Flow metering apparatus for a fluid infusion system

Claim 2

Metering apparatus for use in conjunction with a fluid flow system for infusing fluids at an operator-selected rate into the human body, comprising: metering means including valving means, and a syringe pump having a pump housing and a plunger, said plunger being arranged for reciprocative movement within said housing to provide alternate fill and pump strokes, for establishing in cooperation with said valving means fluid flow through the system; actuator means for operatively engaging and reciprocatively driving said plunger to alternately provide fill strokes of relatively short duration, and pump strokes of relatively longer duration at the operator-selected flow rate, the average flow through the flow system as a result thereof being less than the operator-selected rate as a result of said intervening fill strokes; and flow compensation means for increasing the rate of each of said pump strokes from the operator-selected rate to a relatively higher compensation rate for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at the operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump stroke which compensates for the non-occurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the flow system comprises the operator-selected rate.

Claim 3

Metering apparatus as defined in claim 1 wherein said first and second predetermined compensation periods are substantially equal.

Claim 4

Metering apparatus as defined in claim 1 wherein said syringe pump is contained within a disposable cassette, the actuator means include actuator station, and said cassette is removably received by said actuator station.

Claim 5

Metering apparatus as defined in claim 3 wherein said actuator station includes a reciprocatively driven projecting actuator member, and said plunger is detachably coupled to said member.

Claim 6

Metering apparatus as defined in claim 1 wherein said valving means of the flow system comprises a flow control valve, and said actuator means include valve control means for positioning said valve in a first position during said fill stroke, and in a second position during said pump stroke.

Claim 7

Metering apparatus as defined in claim 1 wherein said compensation rate is approximately four times the uncompensated pump stroke rate.

Claim 8

Metering apparatus as defined in claim 1 wherein said first and second predetermined compensation periods vary as a percentage of the pump stroke according to the operator-selected flow rate.

Claim 9

Metering apparatus as defined in claim 1 wherein said actuator means comprise a stepper motor responsive to applied stepping pulses for driving said syringe, and wherein said actuator means provide stepping pulses to said motor to drive said plunger in said fill and pump strokes.

Claim 10

Metering apparatus as defined in claim 8 wherein said flow compensation means include first register means for counting the stepping pulses applied to said motor during said pump stroke, said compensation periods being initiated following the counting of predetermined numbers of said applied stepping pulses.

Claim 11

Metering apparatus as defined in claim 9 wherein said flow compensation means include second register means for determining the duration of said compensation periods, said second register means being responsive to the counting of a predetermined number of said applied stepping pulses for terminating said compensation periods.

Claim 12

Metering apparatus as defined in claim 10 including computation means responsive to the operator selected rate for establishing said first and second predetermined numbers of stepping pulses required by said first and second register means.

Claim 13

Metering apparatus as defined in claim 11 wherein said computation means comprise a microprocessor.

Claim 16

The method of infusing fluids as defined in claim 13 wherein the first and second compensating portions of each pump stroke are substantially equal.

Claim 17

Metering apparatus for use in conjunction with a fluid flow system for infusing fluids at an operator-selected rate into the human body, comprising: metering means including valving means, and a syringe-type pump in the flow system having a pump housing and a plunger mounted for reciprocative movement within the housing to provide in cooperation with the valve means alternate fill and pump strokes for establishing fluid flow through the system; actuator means including a motor responsive to applied stepping pulses for operatively engaging and reciprocatively driving said plunger; motor drive means for providing stepping pulses to said motor, said stepping pulses occurring at a first relatively high predetermined frequency to advance the plunger at a relatively rapid rate during each fill stroke, and at a second relatively low predetermined frequency to advance the plunger at the operator-selected flow rate during each pump stroke, the average flow through the flow system as a result thereof being less than the operator-selected rate as a result of the intervening fill strokes; and flow compensation means for increasing the frequency of said stepping pulses from said second predetermined frequency to a higher compensating frequency for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at said operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump stroke which compensates for the nonoccurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the infusion system comprises the operator-selected rate.

