Base for ophthalmological medicinal preparation on opthalmological medicinal film

Abstract

Abstract A base for ophthalmological medicinal preparations consists of a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and/or a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 per cent acrylamide links. The ophthalmological medicinal film is an oblong plate, 6-9 mm long, 3-5 mm wide and 0.2-0.6 mm thick, of the homopolymer and/or copolymer acrylamide links from 10 to 90 per cent, and an active medicinal ingredient, viz., 3-ethyl-4(1-methyl-5-imidazolyl)-tetrahydrofuran-2-one or atropine, or 3-methoxy-6-sulphanilan idopyridazine, or β-dimethylamino-ethyl-p-butylaminobenzoate, or neamine, or 5-iodo-2-desoxyuridine. The ophthalmological medicinal film is used for treatment of glaucoma of various forms, thrombosis of the central vein of the retina, atrophy of the optic nerve, for dilating the pupil and paralysis of accommodation in treatment of keratitis, iritis, iridocyclitis, ulcers of the cornea, trachoma, herpetic keratitis, uveitis and adenoviral infections, in extraction of foreign objects from the eye, and in various interventions in the organ of vision.

Inventors

• 👤 Gennady Lvovich Khromov
• 👤 Anatoly Borisovich Davydov
• 👤 Jury Fedorovich Maichuk
• 👤 Inna Fedorovna Tishina

Bibliographic Details