Patent US4343798A successfully refreshed from Google Patents.
US4343798A
Expired / Lapsed
US
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Topical antimicrobial anti-inflammatory compositions
Assignee: Procter and Gamble Co
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Filing: 1981-06-23
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Granted: 1982-08-10
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Expires: 2001-06-23
Abstract
Abstract Topical antimicrobial anti-inflammatory compositions, having a pH no greater than about 5, containing C5-C12 fatty acids together with a corticosteroid component, are disclosed. The method of topically treating inflammatory skin conditions using these compositions is also disclosed.
Inventors
- 👤 Mahdi B. Fawzi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:53
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/56; A61K31/57; A61P; A61P29/00; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
44 words
A topical pharmaceutical composition, having a pH no greater than about 5, comprising a safe and effective amount of an antimicrobial agent selected from C 5 -C 12 fatty acids and mixtures thereof, together with a safe and effective amount of a corticosteroid component.
Claim 2
Dependent Claim
44 words
A topical pharmaceutical composition, having a pH no greater than about 5, comprising a safe and effective amount of an antimicrobial agent selected from C 5 -C 12 fatty acids and mixtures thereof, together with a safe and effective amount of a corticosteroid component.
Claim 3
Dependent Claim
66 words
A composition according to claim 1 wherein the corticosteroid component is selected from the group consisting of beclomethasone dipropionate, clobetasol propionate, diflucortolone valerate, fluocinolone acetonide, betamethasone benzoate, betamethasone dipropionate, betamethasone valerate, desonide, desoxymethasone, diflorasone diacetate, fluclorolone acetonide, fluocinonide, fluocortolone, fluprednidene (fluprednylidene) acetate, flurandrenolone, halcinonide, hydrocortisone butyrate, triamcinolone acetonide, clobetasone butyrate, flumethasone pivalate, fluocortin butylester, hydrocortisone with urea, dexamethasone, hydrocortisone alcohol or acetate, methylprednisolone, and mixtures thereof.
Claim 4
Dependent Claim
17 words
A composition according claim 2 which contains from about 0.5% to about 20% of the antimicrobial agent.
Claim 5
Dependent Claim
18 words
A composition according to claim 3 which contains from about 0.01% to about 10% of the corticosteroid component.
Claim 6
Dependent Claim
20 words
A composition according to claim 4 which additionally contains from about 1% to about 99.5% of a pharmaceutically-acceptable topical carrier.
Claim 7
Dependent Claim
22 words
A composition according to claim 5 wherein the antimicrobial agent is selected from C 6 -C 10 fatty acids and mixtures thereof.
Claim 8
Dependent Claim
20 words
A composition according to claim 6 wherein the antimicrobial agent is selected from octanoic acid, decanoic acid, and mixtures thereof.
Claim 9
Dependent Claim
27 words
A composition according to claim 7 wherein the corticosteroid component is selected from the group consisting of triamcinolone acetonide, hydrocortisoneacetate, betamethasone valerate, fluocinolone acetonide, and mixtures thereof.
Claim 10
Dependent Claim
18 words
A composition according to claim 8 which contains from about 1% to about 10% of the antimicrobial agent.
Claim 11
Dependent Claim
18 words
A composition according to claim 9 which contains from about 0.02% to about 5% of the corticosteroid component.
Claim 12
Dependent Claim
13 words
A composition according to claim 10 wherein the corticosteroid component is triamcinolone acetonide.
Claim 13
Dependent Claim
13 words
A composition according to claim 2 wherein the corticosteroid component is triamcinolone acetonide.
Claim 14
Dependent Claim
13 words
A composition according to claim 2 wherein the antimicrobial agent is octanoic acid.
Claim 15
Dependent Claim
14 words
A composition according to claim 2 having a pH no greater than about 4.
Claim 16
Dependent Claim
17 words
A composition according to claim 2 in the form of an aqueous gel or an aqueous lotion.
Claim 17
Dependent Claim
32 words
A method of treating inflammatory skin conditions in humans or animals comprising the topical application to the afflicted situs of a safe and effective amount of the composition according to claim 2.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-08-09 | 1986-02-08 | 1986-08-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-08-09 | 1990-02-08 | 1990-08-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-08-09 | 1994-02-08 | 1994-08-10 | $7700.00 | Window Closed / Lapsed |