Patent US4856188A successfully refreshed from Google Patents.
US4856188A
Expired / Lapsed
US
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Method for making disposable and/or replenishable transdermal drug applicators
Assignee: Drug Delivery Systems Inc
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Filing: 1987-10-07
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Granted: 1989-08-15
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Expires: 2007-10-07
Abstract
Abstract Applicators for the electrophoretic and/or electroosmotic deposition of a medicament across the skin and into the blood stream. The applicator includes a plurality of drug reservoir electrodes, a battery, a plurality of folded members each having an electrically conductive coating on a flexible, non-conductive substrate in electrical contact with the battery and the drug reservoir electrodes, electrical current conditioning means, and a cover adhesively secured to the applicator.
Inventors
- 👤 Dan Sibalis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:45
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/325; A61M; A61M31/00; A61M31/002; A61M37/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0428; A61N1/0432; A61N1/044; A61N1/0436; A61N1/0448; Y; Y10; Y10T; Y10T29/00; Y10T29/49; Y10T29/49002; Y10T29/49117; Y10T29/49204; Y10T29/49208; Y10T29/4921
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
88 words
A method for making a replaceable disposable drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a release coated substrate; b. depositing on said substrate occlusive adhesive dam material to define drug reservoir compartments; c. laminating an open cell foam material to said substrate over said occlusive adhesive dam material so as to cause said dam material to penetrate and fill the full thickness of said open cell foam; and d. filling said plurality of drug reservoir compartments with drug electrolyte mixtures.
Claim 2
Independent Claim
88 words
A method for making a replaceable disposable drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a release coated substrate; b. depositing on said substrate occlusive adhesive dam material to define drug reservoir compartments; c. laminating an open cell foam material to said substrate over said occlusive adhesive dam material so as to cause said dam material to penetrate and fill the full thickness of said open cell foam; and d. filling said plurality of drug reservoir compartments with drug electrolyte mixtures.
Claim 3
Dependent Claim
44 words
The method of manufacturing a transdermal drug applicator which is electrically activated according to claim 1, further comprising the step of laminating together said replaceable drug reservoir with another drug reservoir and the lamination comprising a reinforcing scrim between the two drug reservoir layers.
Claim 4
Dependent Claim
44 words
The method of manufacturing a transdermal drug applicator which is electrically activated, according to claim 1, further comprising the step of laminating together said replaceable drug reservoir with another drug reservoir and the lamination comprising a semipermeable membrane between the two drug reservoir layers.
Claim 5
Independent Claim
66 words
The method of manufacturing a transdermal drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a web substrate continuously fed from rolled stock material; and b. applying to said substrate a plurality of drug reservoirs and occlusive dam material in a continuous or repeated pattern; whereby replaceable/disposable drug reservoirs are formed with said dam material disposed between said drug reservoirs.
Claim 6
Independent Claim
66 words
The method of manufacturing a transdermal drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a web substrate continuously fed from rolled stock material; and b. applying to said substrate a plurality of drug reservoirs and occlusive dam material in a continuous or repeated pattern; whereby replaceable/disposable drug reservoirs are formed with said dam material disposed between said drug reservoirs.
Claim 7
Dependent Claim
25 words
The method according to claim 4, wherein two drug reservoirs assemblies are combined in an aligned back-to-back fashion to form a single transdermal drug applicator.
Claim 8
Dependent Claim
18 words
The method according to claim 4, wherein said drug reservoirs form a quilt pattern of multiple drug reservoirs.
Claim 9
Dependent Claim
16 words
The method according to claim 4, wherein web material is provided to reinforce said drug reservoirs.
Claim 10
Dependent Claim
18 words
The method according to claim 4, wherein a semi-permeable membrane is provided in juxtaposition to said drug reservoir.
Claim 11
Independent Claim
74 words
The method of manufacturing a transdermal drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a web substrate continuously fed from rolled stock material; b. laminating to said substrate a foam material forming drug reservoirs, as well as occlusive dam material between said drug reservoirs so as to occupy the full depth of said foam material; and c. filling said drug reservoirs with one or more drug/gel mixtures.
Claim 12
Independent Claim
74 words
The method of manufacturing a transdermal drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a web substrate continuously fed from rolled stock material; b. laminating to said substrate a foam material forming drug reservoirs, as well as occlusive dam material between said drug reservoirs so as to occupy the full depth of said foam material; and c. filling said drug reservoirs with one or more drug/gel mixtures.
Claim 13
Dependent Claim
23 words
The method of claim 9, wherein said web substrate comprises a release liner which is discarded when said drug reservoir is employed transdermally.
Claim 14
Dependent Claim
21 words
The method of claim 9, further comprising the step of laminating together two drug reservoirs to form a thicker drug reservoir.
Claim 15
Dependent Claim
15 words
The method of claim 11, wherein said two drug reservoirs are separated by reinforcing means.
Claim 16
Dependent Claim
16 words
The method of claim 11, wherein said two drug reservoirs are separated by a semipermeable membrane.
Claim 17
Independent Claim
62 words
The method of manufacturing a transdermal drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a release coated substrate; b. laminating a foam material to said substrate so as to form drug reservoir compartments as well as occlusive dam material between said drug reservoirs; c. filing said drug reservoir compartments with one or more drug/gel mixtures.
Claim 18
Independent Claim
62 words
The method of manufacturing a transdermal drug reservoir for an electrically powered transdermal drug applicator, comprising the steps of: a. providing a release coated substrate; b. laminating a foam material to said substrate so as to form drug reservoir compartments as well as occlusive dam material between said drug reservoirs; c. filing said drug reservoir compartments with one or more drug/gel mixtures.
Claim 19
Dependent Claim
26 words
The method according to claim 14, further comprising the step of laiminating together two drug reservoirs with a reinforcing material disposed between the two drug reservoirs.
Claim 20
Dependent Claim
26 words
The method according to claim 14, further comprising the step of laminating together two drug reservoirs with a semipermeable membrane disposed between the two drug reservoirs.
References Cited (Backward Citations)
DE2257079A1
Cited
US4063352A
Cited
US4365634A
Cited
US4441500A
Cited
US4409981A
Cited
US4622031A
Cited
US4640289A
Cited
US4731926A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-08-14 | 1993-02-13 | 1993-08-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-08-14 | 1997-02-13 | 1997-08-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-08-14 | 2001-02-13 | 2001-08-15 | $7700.00 | Window Closed / Lapsed |