Patent US4772470A successfully refreshed from Google Patents.
US4772470A
Expired / Lapsed
US
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Oral bandage and oral preparations
Assignee: Sunstar Inc
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Filing: 1986-04-25
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Granted: 1988-09-20
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Expires: 2006-04-25
Abstract
Abstract An oral bandage comprising a soft adhesive film comprising a mixture of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state, and an oral preparation comprising such an oral bandage having incorporated therein a topical drug are disclosed. The oral bandage or preparation exhibits strong adhesion of long duration when applied to the oral mucosa or teeth.
Inventors
- 👤 Yuichi Inoue
- 👤 Tetuo Horiuchi
- 👤 Kenji Hsaegawa
- 👤 Koichi Nakashima
- 👤 Takashi Tsuyoshi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:07
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/006; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/225
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
64 words
An oral bandage comprising a soft adhesive film having a thickness of at least 5 μm consisting essentially of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state, wherein the polycarboxylic acid and/or the polycarboxylic acid anhydride and the vinyl acetate polymer are uniformly dissolved in each other without forming individual regions due to phase separation.
Claim 2
Dependent Claim
64 words
An oral bandage comprising a soft adhesive film having a thickness of at least 5 μm consisting essentially of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state, wherein the polycarboxylic acid and/or the polycarboxylic acid anhydride and the vinyl acetate polymer are uniformly dissolved in each other without forming individual regions due to phase separation.
Claim 3
Dependent Claim
40 words
An oral bandage as in claim 1, wherein a mixing ratio of the polycarboxylic acid and/or polycarboxylic acid anhydride to vinyl acetate polymer is such that the value as obtained from the following formula ranges from 15 to 45: ##EQU2##
Claim 4
Dependent Claim
36 words
An oral bandage as in claim 1, wherein said mixture in a compatible state is obtained by dissolving the polycarboxlyic acid and/or polycarboxylic acid anhydride and the vinyl acetate polymer in a solvent common to both.
Claim 5
Dependent Claim
17 words
An oral bandage as in claim 1, wherein said oral bandage further comprises a soft film support.
Claim 6
Dependent Claim
39 words
An oral bandage as in claim 1, wherein said adhesive film further comprises a basic substance capable of neutralizing the polycarboxylic acid and/or polycarboxylic acid anhydride in an amount which is effective to relieve irritation to an injured part.
Claim 7
Dependent Claim
19 words
An oral bandage as in claim 5, wherein said basic substance is at least one of salts and bases.
Claim 8
Dependent Claim
17 words
An oral bandage as in claim 5, wherein said oral bandage further comprises a soft film support.
Claim 9
Dependent Claim
36 words
An oral bandage as in claim 1, wherein said polycarboxylic acid contains 20% by weight or more of a --COOH group and said polycarboxylic acid anhydride contains 16% by weight or more of a --CO--O--CO-- group.
Claim 10
Dependent Claim
40 words
An oral bandage as in claim 6, whwerein said basic substance is a monovalent metal salt or monovalent base and is used in an amount of from 0.03 to 0.2 equivalent based on the polycarboxylic acid and/or polycarboxylic acid anhydride.
Claim 11
Dependent Claim
60 words
An oral bandage as in claim 3, wherein said solvent is selected from lower alcohols, mixed solvents comprising a lower alcohol in a larger proportion and a compatible organic solvent, mixed solvent of a lower alcohol in a larger proportion and water, and a mixed solvent comprising a lower alcohol in a larger proportion, a compatible organic solvent and water.
Claim 12
Dependent Claim
30 words
An oral bandage as in claim 10, wherein said mixed solvent of a lower alcohol and an organic solvent contains not more than 30% by weight of the organic solvent.
Claim 13
Dependent Claim
38 words
An oral bandage as in claim 10, wherein said mixed solvent of a lower alcohol and water or mixed solvent of a lower alcohol, an organic solvent and water contains not more than 30% by weight of water.
