Patent US4892734A successfully refreshed from Google Patents.
US4892734A
Expired / Lapsed
US
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Dispensing paste for forming medicinal pellets
Assignee: QUINTECH PHARMACEUTICALS Inc
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Filing: 1988-03-31
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Granted: 1990-01-09
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Expires: 2008-03-31
Abstract
Abstract A process for aliquotting precise amounts of an active ingredient and a carrier for forming pellets is provided. The active ingredient and carrier are dispensed separately and then are mixed together. The mixture is combined with a liquid to form a paste. A precise amount of the paste is dispensed and the liquid is evaporated out of the paste leaving a dry, homogeneous mixture. The dry mixture then is formed into a pellet containing the active ingredient and the carrier in precise relative amounts.
Inventors
- 👤 Robert J. Leonard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:12
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K9/1682; A61K9/1694; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
58 words
A process for dispensing an active ingredient and a carrier for forming pellets containing said active ingredient and said carrier comprising, forming a paste from said active ingredient, said carrier and a liquid, dispensing said paste, causing said liquid to be evaporated out of said paste, leaving a dry mixture, and forming a pellet from said dry mixture.
Claim 2
Dependent Claim
58 words
A process for dispensing an active ingredient and a carrier for forming pellets containing said active ingredient and said carrier comprising, forming a paste from said active ingredient, said carrier and a liquid, dispensing said paste, causing said liquid to be evaporated out of said paste, leaving a dry mixture, and forming a pellet from said dry mixture.
Claim 3
Dependent Claim
82 words
A process for dispensing an active ingredient and a carrier for forming pellets containing said active ingredient and said carrier, comprising, dispensing a first amount of said active ingredient, dispensing a second amount of said carrier, mixing said first and second amounts together with a liquid to form a paste, dispensing said paste, causing said liquid to be evaporated out of said paste leaving a dry mixture of said active ingredient and said carrier, and forming a pellet from said dry mixture.
Claim 4
Dependent Claim
82 words
A process for dispensing an active ingredient and a carrier for forming pellets containing said active ingredient and said carrier, comprising, dispensing a first amount of said active ingredient, dispensing a second amount of said carrier, mixing said first and second amounts together with a liquid to form a paste, dispensing said paste, causing said liquid to be evaporated out of said paste leaving a dry mixture of said active ingredient and said carrier, and forming a pellet from said dry mixture.
Claim 5
Dependent Claim
39 words
A process as claimed in claim 2 wherein said active ingredient and said carrier are dispensed in relative amounts such that said active ingredient comprises at least 40% of the total amount of the active ingredient and carrier dispensed.
Claim 6
Dependent Claim
25 words
A process as claimed in claim 2 wherein said active ingredient and said carrier are mixed with a liquid that is a volatile organic solvent.
Claim 7
Dependent Claim
31 words
A process as claimed in claim 3 wherein said active ingredient is a steroid drug and wherein said steroid and said carrier are mixed with said liquid to form said paste.
Claim 8
Dependent Claim
31 words
A process as claimed in claim 3 wherein said active ingredient is a peptide drug and said peptide drug and said carrier are mixed with said liquid to form said paste.
Claim 9
Dependent Claim
50 words
A process as claimed in claim 3 wherein said carrier is selected from the group consisting of cholesterol, derivatives of cholesterol, cholesteric esters and derivatives of cholesteric esters and wherein said active ingredient and at least one carrier from said group are mixed with said liquid to form said paste.
Claim 10
Dependent Claim
39 words
A process as claimed in claim 7 wherein said active ingredient is selected from the group consisting of steroid drugs and peptide drugs and wherein said drug and said carrier are mixed with said liquid to form said paste.
Claim 11
Dependent Claim
34 words
A process as claimed in claim 1 wherein said active ingredient is norethindrone and said carrier is cholesterol and wherein said norethindrone and said cholesterol are mixed with said liquid to form said paste.
Claim 12
Dependent Claim
27 words
A process as claimed in claim 8 wherein said drug and said carrier are mixed with a liquid selected from the group consisting of alcohols and ethers.
Claim 13
Dependent Claim
48 words
A flowable, paste useful for dispensing an active ingredient and a carrier in precise relative amounts to form a medicinal pellet, said paste containing an effective portion of a drug as the active ingredient and a carrier, the drug and carrier homogeneously dispersed in a transitory, volatile liquid.
Claim 14
Dependent Claim
48 words
A flowable, paste useful for dispensing an active ingredient and a carrier in precise relative amounts to form a medicinal pellet, said paste containing an effective portion of a drug as the active ingredient and a carrier, the drug and carrier homogeneously dispersed in a transitory, volatile liquid.
Claim 15
Dependent Claim
37 words
A flowable paste as claimed in claim 11 wherein said carrier is present in an amount by weight of at least 15% relative to the amount of the drug, exclusive of the weight of the volatile liquid.
Claim 16
Dependent Claim
29 words
A flowable paste as claimed in claim 11 wherein said drug is present in an amount by weight of at least 40%, exclusive of the weight of the solvent.
Claim 17
Dependent Claim
33 words
A flowable paste as claimed in claim 11 wherein said carrier is selected from the group consisting of, sterols, cholesterol, cholesterol acetate, cholesterol chloride, cholesteric esters, and derivatives of cholesterol and cholesteric esters.
Claim 18
Dependent Claim
23 words
A flowable paste as claimed in claim 11 wherein said drug is selected from the group consisting of steroid drugs and peptide drugs.
Claim 19
Dependent Claim
23 words
A flowable paste as claimed in claim 13 wherein said drug is selected from the group consisting of steroid drugs and peptide drugs.
Claim 20
Dependent Claim
23 words
A flowable paste as claimed in claim 14 wherein said drug is selected from the group consisting of steroid drugs and peptide drugs.
Claim 21
Dependent Claim
17 words
A flowable paste as claimed in claim 17 wherein said liquid is an alcohol or an ether.
Claim 22
Dependent Claim
17 words
A flowable paste as claimed in claim 17 wherein the drug is norethindrone or growth-hormone releasing hormone.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-08 | 1993-07-10 | 1994-01-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-08 | 1997-07-10 | 1998-01-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-08 | 2001-07-10 | 2002-01-09 | $7700.00 | Window Closed / Lapsed |