US4597766A
Expired / Lapsed
US
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Implantable bioprosthetic tendons and ligaments
Assignee: Baxter International Inc
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Filing: 1984-10-26
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Granted: 1986-07-01
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Expires: 2004-10-26
Abstract
Abstract A tendon or ligament bioprosthesis comprised of a naturally occurring tendon or ligament isolated from an animal source, tanned with a bifunctional reagent capable of cross-linking biological tissue, at least one end of the tendon or ligament having attached thereto an intact decalcified chip of the bone from which the tendon or ligament was isolated. The presence of the decalcified bone chip provides a substrate which is receptive to the ingrowth of bone tissue when the bioprosthesis is implanted in a resected bone.
Inventors
- 👤 Said S. Hilal
- 👤 Aws Nashef
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 04:27
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3641; A61L27/3645; A61L27/3662; A61F; A61F2/00; A61F2/02; A61F2/08; A61K; A61K35/00; A61K35/12; A61K35/32; A61L27/3683; A61L27/3687; A61L2430/00; A61L2430/10
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
91 words
A tendon or ligament bioprosthesis comprised of a naturally occurring tendon or ligament isolated from an animal source, tanned with a bifunctional reagent capable of cross-linking biological tissue, at least one end of the tendon or ligament having attached thereto an intact pliable decalcified chip of the bone from which the tendon or ligament was isolated wherein said bioprosthesis is threaded through a channel of resected bone and said chip being shaped to be received and retained in a recessed opening of said bone thereby affixing said bioprosthesis within said channel.
Claim 2
Dependent Claim
91 words
A tendon or ligament bioprosthesis comprised of a naturally occurring tendon or ligament isolated from an animal source, tanned with a bifunctional reagent capable of cross-linking biological tissue, at least one end of the tendon or ligament having attached thereto an intact pliable decalcified chip of the bone from which the tendon or ligament was isolated wherein said bioprosthesis is threaded through a channel of resected bone and said chip being shaped to be received and retained in a recessed opening of said bone thereby affixing said bioprosthesis within said channel.
Claim 3
Dependent Claim
14 words
The bioprosthesis of claim 1 wherein the tendon or ligament is tanned with gluteraldehyde.
Claim 4
Dependent Claim
26 words
The bioprosthesis of claim 2 wherein the tendon or ligament is tanned with a solution containing about 0.2 to about 0.8 weight percent of said glutaraldehyde.
Claim 5
Independent Claim
111 words
A method of implanting a tendon or ligament bioprosthesis in a bone to effect an anchoring of the bioprosthesis on the bone which comprises isolating from an animal bone a tendon or ligament intact with a chip of the bone from which it was isolated, tanning the ligament or tendon with a bifunctional reagent capable of cross-linking biological tissue, decalcifying the chip to place the chip in a pliable state and threading the tanned ligament or tendon with the intact, decalcified, pliable bone chip through a channel of resected bone having internal dimensions sufficient to allow threading of the ligament or tendon therethrough and to receive and retain the bone chip.
Claim 6
Independent Claim
111 words
A method of implanting a tendon or ligament bioprosthesis in a bone to effect an anchoring of the bioprosthesis on the bone which comprises isolating from an animal bone a tendon or ligament intact with a chip of the bone from which it was isolated, tanning the ligament or tendon with a bifunctional reagent capable of cross-linking biological tissue, decalcifying the chip to place the chip in a pliable state and threading the tanned ligament or tendon with the intact, decalcified, pliable bone chip through a channel of resected bone having internal dimensions sufficient to allow threading of the ligament or tendon therethrough and to receive and retain the bone chip.
Claim 7
Dependent Claim
25 words
The method of claim 4 wherein the tendon or ligament is tanned with a bifunctional reagent comprised of solution containing about 0.2 to about 0.8.
Claim 8
Dependent Claim
22 words
The method of claim 4 wherein the bone chip is shaped to be nested in a recessed opening of the resected bone.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-06-30 | 1989-12-30 | 1990-07-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-06-30 | 1993-12-30 | 1994-07-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-06-30 | 1997-12-30 | 1998-07-01 | $7700.00 | Window Closed / Lapsed |