Patent US4891593A successfully refreshed from Google Patents.
US4891593A
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Methods of obtaining images representing the distribution of paramagnetic molecules in solution
Assignee: BTG International Ltd
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Filing: 1988-08-04
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Granted: 1990-01-02
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Expires: 2008-08-04
Abstract
Abstract An image of the distribution of the molecules of a paramagnetic substance in solution obtained by exciting EPR resonance in the solute and obtaining an NMR image of selected nuclei (e.g. protons) in the solvent.
Inventors
- 👤 John Lurie
- 👤 David M. Bussell
- 👤 John R. Mallard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:42
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/60; G01R33/62
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
87 words
A method of obtaining image information representing the distribution of paramagnetic molecules in solution comprising the steps of: (1) applying radio-frequency radiation to excite EPR resonance in the solute and obtaining an NMR image signal of selected nuclei of the solvent, the signal from those selected nuclei which interact with electrons excited by the rf radiation being enhanced; (2) obtaining a separate NMR image signal of said selected nuclei which is unenhanced; and (3) deriving image information representing the difference between the enhanced and unenhanced image signals.
Claim 2
Independent Claim
87 words
A method of obtaining image information representing the distribution of paramagnetic molecules in solution comprising the steps of: (1) applying radio-frequency radiation to excite EPR resonance in the solute and obtaining an NMR image signal of selected nuclei of the solvent, the signal from those selected nuclei which interact with electrons excited by the rf radiation being enhanced; (2) obtaining a separate NMR image signal of said selected nuclei which is unenhanced; and (3) deriving image information representing the difference between the enhanced and unenhanced image signals.
Claim 3
Dependent Claim
15 words
The method as claimed in claim 1 in which the said selected nuclei are protons.
Claim 4
Dependent Claim
14 words
The method as claimed in claim 1 which the said radio-frequency radiation is pulsed.
Claim 5
Dependent Claim
21 words
The method as claimed in claim 3 in which the NMR image signal is obtained by an NMR imaging pulse sequence.
Claim 6
Dependent Claim
28 words
The method as claimed in claim 4 in which the pulses of the said pulsed radio-frequency radiation end before each pulse of the said NMR imaging pulse sequence.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-01 | 1993-07-03 | 1994-01-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-01 | 1997-07-03 | 1998-01-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-01 | 2001-07-03 | 2002-01-02 | $7700.00 | Window Closed / Lapsed |