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US4680956A Expired / Lapsed US ⏱️ 0.0 years remaining

Respiratory analyzer calibration apparatus with controlled respiratory gas exchange simulation

Assignee: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
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Filing: 1986-03-24
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Granted: 1987-07-21
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Expires: 2006-03-24
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Abstract

Abstract A method and apparatus for the controlled simulation of respiratory gas exchange as it takes place in mammals, for the primary purpose of calibrating and checking the performance of laboratory and clinical test equipment systems. The method and apparatus can reproduce any range of respiratory performance by pumping and mixing atmospheric air with a gas mixture of carbon dioxide and nitrogen. The subject matter of the disclosure provides an accurate, economical and rapid means of on-line calibration of analytical respiratory test systems.

Inventors

  • 👤 Andrew R. Huszczuk

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 02:38
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/497; G01N33/0004; G01N33/0006

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 272 words
Apparatus for simulating the respiratory cycle of a biological subject which comprises: a piston chamber; a piston slidably movable within said piston chamber; power means for moving said piston within said piston chamber in a reciprocal forward and backward cycle of movement, each complete cycle of movement of said piston corresponding to an inhalation phase and an exhalation phase of a single respiratory cycle; a first container means adapted to contain calibration gas; a first conduit means; a first valve means for introducing, via said first conduit means, a known volume of said calibration gas to said piston chamber from said first container means during said inhalation phase of each of said cycle of piston movement; a second conduit means; a second valve means for introducing, via said second conduit means, a known volume of air to said piston chamber for admixture with said calibration gas, in said piston chamber during said inhalation phase of each said cycle of piston movement, both said calibration gas and air introduced into said piston chamber during said inhalation phase, simulating inhalation and a given metabolic rate; a third valve means for expelling said admixed air and calibration gases from said piston chamber during said exhalation phase of said cycle of piston movement, said expelling of said gases simulating exhalation and a predetermined metabolic rate; and a third conduit means for communicating said expelled gases, resulting from a series of complete cycles of movement of said piston, into a respiratory analysis system for calibration and adjustment of said respiratory analysis system with reference to the known compositions and volumes of gas expelled from said piston chamber.
Claim 2
Dependent Claim 272 words
Apparatus for simulating the respiratory cycle of a biological subject which comprises: a piston chamber; a piston slidably movable within said piston chamber; power means for moving said piston within said piston chamber in a reciprocal forward and backward cycle of movement, each complete cycle of movement of said piston corresponding to an inhalation phase and an exhalation phase of a single respiratory cycle; a first container means adapted to contain calibration gas; a first conduit means; a first valve means for introducing, via said first conduit means, a known volume of said calibration gas to said piston chamber from said first container means during said inhalation phase of each of said cycle of piston movement; a second conduit means; a second valve means for introducing, via said second conduit means, a known volume of air to said piston chamber for admixture with said calibration gas, in said piston chamber during said inhalation phase of each said cycle of piston movement, both said calibration gas and air introduced into said piston chamber during said inhalation phase, simulating inhalation and a given metabolic rate; a third valve means for expelling said admixed air and calibration gases from said piston chamber during said exhalation phase of said cycle of piston movement, said expelling of said gases simulating exhalation and a predetermined metabolic rate; and a third conduit means for communicating said expelled gases, resulting from a series of complete cycles of movement of said piston, into a respiratory analysis system for calibration and adjustment of said respiratory analysis system with reference to the known compositions and volumes of gas expelled from said piston chamber.
Claim 3
Dependent Claim 19 words
The apparatus of claim 1 which includes only a single piston chamber, and a single piston slidably moveable therewithin.
Claim 4
Dependent Claim 17 words
The apparatus of claim 1 wherein said first container means is a flexibly-walled collapsible bladder or bellows.
Claim 5
Dependent Claim 31 words
The apparatus of claim 1 wherein said first container means is provided with a flow communication means adapted to communicate with a tank means containing said calibration gas, in bulk form.
Claim 6
Dependent Claim 21 words
The apparatus of claim 1 in which said piston is variable in frequency and extent of movement within said piston chamber.
Claim 7
Dependent Claim 17 words
The apparatus of claim 1 wherein said first, second and third valve means are one-way pressure valves.
Claim 8
Dependent Claim 33 words
The apparatus of claim 1 in which said second valve means automatically opens after said known volume of said calibration gas has been evacuated from said bladder and introduced into said position chamber.
Claim 9
Dependent Claim 26 words
The apparatus of claim 1 in which said second valve means opens as said known volume of said calibration gas is introduced into said piston chamber.
Claim 10
Dependent Claim 16 words
The apparatus of claim 1 wherein said second and third conduit means include elongated corrugated tubing.
Claim 11
Dependent Claim 28 words
The apparatus of claim 1 wherein said first valve means opens in response to the suction created in the piston chamber during the respiratory phase of each cycle.
Claim 12
Dependent Claim 38 words
The apparatus of claim 1 wherein said second valve means is pressure-responsive to open when said calibration gas pressure is below a pre-determined pressure level corresponding to a substantially evacuated volume of calibration gas in said first container.

References Cited (Backward Citations)

US3943775A Cited
US4509359A Cited
US4448058A Cited
US4537058A Cited
US4516424A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-07-20 1991-01-19 1991-07-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-07-20 1995-01-19 1995-07-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-07-20 1999-01-19 1999-07-21 $7700.00 Window Closed / Lapsed

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