US4496446A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Modification of polyglycolic acid structural elements to achieve variable in-vivo physical properties
Assignee: Covidien AG
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Filing: 1983-06-16
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Granted: 1985-01-29
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Expires: 2003-06-16
Abstract
Abstract The physical properties of structural surgical elements which are made from bioabsorbable materials having a glycolic ester linkage can be controlled so that the rate of strength loss and degradation in vivo is altered to achieve disintegration into fragments suitable for removal from or passage through the body without the need for waiting until the material is absorbed. This is achieved by a method of modifying the element through various chemical and/or physical treatments, preferably irradiation, or combinations thereof, with the result that bioabsorbable structural surgical elements are made more controllable in their strength loss and degradation pattern.
Inventors
- 👤 Thomas A. Ritter
- 👤 Alan L. Kaganov
- 👤 John P. Budris
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:26
CPC Classifications
C; C08; C08G; C08G59/00; A; A61; A61L; A61L27/00; A61L27/14; A61L27/18; A61L27/02; A61L27/04; A61L27/40; A61L27/44; A61L27/46; A61L31/00; A61L31/04; A61L31/06; A61L31/12; A61L31/125; C08G65/00; C08K; C08K3/00; C08K3/01; C08K3/013; C08L; C08L67/00; C08L67/04; Y; Y10; Y10S; Y10S522/00; Y10S522/911
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
106 words
A method of modifying a structural surgical element made from a bioabsorbable polymer having a glycolic ester linkage to controllably effect a rapid loss of its in vivo tensile strength, said element selected from the group consisting of a tubular support, tubular implant, tubular stenotic device and ring device, comprising subjecting the element to irradiation treatment in a dosage amount greater than that required for sterilization and in a controllable manner such that the time required for the element to undergo in vivo degradation into fragments, capable of being removed from or passed out of the body without absorption, is from about 8 to 15 days.
Claim 2
Independent Claim
106 words
A method of modifying a structural surgical element made from a bioabsorbable polymer having a glycolic ester linkage to controllably effect a rapid loss of its in vivo tensile strength, said element selected from the group consisting of a tubular support, tubular implant, tubular stenotic device and ring device, comprising subjecting the element to irradiation treatment in a dosage amount greater than that required for sterilization and in a controllable manner such that the time required for the element to undergo in vivo degradation into fragments, capable of being removed from or passed out of the body without absorption, is from about 8 to 15 days.
Claim 3
Dependent Claim
23 words
A method of modifying a structural surgical element as claimed in claim 1 wherein the irradiation dosage is up to about 10 Mrads.
Claim 4
Dependent Claim
61 words
A method of modifying a structural surgical element as claimed in claim 1 or 2 wherein the in vivo degradation into fragments is brought about by a loss of in vivo strength of the element which has been accelerated by the irradiation treatment without significant loss of strength of the element, compared to no irradiation treatment, prior to in vivo implantation.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-01-29 | 1988-07-30 | 1989-01-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-01-29 | 1992-07-30 | 1993-01-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-01-29 | 1996-07-30 | 1997-01-29 | $7700.00 | Window Closed / Lapsed |