Kink resistant catheter

Claim 2

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, the cannula being of a material selected such that an inner cross-section of the duct increases to form an enlarged duct cross-section when at least a part of the distal end portion is inserted through the skin and into a blood vessel of a living subject and maintained therein and/or when the duct is contacted by an aqueous liquid for a period of time sufficient for the enlarged duct cross-section to form, an improvement comprising: where in the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position.

Claim 3

A cannula as set forth in claim 1, wherein the inner passageway has an inside cross-section substantially equal to or greater than the enlarged duct cross-section at the distal end portion.

Claim 4

A cannula as set forth in claim 1, wherein the reinforcing tube is of a polymeric material.

Claim 5

A cannula as set forth in claim 1, wherein the reinforcing tube is of a plastic material.

Claim 6

A cannula as set forth in claim 1, wherein the cannula is of a material having a 2.5% Secant modulus which reduces more than about 3:1 upon formation of the enlarged duct cross-section.

Claim 7

A cannula as set forth in claim 1, wherein the cannula is of a material through which medicaments can diffuse and wherein the reinforcing tube is of a material substantially impervious to medicaments.

Claim 8

A cannula as set forth in claim 1, wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and wherein the reinforcing tube terminates at the end of taper location.

Claim 9

A cannula as set forth in claim 7, wherein the tapered section is tapered at an angle of less than about 45°.

Claim 10

A cannula as set forth in claim 7, wherein said reinforcing tube is of a polymeric material.

Claim 11

A cannula as set forth in claim 7, wherein said reinforcing tube is of a plastic material.

Claim 12

A cannula as set forth in claim 7, wherein said cannula is of a material through which medicaments can diffuse and wherein said reinforcing tube is of a material substantially impervious to medicaments.

Claim 13

A cannula as set forth in claim 7, wherein the tapered section is tapered at an angle of less than about 15°.

Claim 14

A cannula as set forth in claim 7, wherein the tapered section is tapered at an angle of less than about 5°.

Claim 15

A cannula as set forth in claim 1, wherein the cannula is an over-the-needle type cannula.

Claim 16

A cannula as set forth in claim 1, wherein the inner passageway has an inside cross-section substantially equal to said enlarged duct cross-section.

Claim 17

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, the cannula being of a material selected such that an inner cross-section of the duct increases to form an enlarged duct cross-section when at least a part of the distal end portion is inserted through the skin and into a blood vessel of a living subject and maintained therein and/or when the duct is contacted by an aqueous liquid for a period of time sufficient for the enlarged duct cross-section to form, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and wherein the

Claim 18

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, the cannula being of a material selected such that an inner cross-section of the duct increases to form an enlarged duct cross-section when at least a part of the distal end portion is inserted through the skin and into a blood vessel of a living subject and maintained therein and/or when the duct is contacted by an aqueous liquid for a period of time sufficient for the enlarged duct cross-section to form, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and wherein the

Claim 19

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct there through from the distal end portion to the proximal end portion, the cannula being of a material selected such that an inner cross-section of the duct increases to form an enlarged duct cross-section when at least a part of the distal end portion is inserted through the skin and in to a blood vessel of a living subject and maintained there in and/or when the duct is contacted by an aqueous liquid for a period of time sufficient for the enlarged duct cross-section to form, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and wherein the reinforcing tube terminates at the end of taper location; and wherein said cannula is of a material having a 2.5% Secant modulus which reduces more than about 3:1 upon formation of said enlarged duct cross-section.

Claim 20

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct there through from the distal end portion to the proximal end portion, the cannula being of a material selected such that an inner cross-section of the duct increases to form an enlarged duct cross-section when at least a part of the distal end portion is inserted through the skin and in to a blood vessel of a living subject and maintained there in and/or when the duct is contacted by an aqueous liquid for a period of time sufficient for the enlarged duct cross-section to form, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and wherein the reinforcing tube terminates at the end of taper location; and wherein said cannula is of a material having a 2.5% Secant modulus which reduces more than about 3:1 upon formation of said enlarged duct cross-section.

Claim 21

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position a long the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel and where in the cannula is of a material which softens on being inserted into a living subject; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position.

Claim 22

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position a long the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel and where in the cannula is of a material which softens on being inserted into a living subject; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position.

Claim 23

A cannula as set forth in claim 18, wherein the inner passageway has an inside cross-section substantially equal to or greater than the duct cross-section at the distal end portion.

Claim 24

A cannula as set forth in claim 18, wherein the reinforcing tube is of a polymeric material.

Claim 25

A cannula as set forth in claim 18, wherein the reinforcing tube is of a plastic material.

Claim 26

A cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the cannula is of a material through which medicaments can diffuse and wherein the reinforcing tube is of a material substantially impervious to medicaments.

Claim 27

A cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the cannula is of a material through which medicaments can diffuse and wherein the reinforcing tube is of a material substantially impervious to medicaments.

Claim 28

A cannula as set forth in claim 18, wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and wherein the reinforcing tube terminates at the end of taper location.

Claim 29

A cannula as set forth in claim 23, further including: means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal the reinforcing tube.

Claim 30

A cannula as set forth in claim 24, wherein said means comprises a distal end of said reinforcing tube being thinned to a reduced thickness.

Claim 31

A cannula as set forth in claim 23, wherein the tapered section is tapered at an angle of less than about 45°.

Claim 32

A cannula as set forth in claim 26, wherein said angle is less than about 15°.

Claim 33

A cannula as set forth in claim 27, wherein said angle is less than about 5°.

Claim 34

A cannula as set forth in claim 23, wherein the tapered section is tapered at an angle at less than about 15°.

Claim 35

A cannula as set forth in claim 23, wherein the tapered section is tapered at an angle of less than about 5°.