Claim 14
Dependent Claim
72 words
An oral preparation comprising a soft adhesive film having a thickness of at least 5 μm consisting essentially of a mixture of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state and topical drug incorporated therein, wherein the polycarboxylic acid and/or the polycarboxylic acid anhydride and the vinyl acetate polymer are uniformly dissolved in each other without forming individual regions due to phase separation.
Claim 15
Dependent Claim
72 words
An oral preparation comprising a soft adhesive film having a thickness of at least 5 μm consisting essentially of a mixture of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state and topical drug incorporated therein, wherein the polycarboxylic acid and/or the polycarboxylic acid anhydride and the vinyl acetate polymer are uniformly dissolved in each other without forming individual regions due to phase separation.
Claim 16
Dependent Claim
40 words
An oral preparation as in claim 13, wherein a mixing ratio of the polycarboxylic acid and/or polycarboxylic acid anhydride to vinyl acetate polymer is such that the value as obtained from the following formula ranges from 15 to 45: ##EQU3##
Claim 17
Dependent Claim
36 words
An oral preparation as in claim 13, wherein said mixture in a compatible state is obtained by dissolving the polycarboxylic acid and/or polycarboxylic acid anhydride and the vinyl acetate polymer in a solvent common to both.
Claim 18
Dependent Claim
39 words
An oral preparation as in claim 13, wherein said adhesive film further comprises a basic substance capable of neutralizing the polycarboxylic acid and/or polycarboxylic acid anhydride in an amount which is effective to relieve irritation to an injured part.
Claim 19
Dependent Claim
19 words
An oral preparation as in claim 16, wherein said basic substance is at least one of salts and bases.
Claim 20
Dependent Claim
17 words
An oral preparation as in claim 13, wherein said oral preparation further comprises a soft film support.
Claim 21
Dependent Claim
17 words
An oral preparation as in claim 16, wherein said oral preparation further comprises a soft film support.
Claim 22
Dependent Claim
15 words
An oral preparation as in claim 18, wherein the film support contains a topical drug.
Claim 23
Dependent Claim
15 words
An oral preparation as in claim 19, wherein the film support contains a topical drug.
Claim 24
Dependent Claim
36 words
An oral preparation as in claim 13, wherein said polycarboxylic acid contains 20% by weight or more of a --COOH group and said polycarboxylic acid anhydride contains 16% by weight or more of a --CO--O--CO-- group.
Claim 25
Dependent Claim
22 words
An oral bandage as in claim 13, wherein said vinyl acetate polymer has a viscosity-average molecular weight of not less than 60,000.
Claim 26
Dependent Claim
41 words
An oral bandage as in claim 17, wherein said basic substance is a monovalent metal salt or a monovalent base and is used in an amount of from 0.03 to 0.2 equivalent based on the polycarboxylic acid and/or polycarboxylic acid anhydride.
Claim 27
Dependent Claim
60 words
An oral bandage as in claim 15, wherein said sovlent is selected from lower alcohols, mixed solvents comprising a lower alcohol in a larger proportion and a compatible organic solvent, mixed solvent of a lower alcohol in a larger proportion and water, and a mixed solvent comprising a lower alcohol in a larger proportion, a compatible organic solvent and water.
Claim 28
Dependent Claim
30 words
An oral bandage as in claim 25, wherein said mixed solvent of a lower alcohol and an organic solvent contains not more than 30% by weight of the organic solvent.
Claim 29
Dependent Claim
38 words
An oral bandage as in claim 25, wherein said mixed solvent of a lower alcohol and water or mixed solvent of a lower alcohol, an organic solvent and water contains not more than 30% by weight of water.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-09-20 | 1992-03-21 | 1992-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-09-20 | 1996-03-21 | 1996-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-09-20 | 2000-03-21 | 2000-09-20 | $7700.00 | Window Closed / Lapsed |