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US4871542A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and apparatus useful for delivering medicinal compositions into the bladder and urinary tract

Assignee: Ferring Service Center NV
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Filing: 1987-04-30
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Granted: 1989-10-03
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Expires: 2007-04-30
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Abstract

Abstract The present invention provides a method and an apparatus for delivering medicinals to animal or human bladders. The apparatus is a polymeric, minicellular container surrounding an internal reservoir which contains the medicinal. The apparatus delivers the medicinal to the bladder at a prolonged, continuous and controlled rate.

Inventors

  • 👤 Hans Vilhardt

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 19:16
CPC Classifications
A; A61; A61M; A61M31/00; A61M31/002; A61K; A61K9/00; A61K9/0012; A61K9/0034; A61K9/0087; A61K9/0092

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 75 words
A method for delivering medicinals to animal or human bladders and urinary tracts which comprises: inserting into said bladder a polymeric, minicellular porous container, said container comprising an internal reservoir containing said medicinal and a flotation means effective to keep said container floating above the bladder outlet, wherein said medicinal diffuses through the pores of said container and into said bladder and urinary tract in an effective amount at a programmed, continuous, and controlled rate.
Claim 2
Independent Claim 75 words
A method for delivering medicinals to animal or human bladders and urinary tracts which comprises: inserting into said bladder a polymeric, minicellular porous container, said container comprising an internal reservoir containing said medicinal and a flotation means effective to keep said container floating above the bladder outlet, wherein said medicinal diffuses through the pores of said container and into said bladder and urinary tract in an effective amount at a programmed, continuous, and controlled rate.
Claim 3
Dependent Claim 17 words
The method of claim 1 wherein the size of the minicellular pores regulates diffusion of the medicinal.
Claim 4
Dependent Claim 18 words
The method of claim 1 wherein the floatation means is an air bubble or series of air bubbles.
Claim 5
Dependent Claim 17 words
The method of claim 1 wherein the polymeric, minicellular porous container is formed into an O-shaped ring.
Claim 6
Dependent Claim 13 words
The method of claim 1 wherein the polymeric, minicellular porous container is biodegradable.
Claim 7
Dependent Claim 15 words
The method of claim 1 wherein the polymeric, minicellular porous container is made of polypropylene.
Claim 8
Dependent Claim 26 words
The method of claim 1 wherein the medicinal is selected from the group consisting of anticancer agents, hormones, anesthetics, antiseptics, antibacterials, antibiotics, antivirals, antimicrobials, and diagnostics.
Claim 9
Dependent Claim 11 words
The method of claim 1 wherein the medicinal is Mitomycin C.
Claim 10
Independent Claim 87 words
A method of delivering medicinals to animal or human bladders and urinary tracts which comprises: a. inserting a sealed polymeric container with a porous wall containing said medicinal and an isolated compartment containing a solution of osmotically active particles into the bladder; b. contacting said osmotically active particles with a liquid such that the osmotically active particles imbibe the liquid and expand, thereby pressing the medicinal out of said sealed polymeric container; and c. maintaining the medicinal in the bladder at a programmed, continuous and controlled rate.
Claim 11
Independent Claim 87 words
A method of delivering medicinals to animal or human bladders and urinary tracts which comprises: a. inserting a sealed polymeric container with a porous wall containing said medicinal and an isolated compartment containing a solution of osmotically active particles into the bladder; b. contacting said osmotically active particles with a liquid such that the osmotically active particles imbibe the liquid and expand, thereby pressing the medicinal out of said sealed polymeric container; and c. maintaining the medicinal in the bladder at a programmed, continuous and controlled rate.
Claim 12
Dependent Claim 13 words
The method of claim 9 wherein the device is constructed from buoyant material.
Claim 13
Dependent Claim 12 words
The method of claim 9 wherein said device contains a floatation means.
Claim 14
Dependent Claim 18 words
The method of claim 11 wherein said floatation means is an air bubble or series of air bubbles.
Claim 15
Dependent Claim 14 words
The method of claim 9 wherein said device is formed into an O-shaped ring.
Claim 16
Dependent Claim 14 words
The method of claim 9 wherein said device is made of a biodegradable material.
Claim 17
Dependent Claim 26 words
The method of claim 9 wherein the medicinal is selected from the group consisting of anticancer agents, hormones, anesthetics, antiseptics, antibacterials, antibiotics, antivirals, antimicrobials, and diagnostics.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-10-02 1993-04-03 1993-10-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-10-02 1997-04-03 1997-10-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-10-02 2001-04-03 2001-10-03 $7700.00 Window Closed / Lapsed

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