Claim 36

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, and improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position, said reinforcing tube having a 2.5% Secant modulus between about 3450 and about 48,000 N/cm 2 .

Claim 37

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, and improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position, said reinforcing tube having a 2.5% Secant modulus between about 3450 and about 48,000 N/cm 2 .

Claim 38

A cannula as set forth in claim 18, wherein the cannula is an over-the-needle type cannula.

Claim 39

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the inner passageway has an inside cross-section substantially equal to said enlarged duct cross-section.

Claim 40

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; and wherein the inner passageway has an inside cross-section substantially equal to said enlarged duct cross-section.

Claim 41

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and where in the reinforcing tube terminates at the end of tapered location; and means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal the reinforcing tube, wherein said means comprises a cut away portion in said reinforcing tube beginning and extending proximally from where said reinforcing tube terminates.

Claim 42

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; wherein the cannula includes a tapered section extending from said position towards said proximal end portion to an end of taper location adjacent said position and where in the reinforcing tube terminates at the end of tapered location; and means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal the reinforcing tube, wherein said means comprises a cut away portion in said reinforcing tube beginning and extending proximally from where said reinforcing tube terminates.

Claim 43

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; wherein the cannula includes a tapered section extending from said position toward said proximal end portion to an end of taper location adjacent said position and wherein the reinforcing tube terminates at the end of taper location; means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal the reinforcing tube, said means comprising one or more fingers extending from where said reinforcing tube terminates towards said position.

Claim 44

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion to adjacent the position; wherein the cannula includes a tapered section extending from said position toward said proximal end portion to an end of taper location adjacent said position and wherein the reinforcing tube terminates at the end of taper location; means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal the reinforcing tube, said means comprising one or more fingers extending from where said reinforcing tube terminates towards said position.

Claim 45

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located distally from the hub, the cannula including a tapered section extending from said position toward said proximal end portion to an end of taper location adjacent said position, said tapered section being tapered at an angle of less than about 15°, the cannula being of a material which softens on being inserted into a living subject; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion distally beyond the hub towards the position, said reinforcing tube terminating at said end of taper location; and means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal of the reinforced tube.

Claim 46

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located distally from the hub, the cannula including a tapered section extending from said position toward said proximal end portion to an end of taper location adjacent said position, said tapered section being tapered at an angle of less than about 15°, the cannula being of a material which softens on being inserted into a living subject; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion distally beyond the hub towards the position, said reinforcing tube terminating at said end of taper location; and means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal of the reinforced tube.

Claim 47

A cannula as set forth in claim 36, wherein the inner passageway has an inside cross-section substantially equal to or greater than the duct cross-section at the distal end portion.

Claim 48

A cannula as set forth in claim 36, wherein the reinforcing tube is of a polymeric material.

Claim 49

A cannula as set forth in claim 36, wherein the reinforcing tube is of a plastic material.

Claim 50

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, and improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located distally from the hub, the cannula including a tapered section extending from said position toward said proximal end portion to an end of taper location adjacent said position, said tapered section being tapered at an angle of less than about 15°; a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion distally beyond the hub towards the position, said reinforcing tube terminating at said end of taper location; means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal of the reinforcing tube; and wherein the cannula is of a material through which medicaments can diffuse and wherein the reinforcing tube is of a material substantially impervious to medicaments.

Claim 51

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, and improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located distally from the hub, the cannula including a tapered section extending from said position toward said proximal end portion to an end of taper location adjacent said position, said tapered section being tapered at an angle of less than about 15°; a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion distally beyond the hub towards the position, said reinforcing tube terminating at said end of taper location; means for easing the transition from the unreinforced cannula distal of the reinforcing tube to the reinforced cannula proximal of the reinforcing tube; and wherein the cannula is of a material through which medicaments can diffuse and wherein the reinforcing tube is of a material substantially impervious to medicaments.

Claim 52

A cannula as set forth in claim 36, wherein said means comprises a cut away portion in said reinforcing tube, said cut away portion being cut away along a plane at a skew angle to said reinforcing tube, said cut away portion beginning and extending proximally form where said reinforcing tube terminates.

Claim 53

A cannula as set forth in claim 36, wherein said means comprises a distal end of said reinforcing tube being thinned to a reduced thickness.

Claim 54

A cannula as set forth in claim 36, wherein said angle is less than about 5°.

Claim 55

A cannula as set forth in claim 36, wherein the position is located such that when the distal end portion is inserted in the blood vessel the position is located beneath the skin short of the blood vessel.

Claim 56

A cannula as set forth in claim 36, wherein the cannula is an over-the-needle type cannula.

Claim 57

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located distally from the hub; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion distally beyond the hub towards the position; and means for easing the transition from the unreinforced cannula distal of the reinforced tube to the reinforced cannula proximal of the reinforced tube, said means comprising one or more fingers extending from where said reinforcing tube terminates towards said position.

Claim 58

In a cannula having a proximal end portion adapted to be connected to a hub, a distal end portion and a longitudinal duct therethrough from the distal end portion to the proximal end portion, an improvement comprising: wherein the cannula has a larger outer cross-section and the duct has a larger inner cross-section starting from the proximal end portion and continuing to a position along the cannula than have the cannula and the duct starting at the distal end portion and continuing to the position, the position being located distally from the hub; and further including: a reinforcing tube having an outer surface matingly held within the duct and having an inner passageway, the tube extending from the proximal end portion distally beyond the hub towards the position; and means for easing the transition from the unreinforced cannula distal of the reinforced tube to the reinforced cannula proximal of the reinforced tube, said means comprising one or more fingers extending from where said reinforcing tube terminates towards said position.