US4302441A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Solid oral preparations of urea hydrogen peroxide without glycerol
Assignee: Individual
•
Filing: 1980-04-11
•
Granted: 1981-11-24
•
Expires: 2000-04-11
Abstract
Abstract Solid oral preparations comprising active urea hydrogen peroxide without glycerol are effective in countering acid formed from fermentable carbohydrates in dental plaques.
Inventors
- 👤 Hans R. Muhlemann
- 👤 Allen R. Firestone
- 👤 Thomas Imfeld
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:28
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/02; A61K8/0216; A61K8/18; A61K8/19; A61K8/22; A61K8/30; A61K8/40; A61K8/42
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
79 words
A solid orally administrable composition in the form of lozenge, tablet or chewing gum for neutralizing acid in dental plaque which composition comprises as active ingredient urea hydrogen peroxide in an amount effective to neutralize said acid and up to 15% by weight and in the absence of glycerol together with a sweetner selected from the group consisting of mannitol, sorbitol xylitol and saccharin and a carrier selected from the group consisting of soluble cellulose ethers and carbohydrate gums.
Claim 2
Dependent Claim
79 words
A solid orally administrable composition in the form of lozenge, tablet or chewing gum for neutralizing acid in dental plaque which composition comprises as active ingredient urea hydrogen peroxide in an amount effective to neutralize said acid and up to 15% by weight and in the absence of glycerol together with a sweetner selected from the group consisting of mannitol, sorbitol xylitol and saccharin and a carrier selected from the group consisting of soluble cellulose ethers and carbohydrate gums.
Claim 3
Dependent Claim
16 words
A composition according to claim 1 which contains 9 to 11% by weight urea hydrogen peroxide.
Claim 4
Dependent Claim
12 words
A composition according to claim 1 in the form of chewing gum.
Claim 5
Dependent Claim
12 words
A composition according to claim 1 in the form of a tablet.
Claim 6
Dependent Claim
15 words
A composition according to claim 4 containing 9 to 15% by weight urea hydrogen peroxide.
Claim 7
Dependent Claim
12 words
A composition according to claim 1 wherein the sweetener is sodium saccharinate.
Claim 8
Dependent Claim
24 words
A composition according to claim 6 including at least one member from the group consisting of methyl cellulose, ethyl cellulose and sodium carboxymethyl cellulose.
Claim 9
Dependent Claim
10 words
A composition according to claim 6 including a carbohydrate gum.
Claim 10
Dependent Claim
35 words
A composition according to claim 1 in tablet form consisting essentially of ______________________________________
methyl cellulose about 62%
sodium carboxymethyl cellulose
about 26-27%
sodium saccharinate about 0.9%
flavor about 0.9%
urea hydrogen peroxide about 10%
______________________________________
Claim 11
Dependent Claim
34 words
A composition according to claim 1 in tablet form consisting essentially of ______________________________________
gum arabic about 55-56%
ethyl cellulose about 32-33%
sodium saccharinate about 0.9%
flavor about 0.9%
urea hydrogen peroxide about 10%
______________________________________
Claim 12
Dependent Claim
35 words
A composition according to claim 1 in tablet form consisting essentially of ______________________________________
methyl cellulose about 62%
sodium carboxymethyl cellulose
about 26-27%
sodium saccharinate about 0.9%
flavor about 0.9%
urea hydrogen peroxide about 10%
______________________________________
Claim 13
Dependent Claim
16 words
A method for neutralizing acid in dental plaque comprising orally taking the composition of claim 1.
Claim 14
Dependent Claim
16 words
A method according to claim 12 wherein the composition contains 9 to 11% urea hydrogen peroxide.
Claim 15
Dependent Claim
21 words
A composition according to claim 1 in the form of a 0.2 gram tablet containing 0.02 gram of urea hydrogen peroxide.
Claim 16
Dependent Claim
14 words
A composition according to claim 1 containing up to 10% of urea hydrogen peroxide.
Claim 17
Dependent Claim
57 words
A method for neutralizing acid in dental plaque comprising orally taking the composition of claim 1 in an amount effective to release urea into the saliva and to diffuse freely on the oral mucosa and penetrate into agglomerates of microorganisms on the teeth and react with the enzyme urease to form ammonia and thereby neutralize the acid.
References Cited (Backward Citations)
DE1617430C3
Cited
DE2341176A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-23 | 1985-05-25 | 1985-11-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-23 | 1989-05-25 | 1989-11-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-23 | 1993-05-25 | 1993-11-24 | $7700.00 | Window Closed / Lapsed |