Claim 18

Metering apparatus for use in conjunction with a fluid flow system for infusing fluids at an operator-selected rate into the human body, comprising: metering means including valving means, and a syringe-type pump in the flow system having a pump housing and a plunger mounted for reciprocative movement within the housing to provide in cooperation with the valve means alternate fill and pump strokes for establishing fluid flow through the system; actuator means including a motor responsive to applied stepping pulses for operatively engaging and reciprocatively driving said plunger; motor drive means for providing stepping pulses to said motor, said stepping pulses occurring at a first relatively high predetermined frequency to advance the plunger at a relatively rapid rate during each fill stroke, and at a second relatively low predetermined frequency to advance the plunger at the operator-selected flow rate during each pump stroke, the average flow through the flow system as a result thereof being less than the operator-selected rate as a result of the intervening fill strokes; and flow compensation means for increasing the frequency of said stepping pulses from said second predetermined frequency to a higher compensating frequency for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at said operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump stroke which compensates for the nonoccurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the infusion system comprises the operator-selected rate.

Claim 19

Metering apparatus as defined in claim 7 wherein said first and second compensation periods are substantially equal.

Claim 20

Metering apparatus as defined in claim 15 wherein said compensation means include first register means for counting the stepping pulses applied to said motor during each pump stroke, said compensation periods being initiated following the counting of a predetermined numbers of said applied stepping pulses.

Claim 21

Metering apparatus as defined in claim 17 wherein said flow compensation means include second register means for determining the duration of said compensation periods, said second register means being responsive to the counting of a predetermined number of said applied stepping pulses for terminating said compensation periods.

Claim 22

Metering apparatus as defined in claim 18 including computation means responsive to the operator designated rate for establishing said first and second predetermined numbers of counted stepping pulses required by said first and second register means.

Claim 23

Metering apparatus for use in conjunction with a disposable single-use fluid flow system of the type having valving means, and a syringe-type cassette pump having a pump housing and a plunger mounted for reciprocative movement within the pump housing to provide alternate fill and pump strokes for establishing in cooperation with the valving means fluid flow through the system for infusing fluids at an operator-selected rate into the human body, comprising: actuator station means for receiving and fixedly positioning the cassette pump; actuator means for operatively engaging and reciprocatively driving the plunger while positioned in said actuator station to provide fill strokes of relatively short duration, and pump strokes of relatively longer duration at the operator-selected flow rate, the average flow through the flow system as a result of the intervening fill strokes being less than the operator-selected rate; and flow compensation means for increasing the rate of each of said pump strokes from the operator-selected rate to a relatively higher compensation rate for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at the operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump strokes which compensates for the non-occurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the flow system comprises the operator-selected rate.

Claim 24

Metering apparatus for use in conjunction with a disposable single-use fluid flow system of the type having valving means, and a syringe-type cassette pump having a pump housing and a plunger mounted for reciprocative movement within the pump housing to provide alternate fill and pump strokes for establishing in cooperation with the valving means fluid flow through the system for infusing fluids at an operator-selected rate into the human body, comprising: actuator station means for receiving and fixedly positioning the cassette pump; actuator means for operatively engaging and reciprocatively driving the plunger while positioned in said actuator station to provide fill strokes of relatively short duration, and pump strokes of relatively longer duration at the operator-selected flow rate, the average flow through the flow system as a result of the intervening fill strokes being less than the operator-selected rate; and flow compensation means for increasing the rate of each of said pump strokes from the operator-selected rate to a relatively higher compensation rate for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at the operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump strokes which compensates for the non-occurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the flow system comprises the operator-selected rate.

Claim 25

Metering apparatus as defined in claim 20 wherein said first and second compensation periods are substantially equal.

Claim 26

Metering apparatus as defined in claim 20 wherein said actuator means include a reciprocatively driven actuator member projecting from said housing, and the plunger is detachably coupled to said actuator member.

Claim 27

Metering apparatus as defined in claim 20 wherein the valving means of the flow system comprise a flow control valve, and said actuator means include valve control means for positioning the valve in a first position during the fill stroke, and in a second position during the pump stroke.

Claim 28

Metering apparatus as defined in claim 20 wherein said actuator means comprise a stepper motor responsive to applied stepping pulses for driving said syringe, and wherein said actuator means provide stepping pulses to said motor to drive said plunger in said fill and pump strokes.

