Patent US4647857A successfully refreshed from Google Patents.
US4647857A
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Flow measurement using nuclear magnetic resonance
Assignee: Leland Stanford Junior University
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Filing: 1984-10-22
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Granted: 1987-03-03
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Expires: 2004-10-22
Abstract
Abstract A modified spin echo sequence is employed to identify fluid movement in a material. The volume of interest is subjected to a static field along one axis (Z) and an RF magnetic excitation pulse transverse to the static field is applied which tilts the nuclear spins in the volume. The tilted nuclear spins are then allowed to precess about the uniform static field in the presence of a gradient field whereby the nuclear spins become dephased. Thereafter, a spin echo of the static spins is created by either a 180° RF pulse or reversal of the gradient field. Upon refocusing of the static nuclear spins a restoration RF pulse is applied to realign the stationary nuclear spins with the static field. Nuclear spins undergoing bulk motion as in fluid flow will be refocused to a different phase than the stationary spins so that the final RF pulse will in general leave these spins with a non-zero transverse magnetic moment. This residual transverse magnetic moment is then detected to identify the fluid movement.
Inventors
- 👤 Michael A. Taber
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:49
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/563; G01R33/56308; G01R33/56316
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
87 words
A method of identifying fluid movement in a material comprising the steps of applying a static magnetic field to said material thereby aligning nuclear spins, applying a first RF magnetic pulse to said material thereby tilting said nuclear spins, applying a gradient field to said nuclei whereby said nuclear spins become dephased, refocusing said dephased nuclear spins, applying a restoration RF magnetic pulse to said nuclear spins upon refocusing of said nuclear spins, and identifying residual transverse nuclear moments in said material as indicative of moving nuclei.
Claim 2
Independent Claim
87 words
A method of identifying fluid movement in a material comprising the steps of applying a static magnetic field to said material thereby aligning nuclear spins, applying a first RF magnetic pulse to said material thereby tilting said nuclear spins, applying a gradient field to said nuclei whereby said nuclear spins become dephased, refocusing said dephased nuclear spins, applying a restoration RF magnetic pulse to said nuclear spins upon refocusing of said nuclear spins, and identifying residual transverse nuclear moments in said material as indicative of moving nuclei.
Claim 3
Dependent Claim
49 words
The method as defined by claim 1 wherein said nuclei are selectively excited in a planar slice by means of further including the step of superimposing a gradient magnetic field on said static magnetic field, said first RF magnetic pulse being at the Larmor frequency for said planar slice.
Claim 4
Dependent Claim
24 words
The method as defined by claim 2 wherein said step of identifying residual nuclei spin includes detecting FID signals from said residual nuclear spins.
Claim 5
Dependent Claim
37 words
The method as defined by claim 3 and further including the step of selectively applying a gradient magnetic field to said residual nuclei spins during the detecting of FID signals to determine the location of nuclear movement.
Claim 6
Dependent Claim
18 words
The method as defined by claim 4 and further including the step of imaging said residual magnetic spins.
Claim 7
Dependent Claim
24 words
The method as defined by claim 1, wherein said step of identifying residual nuclear spins includes detecting FID signals from said residual nuclear spins.
Claim 8
Dependent Claim
18 words
The method as defined by claim 6 and further including the step of imaging said residual magnetic spins.
Claim 9
Dependent Claim
16 words
The method as defined by claim 1 wherein fluid movement is blood flow in a body.
Claim 10
Dependent Claim
98 words
Apparatus for identifying fluid movement in a material comprising means for applying a static magnetic field to said material, means for applying an RF magnetic pulse to said material thereby tilting nuclei spins in said material, means for applying a gradient field to said nuclei whereby said nuclear spins become dephased, means for refocusing said dephased nuclear spins to produce a spin echo, means for applying a restoration RF magnetic pulse to said nuclei spins upon refocusing of said nuclei spins of static nuclear, and means for identifying residual nuclear spins in said material indicative of moving nuclei.
Claim 11
Dependent Claim
98 words
Apparatus for identifying fluid movement in a material comprising means for applying a static magnetic field to said material, means for applying an RF magnetic pulse to said material thereby tilting nuclei spins in said material, means for applying a gradient field to said nuclei whereby said nuclear spins become dephased, means for refocusing said dephased nuclear spins to produce a spin echo, means for applying a restoration RF magnetic pulse to said nuclei spins upon refocusing of said nuclei spins of static nuclear, and means for identifying residual nuclear spins in said material indicative of moving nuclei.
Claim 12
Dependent Claim
40 words
Apparatus as defined by claim 9 wherein said nuclei are in a plane and further including means for superimposing a gradient magnetic field on said static magnetic field, said RF magnetic pulse being at the Larmor frequency for said plane.
Claim 13
Dependent Claim
25 words
Apparatus as defined by claim 10 wherein said means for identifying residual nuclei spins includes means for detecting FID signals from said residual nuclei spins.
Claim 14
Dependent Claim
32 words
Apparatus as defined by claim 11 and further including means for selectively applying a gradient field to said residual nuclei spins during the detecting of FID signals to thereby determine nuclear movement.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-03-02 | 1990-09-01 | 1991-03-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-03-02 | 1994-09-01 | 1995-03-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-03-02 | 1998-09-01 | 1999-03-03 | $7700.00 | Window Closed / Lapsed |