US4552552A — Pump system for use with dialysis and like appara…

Claim 1

Independent Claim 247 words

A system for cleaning the blood of a patient by clearing products of metabolism from the patient's blood comprising: a dialyser; means connected to the dialyser for forming a dialysate circuit; means connected to the dialyser for forming a blood circuit including a blood intake, a blood outlet and means for connecting the blood intake and blood outlet to the patient's blood stream; means for pumping the blood through the blood circuit including a rigid casing and a flexible diaphragm within the casing, the diaphragm defining and separating a working chamber and a blood chamber which is expandable and contractable for pumping blood; means including a displaceable chamber for supplying the working chamber with a working fluid for expanding and contracting the working chamber so that the blood chamber is contracted and expanded; low pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure below a predetermined low pressure in the working chamber by venting the working chamber, and high pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure above a predetermined high pressure in the working chamber by venting the working chamber, whereby the supplying means and the blood pumping means operate in phase at pressures between the predetermined low and high pressures within completion of one cycle of expansion and contraction after start up regardless of the phase differences at start up.

Claim 2

Independent Claim 247 words

A system for cleaning the blood of a patient by clearing products of metabolism from the patient's blood comprising: a dialyser; means connected to the dialyser for forming a dialysate circuit; means connected to the dialyser for forming a blood circuit including a blood intake, a blood outlet and means for connecting the blood intake and blood outlet to the patient's blood stream; means for pumping the blood through the blood circuit including a rigid casing and a flexible diaphragm within the casing, the diaphragm defining and separating a working chamber and a blood chamber which is expandable and contractable for pumping blood; means including a displaceable chamber for supplying the working chamber with a working fluid for expanding and contracting the working chamber so that the blood chamber is contracted and expanded; low pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure below a predetermined low pressure in the working chamber by venting the working chamber, and high pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure above a predetermined high pressure in the working chamber by venting the working chamber, whereby the supplying means and the blood pumping means operate in phase at pressures between the predetermined low and high pressures within completion of one cycle of expansion and contraction after start up regardless of the phase differences at start up.

Claim 3

Dependent Claim 34 words

The system as claimed in claim 1 wherein the displaceable chamber has a displacement greater than the volume able to be taken up by the working chamber in the means for pumping the blood.

Claim 4

Dependent Claim 19 words

The system as claimed in claim 2 wherein said displacement is up to 20% greater than the said volume.

Claim 5

Dependent Claim 47 words

The system as claimed in claim 1 wherein said diaphragm is in the form of a flexible tube, said casing being in the form of a hollow cylinder with end plates at ends thereof, said flexible tube being fixed into position at and between said end plates.

Claim 6

Dependent Claim 32 words

The system as claimed in claim 4 wherein said hollow cylinder has at least one port for forming a fluid connection and having a line joining said port with said supplying means.

Claim 7

Dependent Claim 69 words

The system as claimed in claim 4 wherein said casing includes an inner casing wall and a concentric outer casing wall, the tube being within the inner casing wall, a ring-like space being between the flexible tube and the inner casing wall, a further ring-like space between said inner casing wall and the outer casing wall, the two said ring-like spaces being in fluid communication with the supplying means.

Claim 8

Dependent Claim 31 words

The system as claimed in claim 5 wherein said line hollow cylinder and said supplying means has a hydrophobic diaphragm within it that covers the inner cross section of said line.

Claim 9

Dependent Claim 22 words

The system as claimed in claim 4 wherein said flexible tube is capable of undergoing at least five-fold expansion of its volume.

Claim 10

Dependent Claim 31 words

The system as claimed in claim 4 wherein said flexible tube is composed of a material selected from the group comprising: a polyurethane, unvulcanized rubber, silicone rubber, vulcanized rubber, regenerated rubber.

Claim 11

Dependent Claim 25 words

The system as claimed in claim 4 wherein the said tube has a wall becoming thinner from one end of the tube to the other.

Claim 12

Dependent Claim 67 words

The system as claimed in claim 1 further comprising a plurality of clamp means for selectively limiting flow at predetermined points in the blood circuit means, means for positively driving said supplying means between maximum and minimum volumes positions and means for clamping at least one and unclamping at least another of said plurality of clamping means at maximum and minimum volumes positions of said supplying means.

