Patent US4563170A successfully refreshed from Google Patents.
US4563170A
Expired / Lapsed
US
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Device for in vivo purification of blood
Assignee: Individual
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Filing: 1983-07-29
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Granted: 1986-01-07
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Expires: 2003-07-29
Abstract
Abstract Device for in-vivo purification of the blood, with which blood pumped from a vein is subjected to intensive ultrafiltration and the filtrate, together with a quantity of the substitution fluid volumetrically corresponding to the filtrate, is returned to the vein, which device combines a double lumen catheter, an inserted, initial tube pump, and an ultrafiltration filter, with connecting tubes between catheter and pump. A feed line, with an inserted, second pump for the substitute fluid, opens into the return line from the hemofilter to the catheter, and a feed line for anticoagulants opens into the feed line to the first tube pump; the ultrafilatration filter is also connected through a precisely adjustable valve to a measuring container in which the fluid drawn out of the system is collected. The device is particularly suited for the filtration of venous blood in intraaterial chemotherapy, the chemotherapeutic agents, particularly cytostatic drugs, being filtered out before they reach the heart, so that toxic secondary effects do not arise.
Inventors
- 👤 Karl Aigner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:51
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/158; A61M5/1582; A61M1/00; A61M1/14; A61M1/16; A61M1/34; A61M1/3403; A61M1/341; A61M1/36; A61M1/3615; A61M1/3621; A61M1/3623; A61M25/00; A61M25/0021; A61M25/0023; A61M25/0026; A61M25/003; A61M2025/0031; A61M2205/00; A61M2205/33; A61M2205/3331; A61M25/0032
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
244 words
An in-vivo blood purification system for use in intra-arterial chemotherapy, said system comprising: a substantially cylindrical double-lumen catheter insertable into the vena cava up to the vicinity of the heart and being formed to provide therein a first channel (B) and, generally parallel thereto, a second channel (A), each said channel being at least partially bounded by the wall of said catheter, and the catheter having a closed tip and a plurality of openings (11) which are laterally positioned in the vicinity of the catheter tip and communicate with said first channel (B), and said second channel (A) terminating with at least two openings (12) in said wall of the catheter, the distance between the lateral opening (11) farthest from the catheter tip and the closest opening (12) of the second channel (A) being not less than 40 mm and not more than 50 mm, and the opening (12) at the end of the second channel (A) having the same size as the inner cross-sectional area of said channel (A); means (8, etc.) connected to said second channel (A) for pumping large amounts of blood out of the vena cava through said channel; means (1, etc.) for sujecting said blood to ultrafiltration; and means (9, etc.) connected to said first channel (B) for returning, simultaneously with the withdrawal of blood from said second channel (A), the filtrate to the vena cava through said first channel (B) together with a requisite amount of substitute fluid.
Claim 2
Dependent Claim
244 words
An in-vivo blood purification system for use in intra-arterial chemotherapy, said system comprising: a substantially cylindrical double-lumen catheter insertable into the vena cava up to the vicinity of the heart and being formed to provide therein a first channel (B) and, generally parallel thereto, a second channel (A), each said channel being at least partially bounded by the wall of said catheter, and the catheter having a closed tip and a plurality of openings (11) which are laterally positioned in the vicinity of the catheter tip and communicate with said first channel (B), and said second channel (A) terminating with at least two openings (12) in said wall of the catheter, the distance between the lateral opening (11) farthest from the catheter tip and the closest opening (12) of the second channel (A) being not less than 40 mm and not more than 50 mm, and the opening (12) at the end of the second channel (A) having the same size as the inner cross-sectional area of said channel (A); means (8, etc.) connected to said second channel (A) for pumping large amounts of blood out of the vena cava through said channel; means (1, etc.) for sujecting said blood to ultrafiltration; and means (9, etc.) connected to said first channel (B) for returning, simultaneously with the withdrawal of blood from said second channel (A), the filtrate to the vena cava through said first channel (B) together with a requisite amount of substitute fluid.
Claim 3
Dependent Claim
25 words
A system as claimed in claim 1, wherein the ratio of the cross-sectional areas of the first and second channels is from 1:1 to 2:1.
Claim 4
Dependent Claim
30 words
A system as claimed in claim 1, wherein the openings (12) at the end of the second channel (A) are as large as the cross-section of the second channel (A).
Claim 5
Dependent Claim
34 words
A system as claimed in claim 1, wherein a bulge (13) about 2 mm thick extends over half of the outer circumference of the catheter 10 between the openings (12) in the catheter wall.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-01-06 | 1989-07-08 | 1990-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-01-06 | 1993-07-08 | 1994-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-01-06 | 1997-07-08 | 1998-01-07 | $7700.00 | Window Closed / Lapsed |