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New tunicamine derivatives and their preparation

Assignee: Meiji Seika Kaisha Ltd
•
Filing: 1978-06-29
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Granted: 1980-05-13
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Expires: 1998-06-29
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Abstract

Abstract New tunicamine derivatives are provided which exhibit antiviral activity against some virus, particularly Newcastle disease virus, and inhibitory activity against coccidiosis and which are also of particular value as intermediates for the preparation of a variety of useful antibacterial, antitumor and antiviral compounds. They have a structure of the formula: <IMAGE> (I) wherein R represents hydrogen or a fatty acid residue of the formula (CH3)2CH(CH2)nCH=CHCO- where n represents an integer of 8 to 11 inclusive. They are prepared either by fermentation methods or by acid hydrolysis of the known antibiotic tunicamycin.

Inventors

  • 👤 Gakuzo Tamura
  • 👤 Akira Takatsuki

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 11:01
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; A; A61; A61P; A61P31/00; A61P31/12; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P19/00; C12P19/26; C12P19/28; C12P19/38; C12P19/385; C12R; C12R2001/00; C12R2001/01; C12R2001/465

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 37 words
A tunicamine derivative of the formula: ##STR6## wherein R represents hydrogen or a fatty acid residue of the formula (CH 3 ) 2 CH(CH 2 ) n CH═CHCO--where n represents an integer of 8 to 11 inclusive.
Claim 2
Dependent Claim 37 words
A tunicamine derivative of the formula: ##STR6## wherein R represents hydrogen or a fatty acid residue of the formula (CH 3 ) 2 CH(CH 2 ) n CH═CHCO--where n represents an integer of 8 to 11 inclusive.
Claim 3
Dependent Claim 21 words
A tunicamine derivative according to claim 1 which is designated as tunicamine derivative C and which is of the formula: ##STR7##
Claim 4
Dependent Claim 36 words
A tunicamine derivative according to claim 1 which is in the form of a mixture designated as tunicamine derivative B and which is of the formula: ##STR8## wherein n represents integers of 8 to 11 inclusive.

References Cited (Backward Citations)

JPS4829156A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-05-13 1983-11-12 1984-05-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-05-13 1987-11-12 1988-05-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-05-13 1991-11-12 1992-05-13 $7700.00 Window Closed / Lapsed

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