US4425347A
Expired / Lapsed
US
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Perfluorobicyclo compound emulsion preparation
Assignee: Tanabe Pharma Corp
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Filing: 1982-12-28
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Granted: 1984-01-10
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Expires: 2002-12-28
Abstract
Abstract A perfluorobicyclo compound emulsion preparation having oxygen carrying ability containing a perfluorobicyclo compound of the general formula: <IMAGE> wherein R represents a perfluoromethyl group or perfluoroethyl group, as an oxygen carrying component.
Inventors
- 👤 Kazumasa Yokoyama
- 👤 Chikara Fukaya
- 👤 Yoshio Tsuda
- 👤 Taizo Ono
- 👤 Yoshio Arakawa
- 👤 Yoshihisa Inoue
- 👤 Youichiro Naito
- 👤 Tadakazu Suyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:42
CPC Classifications
C; C07; C07D; C07D455/00; C07D455/02; A; A01; A01N; A01N1/00; A01N1/10; A01N1/12; A01N1/122; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61P; A61P7/00; A61P7/08
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
60 words
A perfluorobicyclo compound emulsion preparation having oxygen carrying ability comprising 5-50% (w/v) of perfluorobicyclo compound of the general formula ##STR4## wherein R represents a perfluoromethyl group or perfluoroethyl group, as an oxygen carrying component, 1-5% (w/v) of an emulsifying agent and a balance of a physiologically acceptable aqueous solution, and the emulsion having a particle diameter of 0.3μ or less.
Claim 2
Dependent Claim
60 words
A perfluorobicyclo compound emulsion preparation having oxygen carrying ability comprising 5-50% (w/v) of perfluorobicyclo compound of the general formula ##STR4## wherein R represents a perfluoromethyl group or perfluoroethyl group, as an oxygen carrying component, 1-5% (w/v) of an emulsifying agent and a balance of a physiologically acceptable aqueous solution, and the emulsion having a particle diameter of 0.3μ or less.
Claim 3
Dependent Claim
17 words
A preparation according to claim 1, wherein the perfluorobicyclo compound is perfluoro-4-methyloctahydroquinolidine, perfluoro-2-methyloctahydroquinolidine, perfluoro-1-methyloctahydroquinolidine, perfluoro-9a-methyloctahydroquinolidine, or perfluoro-4-ethyloctahydroquinolidine.
Claim 4
Dependent Claim
18 words
A preparation according to claim 1, wherein the emulsifying agent is a polymeric nonionic surfactant or a phospholipid.
Claim 5
Dependent Claim
29 words
A preparation according to claim 1, wherein 0.001-0.01% (w/v) of a fatty acid having 8-22 carbon atoms or a physiologically acceptable salt thereof is added as an emulsifying agent.
Claim 6
Dependent Claim
16 words
A preparation according to claim 1, wherein an isotonizing amount of an isotonizing agent is added.
Claim 7
Dependent Claim
12 words
A preparation according to claim 1, wherein a plasma extender is added.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-01-09 | 1987-07-11 | 1988-01-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-01-09 | 1991-07-11 | 1992-01-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-01-09 | 1995-07-11 | 1996-01-10 | $7700.00 | Window Closed / Lapsed |