US4900546A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bone cement for sustained release of substances
Assignee: Howmedica Osteonics Corp
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Filing: 1987-07-30
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Granted: 1990-02-13
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Expires: 2007-07-30
Abstract
Abstract A bone cement is disclosed wherein the liquid component contains a therapeutic or diagnostic substance in combination with an emulsifying agent for said substance.
Inventors
- 👤 Jessica D. Posey-Dowty
- 👤 Paul A. Higham
- 👤 Nestor Arroyo
- 👤 Casper F. Stark
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:05
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/001; A61L24/0015; A61L24/04; A61L24/06; A61L2300/00; A61L2300/40; A61L2300/404; A61L2300/406; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
69 words
A bone cement composition comprising the combination of components A and B wherein: Component A comprises a powdered polymer or copolymer of an acrylic ester and, component B comprises a liquid monomer of an acrylic ester containing (a) erythromycin or pharmaceutically acceptable salts thereof, an emulsifying agent for erythromycin, or pharmaceutically acceptable salts thereof, whereby the incorporation of erythromycin, or pharmaceutically acceptable salts thereof, is substantially in component B.
Claim 2
Dependent Claim
69 words
A bone cement composition comprising the combination of components A and B wherein: Component A comprises a powdered polymer or copolymer of an acrylic ester and, component B comprises a liquid monomer of an acrylic ester containing (a) erythromycin or pharmaceutically acceptable salts thereof, an emulsifying agent for erythromycin, or pharmaceutically acceptable salts thereof, whereby the incorporation of erythromycin, or pharmaceutically acceptable salts thereof, is substantially in component B.
Claim 3
Dependent Claim
12 words
The bone cement of claim 1 wherein component A is polymethyl methacrylate.
Claim 4
Dependent Claim
16 words
The bone cement of claim 1 wherein component A is a copolymer of methylmethacrylate and styrene.
Claim 5
Dependent Claim
11 words
The bone cement of claim 1 wherein component B is methylmethacrylate.
Claim 6
Dependent Claim
14 words
The bone cement of claim 1 wherein said emulsifying agent is sorbitan mono-oleate polyoxyethylene.
Claim 7
Dependent Claim
14 words
The bone cement of claim 7 wherein said emulsifying agent is sodium dihexyl sulfosuccinate.
Claim 8
Dependent Claim
27 words
A liquid monomer of an acrylic ester containing (a) erythromycin, or pharmaceutically acceptable salts thereof and (b) an emulsifying agent for erythromycin, or pharmaceutically acceptable salts thereof.
Claim 9
Dependent Claim
27 words
A liquid monomer of an acrylic ester containing (a) erythromycin, or pharmaceutically acceptable salts thereof and (b) an emulsifying agent for erythromycin, or pharmaceutically acceptable salts thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-02-12 | 1993-08-14 | 1994-02-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-02-12 | 1997-08-14 | 1998-02-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-02-12 | 2001-08-14 | 2002-02-13 | $7700.00 | Window Closed / Lapsed |