Patent FR410515A successfully refreshed from Google Patents.
US4876332A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polypeptides with type IV collagen activity
Assignee: University of Minnesota Twin Cities
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Filing: 1987-10-08
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Granted: 1989-10-24
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Expires: 2007-10-08
Abstract
Abstract A composition which can bind heparin and promote cellular adhesion is provided which consists essentially of a polypeptide of the formula: met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg, thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr-met, asn-pro-leu-cys-pro-pro-gly-thr-lys-ile-leu, or mixtures thereof. Medical devices such as prosthetic implants, percutaneous devices, bandages and cell culture substrates coated with the polypeptide composition are also provided.
Inventors
- 👤 Effie C. Tsilibary
- 👤 Leo T. Furcht
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:28
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/78; A; A61; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/28; A61L15/32; A61L27/00; A61L27/14; A61L27/22; A61L27/227; A61L27/50; A61L27/507; C12; C12N; C12N5/00; C12N5/0068; A61K; A61K38/00; C12N2533/00; C12N2533/50; C12N2533/54
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
17 words
A composition consisting essentially of a polypeptide of the formula: met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg, thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr met, asn-pro-leu-cys-pro-gly-thr-lys-ile-leu, or mixtures thereof.
Claim 2
Dependent Claim
17 words
A composition consisting essentially of a polypeptide of the formula: met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg, thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr met, asn-pro-leu-cys-pro-gly-thr-lys-ile-leu, or mixtures thereof.
Claim 3
Dependent Claim
6 words
A polypeptide of the formula: met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg.
Claim 4
Dependent Claim
6 words
A polypeptide of the formula: met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg.
Claim 5
Dependent Claim
6 words
A polypeptide of the formula: thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr-met.
Claim 6
Dependent Claim
6 words
A polypeptide of the formula: thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr-met.
Claim 7
Dependent Claim
6 words
A polypeptide of the formula: asn-pro-leu-cry-pro-pro-gly-thr-lys-ile-leu.
Claim 8
Dependent Claim
6 words
A polypeptide of the formula: asn-pro-leu-cry-pro-pro-gly-thr-lys-ile-leu.
References Cited (Backward Citations)
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Cited
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Cited
US4677058A
Cited
US4591456A
Cited
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Cited
US4746729A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-10-23 | 1993-04-24 | 1993-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-10-23 | 1997-04-24 | 1997-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-10-23 | 2001-04-24 | 2001-10-24 | $7700.00 | Window Closed / Lapsed |