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Apparatus for the detoxification of blood

Assignee: Dr Eduard Fresenius Chemisch Pharmazeutische Industrie KG Apparatebau KG
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Filing: 1979-09-07
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Granted: 1981-04-14
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Expires: 1999-09-07
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Abstract

Abstract A blood detoxification apparatus comprises a housing filled with a plurality of substantially spherical reaction bodies. Each reaction body comprises an embedding material and active ingredient particles such as adsorbents and/or enzymes embedded in the embedding material which is blood compatible but nonpermeable for corpuscular blood components. The active ingredients may have a dust or powder or granular consistency but are substantially smaller in diameter than the reaction bodies which may be distributed in layers in said housing whereby the active ingredients in different layers may be different.

Inventors

  • 👤 Gorig Brunner
  • 👤 Christopher-John Holloway
  • 👤 Wilfried Schal

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 15:58
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/36; A61M1/3679

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 115 words
An apparatus for the detoxification of blood, comprising container means (1) having an inlet opening and an outlet opening, a plurality of reaction bodies (5) operatively held in said container means each of said reaction bodies having a given size, each of said reaction bodies comprising a blood compatible embedding material which is nonpermeable for corpuscular blood components and permeable to substances in solution to provide a molecular sieve, each of said reaction bodies having embedded therein active means in the form of a plurality of particles relatively smaller in size than said given size, said embedding material holding together said active particles in a substantially uniform distribution of the particle in the embedding material.
Claim 2
Independent Claim 115 words
An apparatus for the detoxification of blood, comprising container means (1) having an inlet opening and an outlet opening, a plurality of reaction bodies (5) operatively held in said container means each of said reaction bodies having a given size, each of said reaction bodies comprising a blood compatible embedding material which is nonpermeable for corpuscular blood components and permeable to substances in solution to provide a molecular sieve, each of said reaction bodies having embedded therein active means in the form of a plurality of particles relatively smaller in size than said given size, said embedding material holding together said active particles in a substantially uniform distribution of the particle in the embedding material.
Claim 3
Dependent Claim 12 words
The apparatus of claim 1, wherein said active means comprise adsorption means.
Claim 4
Dependent Claim 12 words
The apparatus of claim 1, wherein said active means comprise enzyme means.
Claim 5
Dependent Claim 27 words
The apparatus of claim 1, wherein said reaction bodies further comprise outer surface layer means also made of said blood compatible, embedding material forming a molecular sieve.
Claim 6
Dependent Claim 43 words
The apparatus of claim 1, wherein said reaction bodies further comprise outer surface layer means made of a blood compatible material other than said first mentioned embedding material, said other material also being nonpermeable for corpuscular blood components but forming a molecular sieve.
Claim 7
Dependent Claim 23 words
The apparatus of claim 1, wherein said particles of said active means comprise carrier means and organic substances bound by said carrier means.
Claim 8
Dependent Claim 25 words
The apparatus of claim 1, wherein said active means comprise a mixture of different active components held in said embedding material of said reaction bodies.
Claim 9
Dependent Claim 15 words
The apparatus of claim 1, wherein said reaction bodies comprise different types of reaction bodies.
Claim 10
Dependent Claim 22 words
The apparatus of claim 8, wherein said different types of reaction bodies are arranged in a layer sequence in said housing means.
Claim 11
Dependent Claim 14 words
The apparatus of claim 1, wherein said reaction bodies have a substantially spherical shape.
Claim 12
Dependent Claim 12 words
The apparatus of claim 10, wherein said reaction bodies have different diameters.
Claim 13
Dependent Claim 11 words
The apparatus of claim 1, wherein said embedding material comprises agarose.

References Cited (Backward Citations)

US2682268A Cited
US3442819A Cited
US3420709A Cited
US3808124A Cited
US4190542A Cited
US4048018A Cited
US4131544A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-04-13 1984-10-13 1985-04-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-04-13 1988-10-13 1989-04-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-04-13 1992-10-13 1993-04-14 $7700.00 Window Closed / Lapsed

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