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US4784659A
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Vessel and prosthesis impregnated with diisocyanate crosslinked gelatin
Assignee: Intermedicat GmbH
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Filing: 1987-03-03
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Granted: 1988-11-15
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Expires: 2007-03-03
Abstract
Abstract The invention relates to vessel prostheses formed from a porous vascular prosthesis impregnated with diisocyanate crosslinked gelatin for sealing the pores.
Inventors
- 👤 Peter Fleckenstein
- 👤 Heinz-Helmut Werner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:57
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/507; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/28; A61L27/34; Y; Y10; Y10S; Y10S128/00; Y10S128/08; Y10S623/00; Y10S623/901; Y10S623/92; Y10S623/921; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31551; Y10T428/31565
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
51 words
An implantable vessel prosthesis comprising a porous tubular structure sealed by impregnation with a material containing gelatin which is crosslinked with a diisocyanate so that pores of the structure are filled with an insoluble crosslinked gelatin/diisocyanate decomposable at a rate of tissue growth into the pores on implantation of the prosthesis.
Claim 2
Dependent Claim
51 words
An implantable vessel prosthesis comprising a porous tubular structure sealed by impregnation with a material containing gelatin which is crosslinked with a diisocyanate so that pores of the structure are filled with an insoluble crosslinked gelatin/diisocyanate decomposable at a rate of tissue growth into the pores on implantation of the prosthesis.
Claim 3
Dependent Claim
15 words
The vessel prosthesis defined in claim 1 wherein said tubular structure is a textile structure.
Claim 4
Dependent Claim
33 words
The vessel prosthesis defined in claim 1 wherein portions of the tubular structure bounding the pores are coated with a thin film of crosslinked gelatin and the pores are closed by gelatin membranes.
Claim 5
Dependent Claim
23 words
The vessel prosthesis defined in claim 1 wherein the weight ratio of the tubular structure to the impregnating material is 1:0.2 to 1:3.
Claim 6
Dependent Claim
15 words
The vessel prosthesis defined in claim 1 wherein the impregnating material contains a hydrophilic plasticizer.
Claim 7
Dependent Claim
20 words
The vessel prosthesis defined in claim 1 wherein the impregnating material contains 10 to 30 % by weight of water.
Claim 8
Dependent Claim
14 words
The vessel prosthesis defined in claim 1 wherein the diisocyanate is an aliphatic diisocyanate.
Claim 9
Dependent Claim
18 words
The vessel prosthesis defined in claim 1, wherein the impregnating material includes at least one therapeutically active material.
Claim 10
Dependent Claim
16 words
The vessel prosthesis defined in claim 8 wherein the impregnating material contains constituents with exchanger characteristics.
Claim 11
Dependent Claim
21 words
The vessel prosthesis according to claim 8 wherein the therapeutical active material is incorporated in a manner producing a delayed-release effect.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-11-15 | 1992-05-16 | 1992-11-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-11-15 | 1996-05-16 | 1996-11-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-11-15 | 2000-05-16 | 2000-11-15 | $7700.00 | Window Closed / Lapsed |