US4497795A
Expired / Lapsed
US
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Method of regulating appetite and efficiency of food utilization employing interferon
Assignee: Texas A&M University System
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Filing: 1982-12-13
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Granted: 1985-02-05
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Expires: 2002-12-13
Abstract
Abstract The appetite of a warm-blooded vertebrate can be regulated by administering to the vertebrate a biological active fraction of interferon in an amount effective to modulate the vertebrate's food intake or efficiency in utilizing food. The appetite of a cow can be stimulated by the oral or intravenous administration of bovine fibroblast interferon or by interferon secreted nasally by the cow in response to inoculation with a vaccinal virus strain such as that of infectious bovine rhinotracheitis virus. The appetite of swine can be enhanced by oral administration of bovine fibroblast interferon.
Inventors
- 👤 Joseph M. Cummins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:20
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61K38/215; A23; A23K; A23K20/00; A23K20/10; A23K20/142; A23K20/147; A23K50/00; A23K50/30; A61K38/212; Y; Y10; Y10S; Y10S435/00; Y10S435/811
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
38 words
A method for increasing efficiency of food utilization of a warm-blooded vertebrate comprising administration to the warm-blooded vertebrate of a biologically active interferon in an amount effective to increase the efficiency in utilizing food for the warm-blooded vertebrate.
Claim 2
Independent Claim
38 words
A method for increasing efficiency of food utilization of a warm-blooded vertebrate comprising administration to the warm-blooded vertebrate of a biologically active interferon in an amount effective to increase the efficiency in utilizing food for the warm-blooded vertebrate.
Claim 3
Dependent Claim
12 words
The method of claim 1 wherein the warm-blooded vertebrate is a mammal.
Claim 4
Dependent Claim
12 words
The method of claim 1 wherein the warm-blooded vertebrate is a bird.
Claim 5
Dependent Claim
19 words
The method of claim 1, 2, or 3 wherein the interferon is isolated from cells of bovine species origin.
Claim 6
Dependent Claim
11 words
The method of claim 4 wherein the interferon is fibroblast interferon.
Claim 7
Independent Claim
27 words
A method for stimulating the appetite of cattle comprising administration to cattle an effective amount of a biologically active interferon found in cells of bovine species origin.
Claim 8
Independent Claim
27 words
A method for stimulating the appetite of cattle comprising administration to cattle an effective amount of a biologically active interferon found in cells of bovine species origin.
Claim 9
Dependent Claim
11 words
The method of claim 6 wherein the interferon is fibroblast interferon.
Claim 10
Dependent Claim
29 words
The method of claim 7 wherein each bovine is orally administered at least one dose of at least 10,000 units of bovine fibroblast interferon per kg of body weight.
Claim 11
Dependent Claim
35 words
The method of claim 7 wherein each bovine is intravenously administered daily for at least three days at least one dose of at least 4,000 units of bovine fibroblast interferon per kg of body weight.
Claim 12
Independent Claim
34 words
A method for stimulating the appetite of cattle comprising inoculation of a bovine with a vaccinal virus strain in an amount effective to cause nasal secretion by the bovine of a biologically active interferon.
Claim 13
Independent Claim
34 words
A method for stimulating the appetite of cattle comprising inoculation of a bovine with a vaccinal virus strain in an amount effective to cause nasal secretion by the bovine of a biologically active interferon.
Claim 14
Dependent Claim
19 words
The method of claim 10 wherein the vaccinal virus strain is a vaccinal strain of infectious bovine rhinotracheitis virus.
Claim 15
Dependent Claim
22 words
The method of claim 11 wherein each bovine is inoculated with at least about 10 4 TCID 50 of such vaccinal strain.
Claim 16
Independent Claim
27 words
A method for stimulating the appetite of swine comprising administration to swine an effective amount of a biologically active interferon found in cells of bovine species origin.
Claim 17
Independent Claim
27 words
A method for stimulating the appetite of swine comprising administration to swine an effective amount of a biologically active interferon found in cells of bovine species origin.
Claim 18
Dependent Claim
11 words
The method of claim 13 wherein the interferon is fibroblast interferon.
Claim 19
Dependent Claim
44 words
The method of claim 14 wherein the swine are piglets prior to weaning and the piglets are orally administered about 5,000 to about 50,000 units of bovine fibroblast interferon per kg of body weight per day for from one to five days before weaning.
Claim 20
Independent Claim
30 words
A method for increasing the efficiency of food utilization in chickens comprising administration to chickens an effective amount of a biologically active interferon found in cells of bovine species origin.
Claim 21
Independent Claim
30 words
A method for increasing the efficiency of food utilization in chickens comprising administration to chickens an effective amount of a biologically active interferon found in cells of bovine species origin.
Claim 22
Dependent Claim
11 words
The method of claim 16 wherein the interferon is fibroblast interferon.
Claim 23
Dependent Claim
34 words
The method of claim 17 wherein the chickens receive the bovine fibroblast interferon in their drinking water in an amount of from about 70 units to about 7,000 units per ml of drinking water.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-02-05 | 1988-08-06 | 1989-02-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-02-05 | 1992-08-06 | 1993-02-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-02-05 | 1996-08-06 | 1997-02-05 | $7700.00 | Window Closed / Lapsed |