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US4683288A Expired / Lapsed US ⏱️ 0.0 years remaining

Polymer and its production

Assignee: Takeda Pharmaceutical Co Ltd
•
Filing: 1985-07-03
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Granted: 1987-07-28
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Expires: 2005-07-03
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Abstract

Abstract A polymer or copolymer of lactic acid and/or glycolic acid which has a weight-average molecular weight of not less than about 5,000 and a dispersity of about 1.5 to 2 is advantageously used as a biodegradable polymer or copolymer for medical preparation.

Inventors

  • 👤 Motoaki Tanaka
  • 👤 Yasuaki Ogawa
  • 👤 Tsutomu Miyagawa
  • 👤 Toshio Watanabe

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 10:28
CPC Classifications
C; C08; C08G; C08G63/00; C08G63/02; C08G63/06; A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1641; A61K9/1647

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 70 words
In a method for producing a polymer or copolymer of lactic acid and/or glycolic acid by subjecting lactic acid and/or glycolic acid to a polycondensation reaction, an improvement which comprises employing a solid inorganic acid catalyst as a polycondensation catalyst, wherein the solid inorganic acid catalyst is one selected from the group consisting of acid clay, activated clay, bentonite, kaolin, talc, aluminum silicate, magnesium silicate, alumina bolia and silicic acid.
Claim 2
Dependent Claim 70 words
In a method for producing a polymer or copolymer of lactic acid and/or glycolic acid by subjecting lactic acid and/or glycolic acid to a polycondensation reaction, an improvement which comprises employing a solid inorganic acid catalyst as a polycondensation catalyst, wherein the solid inorganic acid catalyst is one selected from the group consisting of acid clay, activated clay, bentonite, kaolin, talc, aluminum silicate, magnesium silicate, alumina bolia and silicic acid.
Claim 3
Dependent Claim 33 words
A method as claimed in claim 1, wherein the weight-average molecular weight of the polymer or copolymer is about not less than 5,000 and a dispersity of it is about 1.5 to 2.
Claim 4
Dependent Claim 32 words
A method as claimed in claim 1, wherein the weight-average molecular weight of the polymer or copolymer is about 5,000 to 30,000 and a dispersity of it is about 1.5 to 2.
Claim 5
Dependent Claim 13 words
A method in claim 1, wherein the polymer consists of lactic acid unit.
Claim 6
Dependent Claim 18 words
A method as claimed in claim 1, wherein the copolymer consists of lactic acid and glycolic acid units.
Claim 7
Dependent Claim 31 words
A method as claimed in claim 5, wherein the copolymer ratio is about 50 to 95 weight % of lactic acid and about 50 to 5 weight % of glycolic acid.
Claim 8
Dependent Claim 31 words
A method as claimed in claim 5, wherein the copolymer ratio is about 60 to 95 weight % of lactic acid and about 40 to 5 weight % of glycolic acid.
Claim 9
Dependent Claim 31 words
A method as claimed in claim 5, wherein the copolymer ratio is about 60 to 85 weight % of lactic acid and about 40 to 15 weight % of glycolic acid.
Claim 10
Dependent Claim 27 words
A method as claimed in claim 5, wherein the copolymer ratio is about 75±2 mol % of lactic acid and about 25±2 mol % of glycolic acid.
Claim 11
Dependent Claim 30 words
A method as claimed in claim 1, wherein the solid inorganic acid catalyst is one selected from the group consisting of acid clay, activated clay, kaolin, bentonite and aluminium silicate.
Claim 12
Dependent Claim 16 words
A method as claimed in claim 1, wherein the solid inorganic acid catalyst is acid clay.
Claim 13
Dependent Claim 16 words
A method as claimed in claim 1, wherein the solid inorganic acid catalyst is activated clay.
Claim 14
Dependent Claim 16 words
A method as claimed in claim 1, wherein the solid inorganic acid catalyst is aluminium silicate.

References Cited (Backward Citations)

US2362511A Cited
US2703316A Cited
US3531561A Cited
US3468853A Cited
US3636956A Cited
US3839297A Cited
US4137921A Cited
US4273920A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-07-27 1991-01-26 1991-07-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-07-27 1995-01-26 1995-07-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-07-27 1999-01-26 1999-07-28 $7700.00 Window Closed / Lapsed

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