said polymeric material into said implant.
Claim 2
Dependent Claim
163 words
A biocompatible implant for replacement of fibrous connective tissue comprising a hydrophilic polymeric material having pores of a single controlled pore size randomly distributed throughout the body of said implant, substantially all of said pores comprising a single pore size in a selected range of about 300 to about 450μ in diameter, said pores being formed in said polymeric material by: A. dispersing water-dissolvable salt crystals of a size corresponding to said single pore size of about 300 to 450μ in diameter in an unpolymerized monomer of a hydrophilic polymerizable material; B. polymerizing said monomer with said salt crystals dispersed therein to form a polymeric material with said salt crystals randomly dispersed throughout substantially all of said implant; C. subjecting said polymeric material with salt crystals dispersed therein to an aqueous solution whereby said salt crystals are dissolved, and form said pores in said polymerical material at locations previously occupied by said salt crystals; and D. shaping said polymeric material into said implant.
Claim 3
Dependent Claim
23 words
The fibrous implant of claim 1 wherein said monomer is selected from a group consisting of monomers of hydrophilic acrylates and hydrophilic methacrylates.
Claim 4
Dependent Claim
12 words
The implant of claim 2 wherein said hydrophilic acrylates comprise hydroxyalkyl acrylates.
Claim 5
Dependent Claim
12 words
The implant of claim 2 wherein said hydrophilic methacrylates comprise hydroxyalkyl methacrylates.
Claim 6
Dependent Claim
12 words
The implant of claim 4 wherein said hydroxyalkyl methacrylates comprise hydroxyethyl methacrylate.
Claim 7
Dependent Claim
18 words
The implant of claim 5 wherein said hydrophilic polymeric material consists essentially of a homopolymer of hydroxyethyl methacrylate.
Claim 8
Dependent Claim
23 words
The implant of claim 1 wherein said salt crystals are selected from a group consisting of sodium chloride, potassium chloride, and calcium chloride.
Claim 9
Dependent Claim
20 words
The implant of claim 1 wherein said hydrophilic polymeric material comprises polyhydroxyethyl methacrylate and said salt crystals comprise sodium chloride.
Claim 10
Dependent Claim
13 words
The implant of claim 1 wherein said implant comprises a human breast implant.
Claim 11
Dependent Claim
13 words
The implant of claim 1 wherein said implant comprises a human nasal implant.
Claim 12
Dependent Claim
161 words
A biocompatible implant for replacement of cartilaginous tissue comprising a hydrophilic polymeric material having pores of a single controlled size randomly distributed throughout the body of said implant, substantially all of said pores comprising a single pore size in a selected range of about 225 to about 275μ in diameter, said pores being formed in said polymeric material by: A. dispersing water-dissolvable salt crystals of a size corresponding to said single pore size of about 225 to about 275μ in diameter in an unpolymerized monomer of a hydrophilic polymerizable material; B. polymerizing said monomer with said salt crystals dispersed therein to form a polymeric material with salt crystals randomly dispersed through substantially all of said implant; C. subjecting said polymeric material with salt crystals dispersed therein to an aqueous solution whereby said salt crystals are dissolved, and form said pores in said polymeric material at locations previously occupied by said salt crystals; and D. shaping said polymeric material into said implant.
Claim 13
Dependent Claim
161 words
A biocompatible implant for replacement of cartilaginous tissue comprising a hydrophilic polymeric material having pores of a single controlled size randomly distributed throughout the body of said implant, substantially all of said pores comprising a single pore size in a selected range of about 225 to about 275μ in diameter, said pores being formed in said polymeric material by: A. dispersing water-dissolvable salt crystals of a size corresponding to said single pore size of about 225 to about 275μ in diameter in an unpolymerized monomer of a hydrophilic polymerizable material; B. polymerizing said monomer with said salt crystals dispersed therein to form a polymeric material with salt crystals randomly dispersed through substantially all of said implant; C. subjecting said polymeric material with salt crystals dispersed therein to an aqueous solution whereby said salt crystals are dissolved, and form said pores in said polymeric material at locations previously occupied by said salt crystals; and D. shaping said polymeric material into said implant.
Claim 14
Dependent Claim
23 words
The cartilaginous implant of claim 11 wherein said monomer is selected from a group consisting of monomers of hydrophilic acrylates and hydrophilic methacrylates.
Claim 15
Dependent Claim
12 words
The implant of claim 12 wherein said hydrophilic acrylates comprise hydroxyalkyl acrylates.
Claim 16
Dependent Claim
12 words
The implant of claim 12 wherein said hydrophilic methacrylates comprise hydroxyalkyl methacrylates.
Claim 17
Dependent Claim
12 words
The implant of claim 14 wherein said hydroxyalkyl methacrylates comprise hydroxyethyl methacrylate.
Claim 18
Dependent Claim
17 words
The implant of claim 15 wherein said polymeric material consists essentially of a homopolymer of hydroxyethyl methacrylate.
Claim 19
Dependent Claim
23 words
The implant of claim 11 wherein said salt crystals are selected from a group consisting of sodium chloride, potassium chloride, and calcium chloride.
Claim 20
Dependent Claim
20 words
The implant of claim 11 wherein said hydrophilic polymeric material comprises polyhydroxyethyl methacrylate and said salt crystals comprise sodium chloride.
Claim 21
Dependent Claim
13 words
The implant of claim 11 wherein said implant comprises a human nasal implant.
Claim 22
Dependent Claim
13 words
The implant of claim 11 wherein said implant comprises a human ear implant.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-02-19 | 1993-08-21 | 1994-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-02-19 | 1997-08-21 | 1998-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-02-19 | 2001-08-21 | 2002-02-20 | $7700.00 | Window Closed / Lapsed |