Catheter guide wire

Claim 2

A catheter guide wire designed for use in guiding a catheter to a target site along a tortuous vessel path which is at least about 20 cm long and which has sharp-bend vessel junctions, requiring advancing a distal portion of the wire across the junction, then sliding the catheter over the advanced portion of the wire, said guide wire comprising a flexible, torqueable proximal wire section between about 50-250 cm in length and formed of a proximal wire core segment having an outer diameter of between about 10-40 mils, a more flexible intermediate section having a length between about 20-60 cm and formed from an intermediate wire-core segment having a reduced diameter of between about 4-20 mils and between about 10%-50% of the core's proximal segment, and a flexible polymer tube covering which encases the intermediate core segment and which provides column strength thereto, and a most flexible distal end section have a length between about 1-10 cm and formed from a distal wire core segment having a reduced diameter of between about 2-6 mils, and a flexible sleeve covering the distal end segment and providing column strength thereto, said intermediate section having a polymer surface which makes the section more lubriciuos than the adjacent distal end segment and said wire core.

Claim 3

The guide wire of claim 1, wherein the proximal wire core segment is between about 10-20 mils, the intermediate wire core segment has an average diameter of between about 4-8 mils, and the distal wire core segment has a diameter of between about 2-5 mils.

Claim 4

The guide wire of claim 2, wherein the intermediate wire core segment has a substantially constant diameter along a major portion of its length, and includes a relatively short region of taper between the constant-diameter portions of the distal and intermediate wire core segment.

Claim 5

The guide wire of claim 2, wherein the distal wire core segment has a substantially continuous taper along its length.

Claim 6

The guide wire of claim 1, which has a substantially constant outer diameter along its length.

Claim 7

The guide wire of claim 1, wherein said covering is composed of an inner polymer tube formed from one polymer material, and a surface coating formed from a second, more lubricious polymer material.

Claim 8

The guide wire of claim 6, wherein the intermediate section has an outer diameter which is substantially the same as that of the distal wire core segment.

Claim 9

The guide wire of claim 1, wherein said sleeve is a helical coil formed from a radio-opaques metal selected from the group consisting of platinum and gold.

Claim 10

The guide wire of claim 8, wherein the distal end section has an outer diameter which is substantially the same as that of the intermediate section.

Claim 11

A catheter guide wire designed for use in guiding a catheter to a target site along a tortuous vessel path which is at least about 20 cm long and which has sharp-bend vessel junctions, requiring advancing a distal portion of the wire across the junction, then sliding the catheter over the advanced portion of the wire, said guide wire comprising a flexible, torqueable proximal wire section between about 50-250 cm in length and formed of a proximal wire core segment having an outer diameter of between about 10-20 mils, a more flexible intermediate section having a length between about 20-60 cm and formed, from an intermediate wire-core segment having an average reduced diameter of between about 4-8 mils and about 10-50% of the core's proximal segment, and a flexible polymer covering which encases the intermediate core segment, and provides column strength thereto, and a most flexible distal end section having a length between about 1-10 cm and formed from a distal wire core segment having a reduced diameter of between about 26 mils, and a flexible radio-opaque helical coil covering the distal end segment and providing column strength thereto, said intermediate section having a hydrophilic polymer surface which makes the section more lubricious than the adjacent distal end segment, and said wire core.

Claim 12

A catheter guide wire designed for use in guiding a catheter to a target site along a tortuous vessel path which is at least about 20 cm long and which has sharp-bend vessel junctions, requiring advancing a distal portion of the wire across the junction, then sliding the catheter over the advanced portion of the wire, said guide wire comprising a flexible, torqueable proximal wire section between about 50-250 cm in length and formed of a proximal wire core segment having an outer diameter of between about 10-20 mils, a more flexible intermediate section having a length between about 20-60 cm and formed, from an intermediate wire-core segment having an average reduced diameter of between about 4-8 mils and about 10-50% of the core's proximal segment, and a flexible polymer covering which encases the intermediate core segment, and provides column strength thereto, and a most flexible distal end section having a length between about 1-10 cm and formed from a distal wire core segment having a reduced diameter of between about 26 mils, and a flexible radio-opaque helical coil covering the distal end segment and providing column strength thereto, said intermediate section having a hydrophilic polymer surface which makes the section more lubricious than the adjacent distal end segment, and said wire core.

Claim 13

A catheter device for use in accessing a target site along a tortuous vessel path which is at least about 20 cm long and which has sharp-bend vessel junctions, said device comprising a guide wire having (i) a flexible, torqueable proximal wire section between about 50-250 cm in length and formed of a proximal wire core segment having an outer diameter of between about 10-40 mils, (ii) a more flexible intermediate section having a length between about 20-60 cm and formed from an intermediate wire-core segment having a reduced diameter of between about 4-20 mils and between about 10%-50% of the core's proximal segment, and a flexible polymer covering which encases the intermediate core segment, providing column strength thereto, and (iii) a most flexible distal end section having a length between about 1-10 cm and formed from a distal wire core segment having a reduced diameter of between about 2-6 mils, and a flexible sleeve covering the distal end segment and providing column strength thereto, where the intermediate section has a low-friction polymer surface which makes the section more lubricious than the adjacent distal end segment, and a catheter designed to be advanced over the wire, as the wire is moved toward the target site.

Claim 14

A catheter device for use in accessing a target site along a tortuous vessel path which is at least about 20 cm long and which has sharp-bend vessel junctions, said device comprising a guide wire having (i) a flexible, torqueable proximal wire section between about 50-250 cm in length and formed of a proximal wire core segment having an outer diameter of between about 10-40 mils, (ii) a more flexible intermediate section having a length between about 20-60 cm and formed from an intermediate wire-core segment having a reduced diameter of between about 4-20 mils and between about 10%-50% of the core's proximal segment, and a flexible polymer covering which encases the intermediate core segment, providing column strength thereto, and (iii) a most flexible distal end section having a length between about 1-10 cm and formed from a distal wire core segment having a reduced diameter of between about 2-6 mils, and a flexible sleeve covering the distal end segment and providing column strength thereto, where the intermediate section has a low-friction polymer surface which makes the section more lubricious than the adjacent distal end segment, and a catheter designed to be advanced over the wire, as the wire is moved toward the target site.

Claim 15

The device of claim 11, wherein the catheter includes a relatively stiff proximal tube segment dimensioned to track the wire along the proximal end section thereof, and a relatively flexible distal tube segment constructed and dimensioned to track the wire along the intermediate and distal end sections thereof.

Claim 16

The device of claim 12, wherein catheter has a substantially constant-diameter inner lumen, and the wire has a substantially constant diameter along its length.

Claim 17

The device of claim 13, wherein the clearance between the outer surface of the wire and the inner lumen of the catheter is between about 2-5 mils.

Claim 18

The device of claim 12, wherein the clearance between the outer surface of the wire and the inner lumen of the catheter is between about 2-5 mils.