Claim 29

Metering apparatus as defined in claim 24 wherein said flow compensation means include first register means for counting the stepping pulses applied to said motor during said pump stroke, said compensation periods being initiated following the counting of predetermined numbers of said applied stepping pulses.

Claim 30

Metering apparatus as defined in claim 25 wherein said flow compensation means include second register means for determining the duration of said compensation periods, said second register means being responsive to the counting of a predetermined number of said applied stepping pulses for terminating said compensation periods.

Claim 31

Metering apparatus as defined in claim 26 including computation means responsive to the operator selected rate for establishing said first and second predetermined numbers of stepping pulses required by said first and second register means.

Claim 32

Metering apparatus as defined in claim 27 wherein said computation means comprise a microprocessor.

Claim 33

Metering apparatus as defined in claim 20 wherein said compensation rate is approximately four times the uncompensated pump stroke rate.

Claim 34

Metering apparatus for use in conjunction with a disposable single-use fluid flow system of the type including valving means, and a syringe-type cassette pump having a pump housing and a plunger mounted for reciprocative movement within the pump housing to provide alternate fill and pump strokes for establishing in cooperation with the valving means fluid flow through the system for infusing fluids at an operator-selected rate into the human body, comprising: actuator station means for receiving and fixedly positioning the cassette pump; actuator means including a motor responsive to applied stepping pulses for operatively engaging and reciprocatively driving the plunger while positioned in said actuator station; motor drive means for providing stepping pulses to said motor, said stepping pulses occurring at a first relatively high predetermined frequency to advance the plunger at a relatively rapid rate during each fill stroke, and at a second relatively low predetermined frequency to advance the plunger at the operator-selected flow rate during each pump stroke, the average flow through the flow system as a result thereof being less than the operator-selected rate as a result of the intervening fill strokes; and flow compensation means for increasing the frequency of said stepping pulses from said second predetermined frequency to a higher compensating frequency for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at said operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump stroke which compensates for the nonoccurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the infusion system comprises the operator-selected rate.

Claim 35

Metering apparatus for use in conjunction with a disposable single-use fluid flow system of the type including valving means, and a syringe-type cassette pump having a pump housing and a plunger mounted for reciprocative movement within the pump housing to provide alternate fill and pump strokes for establishing in cooperation with the valving means fluid flow through the system for infusing fluids at an operator-selected rate into the human body, comprising: actuator station means for receiving and fixedly positioning the cassette pump; actuator means including a motor responsive to applied stepping pulses for operatively engaging and reciprocatively driving the plunger while positioned in said actuator station; motor drive means for providing stepping pulses to said motor, said stepping pulses occurring at a first relatively high predetermined frequency to advance the plunger at a relatively rapid rate during each fill stroke, and at a second relatively low predetermined frequency to advance the plunger at the operator-selected flow rate during each pump stroke, the average flow through the flow system as a result thereof being less than the operator-selected rate as a result of the intervening fill strokes; and flow compensation means for increasing the frequency of said stepping pulses from said second predetermined frequency to a higher compensating frequency for a first predetermined compensation period immediately following each preceding fill stroke, and for a second predetermined compensation period immediately preceding each succeeding fill stroke, the intervening portion of each pump stroke being at said operator-selected rate, said compensation periods each comprising a substantial portion of a total compensation period during the pump stroke which compensates for the nonoccurrence of pumping action during a fill stroke, whereby the resulting average flow rate through the infusion system comprises the operator-selected rate.

Claim 36

Metering apparatus as defined in claim 30 wherein said first and second compensation periods are substantially equal.

Claim 37

Metering apparatus as defined in claim 31 wherein said compensation means include first register means for counting the stepping pulses applied to said motor during each pump stroke, said compensation periods being initiated following the counting of predetermined numbers of said applied stepping pulses.

Claim 38

Metering apparatus as defined in claim 32 wherein said flow compensation means include second register means for determining the duration of said compensation periods, said second register means being responsive to the counting of a predetermined number of said applied stepping pulses for terminating said compensation periods.

Claim 39

Metering apparatus as defined in claim 33 including computation means responsive to the operator designated rate for establishing said first and second predetermined numbers of counter stepping pulses required by said first and second register means.