Claim 13

Dependent Claim 26 words

The system as claimed in claim 1 further comprising monitoring means for limiting the pressure and controlling the rate of fluid provided by the supplying means.

Claim 14

Dependent Claim 38 words

The system as claimed in claim 1 further comprising monitoring means for monitoring the timing and phase relationship of the low and high pressure limiting valve means and giving an alarm signal upon malfunction of said valve means.

Claim 15

Dependent Claim 47 words

The system as claimed in claim 1 further comprising a fluid line joined to the supplying means, a pressure pick up responsive to the pressure in said line, and a monitoring means for detecting, together with the pick up, a deviation in a train of pressure changes.

Claim 16

Dependent Claim 199 words

A pumping system for pumping the blood of a patient comprising: a rigid casing and a flexible diaphragm within the casing, the diaphragm defining and separating a working chamber and a blood chamber which is expandable and contractable for pumping blood said blood chamber having blood inlet means and blood outlet means in fluid communication therewith; means including a displaceable chamber for supplying the working chamber with a working fluid for expanding and contracting the working chamber so that the blood chamber is contracted and expanded; low pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure below a predetermined low pressure in the working chamber by venting the working chamber, and high pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure above a predetermined high pressure in the working chamber by venting the working chamber, whereby the supplying means and the blood pumping means operate in phase at pressures between the predetermined low and high pressures within completion of one cycle of expansion and contraction after start up regardless of phase differences at start up.

Claim 17

Dependent Claim 199 words

A pumping system for pumping the blood of a patient comprising: a rigid casing and a flexible diaphragm within the casing, the diaphragm defining and separating a working chamber and a blood chamber which is expandable and contractable for pumping blood said blood chamber having blood inlet means and blood outlet means in fluid communication therewith; means including a displaceable chamber for supplying the working chamber with a working fluid for expanding and contracting the working chamber so that the blood chamber is contracted and expanded; low pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure below a predetermined low pressure in the working chamber by venting the working chamber, and high pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure above a predetermined high pressure in the working chamber by venting the working chamber, whereby the supplying means and the blood pumping means operate in phase at pressures between the predetermined low and high pressures within completion of one cycle of expansion and contraction after start up regardless of phase differences at start up.

Claim 18

Dependent Claim 204 words

A pumping system for pumping the blood of a patient comprising: a rigid casing and a flexible diaphragm within the casing, the diaphragm defining and separating a working chamber and a blood chamber which is expandable and contractable for pumping blood said blood chamber having blood inlet means and blood outlet means in fluid communication therewith; means for alternately creating a pressure above ambient pressure and a pressure below ambient pressure in the working chamber so that the blood chamber is alternately contracted and expanded; low pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure below a predetermined low pressure in the working chamber by venting the working chamber to the ambient, and high pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure above a predetermined high pressure in the working chamber by venting the working chamber to the ambient, whereby the supplying means and the blood pumping means operate in phase at pressures between the predetermined low and high pressures within completion of one cycle of expansion and contraction after start up regardless of phase differences at start up.

Claim 19

Dependent Claim 204 words

A pumping system for pumping the blood of a patient comprising: a rigid casing and a flexible diaphragm within the casing, the diaphragm defining and separating a working chamber and a blood chamber which is expandable and contractable for pumping blood said blood chamber having blood inlet means and blood outlet means in fluid communication therewith; means for alternately creating a pressure above ambient pressure and a pressure below ambient pressure in the working chamber so that the blood chamber is alternately contracted and expanded; low pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure below a predetermined low pressure in the working chamber by venting the working chamber to the ambient, and high pressure limiting valve means in fluid communication with the working chamber responsive to pressure within the working chamber for preventing pressure above a predetermined high pressure in the working chamber by venting the working chamber to the ambient, whereby the supplying means and the blood pumping means operate in phase at pressures between the predetermined low and high pressures within completion of one cycle of expansion and contraction after start up regardless of phase differences at start up.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1988-11-11	1989-05-13	1989-11-12	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1992-11-11	1993-05-13	1993-11-12	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	1996-11-11	1997-05-13	1997-11-12	$7700.00	Window Closed / Lapsed

Pump system for use with dialysis and like apparatus

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