US4880006A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bone ingrowth chamber
Assignee: Nobel Biocare AB
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Filing: 1987-11-23
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Granted: 1989-11-14
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Expires: 2007-11-23
Abstract
Abstract An apparatus for studying the bone formation or bone ingrowth in an implant, in response to locally administered test substances of different types, is made of bio-compatible material, preferably pure titanium, and is implanted in living bone tissue, primarily for animal experiment activities. The apparatus has an outer portion with a central recess in which an inner portion is removably inserted. The two portions form, in the assembled state, a bone tissue ingrowth channel which is exposed when the inner portion is removed, whereby allowing examination of tissue which has grown into the channel. The inner portion includes a reservoir for the test substance whose bone formation promoting properties are to be tested. The reservoir is connected to the bone tissue ingrowth channel through a capillary aperture, so-called diffusion capillary, for supply of the test substance without simultaneous liquid flow.
Inventors
- 👤 Tomas Albrektsson
- 👤 Per Aspenberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 22:57
CPC Classifications
A; A61; A61M; A61M39/00; A61M39/02; A61M39/0247; A61B; A61B10/00; A61B17/00; A61B17/56; A61B17/58; A61B17/68; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2/30; A61F2/46; A61F2/468; A61B10/02; A61B10/0233; A61B10/025; A61F2/30767; A61F2002/2817; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30224; A61F2002/30235; A61F2002/30316; A61F2002/30329; A61F2002/30433; A61F2002/30667; A61F2002/30677; A61F2220/00; A61F2220/0025; A61F2220/0041; A61F2230/00; A61F2230/0063; A61F2230/0069; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00023; A61F2310/00389; A61F2310/00395; A61F2310/00407; A61M2039/025; A61M2039/0267; A61M2039/0276; A61M2039/0294; A61M2210/00; A61M2210/02; Y; Y10; Y10S; Y10S623/00; Y10S623/912; Y10S623/914
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
149 words
An apparatus of a bio-compatible material for implantation in a living bone tissue and for studying bone tissue formation growth in an implant in response to a locally administered test substance, said apparatus comprising; an outer portion with a central recess extending therethrough and a removable inner portion insertable in said central recess; means provided in at least a bottom wall of said outer portion cooperating with a bottom wall of said inner portion to form a bone tissue ingrowth channel when said inner portion is fully inserted into said central recess, said channel being exposable for access thereto when said inner portion is removed upwardly, thereby allowing examination of said bone tissue ingrowth in said channel; and a reservoir provided in said inner portion, said reservoir including means for fluid communication with said bone tissue ingrowth channel for supplying said test substance to said bone tissue ingrowth channel.
Claim 2
Independent Claim
149 words
An apparatus of a bio-compatible material for implantation in a living bone tissue and for studying bone tissue formation growth in an implant in response to a locally administered test substance, said apparatus comprising; an outer portion with a central recess extending therethrough and a removable inner portion insertable in said central recess; means provided in at least a bottom wall of said outer portion cooperating with a bottom wall of said inner portion to form a bone tissue ingrowth channel when said inner portion is fully inserted into said central recess, said channel being exposable for access thereto when said inner portion is removed upwardly, thereby allowing examination of said bone tissue ingrowth in said channel; and a reservoir provided in said inner portion, said reservoir including means for fluid communication with said bone tissue ingrowth channel for supplying said test substance to said bone tissue ingrowth channel.
Claim 3
Dependent Claim
55 words
An apparatus according to claim 1, wherein said means forming said bone tissue ingrowth channel includes a first groove formed in the bottom wall of said outer portion and a second groove corresponding to said first groove and aligned therewith to form said channel when said inner portion is fully inserted into said central recess.
Claim 4
Dependent Claim
18 words
The apparatus as claimed in claim 1, wherein said inner and outer portions are made of pure titanium.
Claim 5
Dependent Claim
31 words
The apparatus as claimed in claim 1, wherein said inner and outer portions have at least those surfaces which come into direct contact with the bone tissue, coated with pure titanium.
Claim 6
Dependent Claim
31 words
The apparatus as claimed in claim 2, wherein said inner and outer portions have at least those surfaces which come into direct contact with the bone tissue, coated with pure titanium.
Claim 7
Dependent Claim
51 words
The apparatus as claimed in claim 1, wherein said reservoir includes a cavity provided in said inner portion and extending therethrough to communicate with said bone tissue ingrowth channel and wherein said means for fluid communication includes a capillary aperture for the supply of the test substance without simultaneous liquid flow.
Claim 8
Dependent Claim
51 words
The apparatus as claimed in claim 2, wherein said reservoir includes a cavity provided in said inner portion and extending therethrough to communicate with said bone tissue ingrowth channel and wherein said means for fluid communication includes a capillary aperture for the supply of the test substance without simultaneous liquid flow.
Claim 9
Dependent Claim
50 words
The apparatus as claimed in claim 6, wherein said reservoir includes an elongate, diagonally disposed cavity of substantially the same orientation as said bone tissue ingrowth channel and two holes extending through said outer and inner portions for receiving locking screws for fixed interlocking of said inner and outer portions.
Claim 10
Dependent Claim
23 words
The apparatus as claimed in claim 8, wherein said two holes extend through said inner portion on opposite sides of said elongate cavity.
Claim 11
Dependent Claim
36 words
The apparatus as claimed in claim 9, wherein said reservoir is upwardly covered by a cover plate which is locked to the upper end surface of said inner portion by locking screws received in said holes.
Claim 12
Dependent Claim
36 words
The apparatus as claimed in claim 10, wherein said cover plate is provided with two openings at the location above said liquid reservoir for receiving hoses for supply and removal (drainage), respectively, of the test substance.
Claim 13
Dependent Claim
37 words
The apparatus as claimed in claim 11, wherein said reservoir is connected to a subcutaneous, osmotically acting minipump for continuous supply of the test substance to said bone tissue ingrowth channel during a predetermined period of time.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-11-13 | 1993-05-15 | 1993-11-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-11-13 | 1997-05-15 | 1997-11-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-11-13 | 2001-05-15 | 2001-11-14 | $7700.00 | Window Closed / Lapsed |