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US4540568A Expired / Lapsed US ⏱️ 0.0 years remaining

Injectionable viscoelastic ophthalmic gel

Assignee: Individual
•
Filing: 1984-06-27
•
Granted: 1985-09-10
•
Expires: 2004-06-27
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Abstract

Abstract An improved injectionable viscoelastic gel for use in opthalmic surgical and treatment procedures, wherein the gelling agent is a high molecular weight polyacrylamide or polymethacrylamide.

Inventors

  • 👤 Seymour F. Trager
  • 👤 Victoria S. Chylinski

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 06:42
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/30; A61K47/32; A61K31/00; A61K31/74; A61K31/785; A61K9/00; A61K9/0012; A61K9/0048; A61L; A61L27/00; A61L27/14; A61L27/16; A61L27/50; A61L27/52; A61L2400/00; A61L2400/06; A61L2430/00; A61L2430/16

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 120 words
An injectionable viscoelastic gel particularly adapted for use in ophthalmic surgical procedures and treatments which gel consisting essentially of from about 2 to about 5 percent by weight of a polymer selected from polyacrylamide and polymethacrylamide, said polymer having a molecular weight of from about 1 to about 6 million; from about 0.4 to about 8.6 percent by weight sodium chloride, from about 0.075 to about 0.3 percent by weight postassium chloride, from about 0.04 to about 0.33 percent by weight calcium chloride, from about 0.02 to about 0.04 percent by weight magnesium chloride hexahydrate, from about 0.3 to about 0.4 percent by weight sodium acetate, from about 0.15 to about 0.20 percent by weight of a buffer, remainder water.
Claim 2
Dependent Claim 120 words
An injectionable viscoelastic gel particularly adapted for use in ophthalmic surgical procedures and treatments which gel consisting essentially of from about 2 to about 5 percent by weight of a polymer selected from polyacrylamide and polymethacrylamide, said polymer having a molecular weight of from about 1 to about 6 million; from about 0.4 to about 8.6 percent by weight sodium chloride, from about 0.075 to about 0.3 percent by weight postassium chloride, from about 0.04 to about 0.33 percent by weight calcium chloride, from about 0.02 to about 0.04 percent by weight magnesium chloride hexahydrate, from about 0.3 to about 0.4 percent by weight sodium acetate, from about 0.15 to about 0.20 percent by weight of a buffer, remainder water.
Claim 3
Dependent Claim 12 words
A gel as defined in claim 1 wherein said polymer is polyacrylamide.
Claim 4
Dependent Claim 25 words
A gel as defined in claim 1 wherein said polymer is present in an amount of from about 3.5 to about 4.5 percent by weight.
Claim 5
Dependent Claim 22 words
A gel as defined in claim 1 wherein said polymer has a molecular weight of from about 4.5 to about 5.5 million.
Claim 6
Dependent Claim 14 words
A gel as defined in claim 1 wherein said buffer is sodium citrate dihydrate.
Claim 7
Dependent Claim 65 words
A gel as defined in claim 1 consisting essentially of about 4 percent by weight of said polymer having a molecular weight of about 5 million, about 0.49 percent by weight sodium chloride, about 0.075 percent by weight potassium chloride, about 0.048 percent by weight calcium chloride, about 0.03 percent by weight magnesium chloride hexahydrate, about 0.17 percent by weight sodium citrate dihydrate, remainder water.

References Cited (Backward Citations)

US3978201A Cited
US3868445A Cited
US3920810A Cited
US4003991A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-09-09 1989-03-11 1989-09-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-09-09 1993-03-11 1993-09-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-09-09 1997-03-11 1997-09-10 $7700.00 Window Closed / Lapsed

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