Patent US4259323A successfully refreshed from Google Patents.
US4259323A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Potassium chloride emulsion
Assignee: Hoffmann La Roche Inc
•
Filing: 1980-03-24
•
Granted: 1981-03-31
•
Expires: 2000-03-24
Abstract
Abstract An improved potassium chloride emulsion having an acceptable taste is disclosed. The disclosed emulsion is a water-in-oil emulsion comprising, per liter, 500 to 700 ml. water, 8 percent to 24 percent weight to volume sorbitol, 100 to 300 ml. of an edible, non-polar oil, 5 percent to 15 percent by weight potassium chloride, 1 percent to 5 percent weight to volume purified bentonite, 10 to 30 ml. of one or a mixture of edible liquid, non-polar esters of unsaturated fatty acids, 0.01 percent to 1.0 percent weight to volume polysorbate 80, and 0 percent to 3 percent by weight lecithin and 0 percent to 5 percent by weight ascorbyl palmitate with suitable, pharmaceutically acceptable preservatives, flavors and sweetening agents.
Inventors
- 👤 Joseph A. Ranucci
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:11
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0095; A61K33/00; A61K33/06; A61K33/14
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
141 words
An improved potassium chloride water-in-oil emulsion comprising, per liter: (a) from about 500 ml. to about 700 ml. water; (b) from about 8 percent to about 24 percent weight to volume sorbitol; (c) from about 100 ml. to about 300 ml. of mineral oil, U.S.P.; (d) from about 5 percent to about 15 percent by weight potassium chloride; (e) from about 1 percent to about 5 percent weight to volume purified bentonite; (f) from about 10 ml. to about 30 ml. of a mixture of monoglycerides and diglycerides of 16 to 18 carbon atom unsalurated fatty acids; (g) from about 0.01 percent to about 1.0 percent weight to volume polysorbate 80; (h) from 0 to about 3 percent by weight lecithin; (i) from 0 to about 5 percent by weight ascorbyl palmitate; and (j) pharmaceutically acceptable preservatives, flavors and sweetening agents.
Claim 2
Dependent Claim
141 words
An improved potassium chloride water-in-oil emulsion comprising, per liter: (a) from about 500 ml. to about 700 ml. water; (b) from about 8 percent to about 24 percent weight to volume sorbitol; (c) from about 100 ml. to about 300 ml. of mineral oil, U.S.P.; (d) from about 5 percent to about 15 percent by weight potassium chloride; (e) from about 1 percent to about 5 percent weight to volume purified bentonite; (f) from about 10 ml. to about 30 ml. of a mixture of monoglycerides and diglycerides of 16 to 18 carbon atom unsalurated fatty acids; (g) from about 0.01 percent to about 1.0 percent weight to volume polysorbate 80; (h) from 0 to about 3 percent by weight lecithin; (i) from 0 to about 5 percent by weight ascorbyl palmitate; and (j) pharmaceutically acceptable preservatives, flavors and sweetening agents.
Claim 3
Dependent Claim
37 words
An emulsion in accordance with claim 1 wherein said ingredient (b) is Sorbitol Solution, U.S.P., and the ratio of said ingredient (f) to said ingredient (b) on a volume-to-volume basis is from about 1:5 to about 1:20.
Claim 4
Dependent Claim
20 words
An emulsion in accordance with claim 2 wherein the ratio of said ingredient (f) to said ingredient (b) is 1:9.
Claim 5
Dependent Claim
110 words
An emulsion in accordance with claim 1 wherein said emulsion comprises, per liter; (a) about 600 ml. water; (b) about 16 percent weight to volume sorbitol; (c) about 200 ml. of mineral oil, U.S.P.; (d) about 10 percent by weight potassium chloride; (e) about 1 percent weight to volume purified bentonite; (f) about 20 ml. of a mixture of monoglycerides and diglycerides of 16 to 18 carbon atom unsaturated fatty acids; (g) about 0.3 percent weight to volume polysorbate 80; (h) from 0 to about 3 percent by weight lecithin; (i) from 0 to about 5 percent by weight ascorbyl palmitate; and (j) pharmaceutically acceptable preservatives, flavors and sweetening agents.
Claim 6
Dependent Claim
29 words
An emulsion in accordance with claim 1 wherein said pharmaceutically acceptable preservatives, flavors and sweetening agents comprises from about 0.01 to about 1.0 percent by weight of said emulsion.
Claim 7
Dependent Claim
19 words
An emulsion in accordance with claims 1 or 4 wherein said emulsion contains about 0.5 percent by weight lecithin.
Claim 8
Dependent Claim
20 words
An emulsion in accordance with claims 1 or 4, wherein said emulsion contains about 0.5 percent by weight ascorbyl palmitate.
References Cited (Backward Citations)
US3903255A
Cited
US3821368A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-30 | 1984-09-29 | 1985-03-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-30 | 1988-09-29 | 1989-03-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-30 | 1992-09-29 | 1993-03-31 | $7700.00 | Window Closed / Lapsed |