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US4606910A Expired / Lapsed US ⏱️ 0.0 years remaining

Composite hemostatic article including a hemostatic agent onlay and methods for preparing the same

Assignee: SUPERSTAT Corp
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Filing: 1984-06-28
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Granted: 1986-08-19
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Expires: 2004-06-28
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Abstract

Abstract An improved hemostatic article is made by fusing an onlay of hemostatic agent to a porous body which is already impregnated with the same or with a different hemostatic agent. The hemostatic agent(s) may comprise a collagen or collagen-like substance which has been modified by rendering the surface charge thereof effectively more positive than prior to modification.

Inventors

  • 👤 Philip N. Sawyer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 08:02
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/425; A61F; A61F13/00; A61F13/00051; A61F13/00063; A61F13/01; A61F13/01034; A61L15/22; A61L15/32; A61L15/325; A61F13/15; A61F13/84; A61F13/8405; A61F2013/00361; A61F2013/00365; A61F2013/00463; A61F2013/00472; A61F2013/00902; A61F2013/00927; A61F13/15577; A61F2013/15821; A61F13/53; A61F13/534; A61F2013/53445; A61L2400/00; A61L2400/04; Y; Y10; Y10S; Y10S128/00; Y10S128/08

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 66 words
A method comprising incorporating a first hemostatic agent into a porous body to form a hemostatic material, preparing a second hemostatic agent with at least a portion thereof in liquid phase, affixing an onlay of said second hemostatic agent to said material by freezing the liquid portion of said second hemostatic agent to said material whereby to form an onlaid hemostatic article, and drying said article.
Claim 2
Independent Claim 66 words
A method comprising incorporating a first hemostatic agent into a porous body to form a hemostatic material, preparing a second hemostatic agent with at least a portion thereof in liquid phase, affixing an onlay of said second hemostatic agent to said material by freezing the liquid portion of said second hemostatic agent to said material whereby to form an onlaid hemostatic article, and drying said article.
Claim 3
Dependent Claim 21 words
A method as claimed in claim 1 wherein the first and second hemostatic agents are of substantially the same chemical composition.
Claim 4
Dependent Claim 63 words
A method as claimed in claim 2 wherein the first and second hemostatic agents are prepared by modifying one of the group consisting of a collagen or a collagen-like substance by dissolving the substance in water and modifying the thusly dissolved substance to render the surface charge thereof effectively more positive than prior to modification while retaining the water solubility of the substance.
Claim 5
Dependent Claim 26 words
A method as claimed in claim 3 wherein the second hemostatic agent is incorporated into said porous body in liquid phase and is subsequently frozen thereinto.
Claim 6
Dependent Claim 18 words
A method as claimed in claim 4 wherein the porous body is saturated with said first hemostatic agent.
Claim 7
Dependent Claim 27 words
A method as claimed in claim 3 wherein the hemostatic material is prepared by freeze drying or vacuum drying the first hemostatic agent in said porous body.
Claim 8
Dependent Claim 43 words
A method as claimed in claim 3 wherein the second hemostatic agent is prepared with at least a portion thereof in liquid phase by first freezing said second hemostatic agent and then melting at least the surface of the thusly frozen second agent
Claim 9
Dependent Claim 78 words
A method as claimed in claim 1 wherein the onlay of said second hemostatic agent is affixed to said material by rotating a wheel applicator through a vessel containing said second agent and past said material respectively so that a quantity of said second agent is deposited first on said wheel applicator and subsequently on said material with at least a portion thereof in liquid phase, and freezing the liquid portion of said second agent to said material.
Claim 10
Dependent Claim 33 words
A method as claimed in claim 8 wherein the liquid portion of said second agent is frozen to said material by passing said material with said second agent deposited thereon into a freezer.
Claim 11
Dependent Claim 22 words
A method as claimed in claim 1 wherein the onlay of said second hemostatic agent is affixed to said material by spraying.
Claim 12
Dependent Claim 16 words
A method as claimed in claim 1 wherein said article is dried to remove water therefrom.
Claim 13
Independent Claim 45 words
A method for preparing a hemostatic article which comprises: incorporating a first hemostatic material into a porous body; and affixing a layer or coating of a second hemostatic material upon at least a portion of one surface of said porous body and first hemostatic material.
Claim 14
Independent Claim 45 words
A method for preparing a hemostatic article which comprises: incorporating a first hemostatic material into a porous body; and affixing a layer or coating of a second hemostatic material upon at least a portion of one surface of said porous body and first hemostatic material.
Claim 15
Dependent Claim 66 words
The method of claim 12 wherein the step of affixing a layer or coating of a second hemostatic material comprises applying to said porous body, said second hemostatic material, at least a portion of which is in liquid phase, and drying said liquid phase portion to affix said layer or coating of said second hemostatic agent upon said portion of one surface of said porous body.
Claim 16
Dependent Claim 16 words
A hemostatic article prepared in accordance with one of claims 12, 3, 4, 6 or 5.
Claim 17
Dependent Claim 39 words
A hemostatic article comprising: a porous body; a first hemostatic agent incorporated into said porous body; and a layer or coating of a second hemostatic agent affixed to at least a portion of one surface of said porous body.
Claim 18
Dependent Claim 39 words
A hemostatic article comprising: a porous body; a first hemostatic agent incorporated into said porous body; and a layer or coating of a second hemostatic agent affixed to at least a portion of one surface of said porous body.
Claim 19
Dependent Claim 20 words
The hemostatic article of claim 15 wherein said second hemostatic agent substantially covers said one surface of said porous body.
Claim 20
Dependent Claim 24 words
The hemostatic article of claim 15 wherein at least one of said first and second hemostatic agents is a modified collagen or collagen-like substance.
Claim 21
Dependent Claim 25 words
The hemostatic article of claim 15 wherein said porous body is a bandage, gauze, pad, strip or sponge, each of a natural or synthetic material.

References Cited (Backward Citations)

US4233360A Cited
US4022203A Cited
US4238480A Cited
US4390519A Cited
US4404970A Cited
US4407787A Cited
US4453939A Cited
US4424208A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-08-18 1990-02-17 1990-08-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-08-18 1994-02-17 1994-08-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-08-18 1998-02-17 1998-08-19 $7700.00 Window Closed / Lapsed

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