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US4302441A Expired / Lapsed US ⏱️ 0.0 years remaining

Solid oral preparations of urea hydrogen peroxide without glycerol

Assignee: Individual
•
Filing: 1980-04-11
•
Granted: 1981-11-24
•
Expires: 2000-04-11
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Abstract

Abstract Solid oral preparations comprising active urea hydrogen peroxide without glycerol are effective in countering acid formed from fermentable carbohydrates in dental plaques.

Inventors

  • 👤 Hans R. Muhlemann
  • 👤 Allen R. Firestone
  • 👤 Thomas Imfeld

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:49
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/02; A61K8/0216; A61K8/18; A61K8/19; A61K8/22; A61K8/30; A61K8/40; A61K8/42

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 79 words
A solid orally administrable composition in the form of lozenge, tablet or chewing gum for neutralizing acid in dental plaque which composition comprises as active ingredient urea hydrogen peroxide in an amount effective to neutralize said acid and up to 15% by weight and in the absence of glycerol together with a sweetner selected from the group consisting of mannitol, sorbitol xylitol and saccharin and a carrier selected from the group consisting of soluble cellulose ethers and carbohydrate gums.
Claim 2
Dependent Claim 79 words
A solid orally administrable composition in the form of lozenge, tablet or chewing gum for neutralizing acid in dental plaque which composition comprises as active ingredient urea hydrogen peroxide in an amount effective to neutralize said acid and up to 15% by weight and in the absence of glycerol together with a sweetner selected from the group consisting of mannitol, sorbitol xylitol and saccharin and a carrier selected from the group consisting of soluble cellulose ethers and carbohydrate gums.
Claim 3
Dependent Claim 16 words
A composition according to claim 1 which contains 9 to 11% by weight urea hydrogen peroxide.
Claim 4
Dependent Claim 12 words
A composition according to claim 1 in the form of chewing gum.
Claim 5
Dependent Claim 12 words
A composition according to claim 1 in the form of a tablet.
Claim 6
Dependent Claim 15 words
A composition according to claim 4 containing 9 to 15% by weight urea hydrogen peroxide.
Claim 7
Dependent Claim 12 words
A composition according to claim 1 wherein the sweetener is sodium saccharinate.
Claim 8
Dependent Claim 24 words
A composition according to claim 6 including at least one member from the group consisting of methyl cellulose, ethyl cellulose and sodium carboxymethyl cellulose.
Claim 9
Dependent Claim 10 words
A composition according to claim 6 including a carbohydrate gum.
Claim 10
Dependent Claim 35 words
A composition according to claim 1 in tablet form consisting essentially of ______________________________________ methyl cellulose about 62% sodium carboxymethyl cellulose about 26-27% sodium saccharinate about 0.9% flavor about 0.9% urea hydrogen peroxide about 10% ______________________________________
Claim 11
Dependent Claim 34 words
A composition according to claim 1 in tablet form consisting essentially of ______________________________________ gum arabic about 55-56% ethyl cellulose about 32-33% sodium saccharinate about 0.9% flavor about 0.9% urea hydrogen peroxide about 10% ______________________________________
Claim 12
Dependent Claim 35 words
A composition according to claim 1 in tablet form consisting essentially of ______________________________________ methyl cellulose about 62% sodium carboxymethyl cellulose about 26-27% sodium saccharinate about 0.9% flavor about 0.9% urea hydrogen peroxide about 10% ______________________________________
Claim 13
Dependent Claim 16 words
A method for neutralizing acid in dental plaque comprising orally taking the composition of claim 1.
Claim 14
Dependent Claim 16 words
A method according to claim 12 wherein the composition contains 9 to 11% urea hydrogen peroxide.
Claim 15
Dependent Claim 21 words
A composition according to claim 1 in the form of a 0.2 gram tablet containing 0.02 gram of urea hydrogen peroxide.
Claim 16
Dependent Claim 14 words
A composition according to claim 1 containing up to 10% of urea hydrogen peroxide.
Claim 17
Dependent Claim 57 words
A method for neutralizing acid in dental plaque comprising orally taking the composition of claim 1 in an amount effective to release urea into the saliva and to diffuse freely on the oral mucosa and penetrate into agglomerates of microorganisms on the teeth and react with the enzyme urease to form ammonia and thereby neutralize the acid.

References Cited (Backward Citations)

DE1617430C3 Cited
DE2341176A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-11-23 1985-05-25 1985-11-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-11-23 1989-05-25 1989-11-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-11-23 1993-05-25 1993-11-24 $7700.00 Window Closed / Lapsed

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