Abstract The invention involves the use of absorbable or absorbable/nonabsorbable components to fabricate textile vascular grafts of all sizes and specifically for repair of the peripheral vascular system and for coronary bypass use. The bioabsorbable component of the graft fosters increased tissue ingrowth into the graft as compared to conventional 100% nonabsorbable grafts. Increased tissue ingrowth leads to greater patency through formation of a vascularized neointima and less tendency to be aneurysmal through formation of a suitable adventitia. The absorbable component can be a variety of materials, including PGA, MAXOM TM , etc., whereas the nonabsorbable component (to be used as the backbone) can be new materials, e.g. NOVAFIL TM , or more conventional polymers, including polyester, polyamide or polypropylene. The vascular grafts further comprise an external support helically wrapped therearound and permanently attached to the outside surface.
A tubular article useful in prosthetic surgery comprising a plurality of at least three different fibers, the first and second fibers manufactured from two different absorbable polymers, and the third fiber manufactured from a nonabsorbable polymer; and further comprising an external support helically wrapped about and permanently adhered to the outside surface of the article.
Claim 2
Dependent Claim
55 words
A tubular article useful in prosthetic surgery comprising a plurality of at least three different fibers, the first and second fibers manufactured from two different absorbable polymers, and the third fiber manufactured from a nonabsorbable polymer; and further comprising an external support helically wrapped about and permanently adhered to the outside surface of the article.
Claim 3
Dependent Claim
94 words
A tubular article useful in prosthetic surgery comprising a plurality of at least three different fibers, the first and second fibers manufactured from two different absorbable polymers, and the third fiber manufactured from a nonabsorbable polymer; and further comprising an external support, the external support having at least one fiber and means for permanently adhereing the at least one fiber of said support to the outside surface of the article, whereby said fiber of said support is helically wrapped about said outside surface and attached to said surface by the means for permanently adhering.
Claim 4
Dependent Claim
94 words
A tubular article useful in prosthetic surgery comprising a plurality of at least three different fibers, the first and second fibers manufactured from two different absorbable polymers, and the third fiber manufactured from a nonabsorbable polymer; and further comprising an external support, the external support having at least one fiber and means for permanently adhereing the at least one fiber of said support to the outside surface of the article, whereby said fiber of said support is helically wrapped about said outside surface and attached to said surface by the means for permanently adhering.
Claim 5
Dependent Claim
20 words
The article of claim 2 further comprising the external support having at least one fiber manufactured from an absorbable polymer.
Claim 6
Dependent Claim
20 words
The article of claim 3 wherein the absorbable polymer of the external support comprises at least one trimethylene carbonate linkage.