US4820514A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Low dosage of interferon to enhance vaccine efficiency
Assignee: Texas A&M University System
•
Filing: 1985-12-30
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Granted: 1989-04-11
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Expires: 2005-12-30
Abstract
Abstract A biologically active interferon can be administered to an animal in conjunction with the administration of a vaccine to improve the vaccine efficiency and allow the use of a smaller vaccination dose. This procedure will cause a less severe vaccine infection in the animal than if no interferon was administered.
Inventors
- 👤 Joseph M. Cummins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:04
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/39; A61K2039/555; A61K2039/55511; A61K2039/55522; Y; Y10; Y10S; Y10S435/00; Y10S435/811
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
55 words
In a method of enhancing the efficiency of a vaccine in a warm blooded vertebrate by administering to said vertebrate, in conjunction with the administration of a vaccine, a biologically active interferon, the improvement which comprises administering interferon orally to said vertebrate in a dosage no greater than 5 IU/lb of body weight per day.
Claim 2
Dependent Claim
55 words
In a method of enhancing the efficiency of a vaccine in a warm blooded vertebrate by administering to said vertebrate, in conjunction with the administration of a vaccine, a biologically active interferon, the improvement which comprises administering interferon orally to said vertebrate in a dosage no greater than 5 IU/lb of body weight per day.
Claim 3
Dependent Claim
17 words
The improvement of claim 1 where the dosage is about 1.0 IU/lb of body weight per day.
Claim 4
Dependent Claim
14 words
The improvement of claim 1, where the interferon is administered simultaneously with the vaccine.
Claim 5
Dependent Claim
24 words
The improvement of claim 1, where the interferon is administered within about one day before or after the time when the vaccine is administered.
Claim 6
Dependent Claim
38 words
The improvement of claim 1, where the interferon is administered on two or more of the days in the period consisting of the day before vaccine administration, the day of vaccine administration, and the day after vaccine administration.
Claim 7
Dependent Claim
12 words
The improvement of claim 1, where the interferon is human interferon alpha.
Claim 8
Dependent Claim
31 words
The improvement of claim 1, where the dosage is about 1.0 IU/lb of body weight per day, the interferon is human interferon alpha, and is administrated orally simultaneously with the vaccine.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-10 | 1992-10-10 | 1993-04-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-10 | 1996-10-10 | 1997-04-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-10 | 2000-10-10 | 2001-04-11 | $7700.00 | Window Closed / Lapsed |